thiophenes has been researched along with Anemia, Sickle Cell in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Berto-Junior, C; Guimarães-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Teixeira-Alves, LR | 1 |
| Ataga, KI; Frelinger, AL; Heath, LE; Jakubowski, JA; Knupp, CL; Krishnamurti, L; Kutlar, A; McMahon, LE; Novelli, EM; Nwachuku, CE; Riesmeyer, JS; Soulieres, D; Strouse, JJ; Winters, KJ; Wun, T; Zhou, C | 1 |
| Frelinger, AL; Gupta, N; Howard, J; Jakubowski, JA; Jurcevic, S; Lachno, DR; Mant, TG; Payne, CD; Winters, KJ; Zhou, C | 1 |
| Chantrathammachart, P; Hebbel, RP; Key, NS; Mackman, N; Mickelson, J; Monroe, DM; Pawlinski, R; Sparkenbaugh, EM; van Ryn, J | 1 |
| Jakubowski, JA; Mizuno, M; Ohno, K; Samata, N; Sugidachi, A; Tanaka, H; Tomizawa, A | 1 |
| Heath, LE; Heeney, MM; Heiselman, D; Jakubowski, JA; Kanter, J; Moser, BA; Quinn, CT; Rana, SR; Redding-Lallinger, R; Small, DS; Styles, L; Winters, KJ; Zhou, C | 1 |
| Campbell, A; Cui, S; DeSimone, J; Engel, JD; Harro, D; Iwase, S; Jearawiriyapaisarn, N; Lavelle, D; Lee, M; Lim, KC; Myers, G; Rivers, A; Saunthararajah, Y; Shi, L; Trievel, RC | 1 |
| Cui, S; DeSimone, J; Engel, JD; Ibanez, V; Lavelle, D; Molokie, R; Rivers, A; Vaitkus, K | 1 |
| Cui, S; DeSimone, J; Diamond, AM; Engel, JD; Ganesh, BB; Ibanez, V; Jagadeeswaran, R; Lavelle, D; Molokie, RE; Rivers, A; Thiruppathi, M; Vazquez, BA | 1 |
| Frelinger, AL; Howard, J; Jakubowski, JA; Jurcevic, S; Lachno, DR; Mant, TG; Payne, CD; Small, DS; Winters, KJ; Zhou, C | 1 |
| Cabannes, R; Castaigne, JP; Lonsdorfer, J; Ondo, A; Plassard, A; Zohoun, I | 1 |
| Day, HJ | 1 |
| Al-Hasani, SF; Kioy, P; Savidge, GF; Semple, MJ | 1 |
| Bogui, P; Cabannes, R; Castaigne, JP; Dosso, Y; Lenormand, E; Lonsdorfer, J; Otayeck, A | 1 |
| Berkowitz, LR; Orringer, EP | 1 |
| Benjamin, LJ; Kokkini, G; Peterson, CM | 1 |
| Castaigne, JP; Labie, D; Sablayrolles, M; Wajcman, H | 1 |
1 review(s) available for thiophenes and Anemia, Sickle Cell
| Article | Year |
|---|---|
Overview: clinical experiences with ticlopidine.
Topics: Anemia, Sickle Cell; Anticoagulants; Arterial Occlusive Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Artery Bypass; Extracorporeal Circulation; Humans; Renal Dialysis; Retinal Diseases; Subarachnoid Hemorrhage; Thiophenes; Ticlopidine | 1984 |
7 trial(s) available for thiophenes and Anemia, Sickle Cell
| Article | Year |
|---|---|
A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Biomarkers, Tumor; Cell Adhesion Molecules; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Microfilament Proteins; Middle Aged; Pain; Phosphoproteins; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Prognosis; Purinergic P2Y Receptor Antagonists; Thiophenes; Young Adult | 2013 |
A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation.
Topics: Adenosine Diphosphate; Adult; Anemia, Sickle Cell; Biomarkers; Blood Coagulation; Blood Platelets; Female; Humans; Male; Middle Aged; Piperazines; Platelet Activation; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes; Young Adult | 2014 |
Prasugrel in children with sickle cell disease: pharmacokinetic and pharmacodynamic data from an open-label, adaptive-design, dose-ranging study.
Topics: Adolescent; Anemia, Sickle Cell; Child; Child, Preschool; Female; Humans; Male; Models, Biological; Piperazines; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Research Design; Thiophenes | 2015 |
A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity.
Topics: Adult; Anemia, Sickle Cell; Blood Platelets; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Humans; Male; Piperazines; Platelet Function Tests; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Thiophenes; Young Adult | 2013 |
Clinical and biological double-blind-study of ticlopidine in preventive treatment of sickle-cell disease crises.
Topics: Anemia, Sickle Cell; Anticoagulants; Clinical Trials as Topic; Double-Blind Method; Humans; Thiophenes; Ticlopidine | 1984 |
Overview: clinical experiences with ticlopidine.
Topics: Anemia, Sickle Cell; Anticoagulants; Arterial Occlusive Diseases; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Artery Bypass; Extracorporeal Circulation; Humans; Renal Dialysis; Retinal Diseases; Subarachnoid Hemorrhage; Thiophenes; Ticlopidine | 1984 |
A double-blind trial of ticlopidine in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Anticoagulants; Blood Coagulation Factors; Blood Platelets; Cell Survival; Clinical Trials as Topic; Double-Blind Method; Female; Heterozygote; Homozygote; Humans; Male; Placebos; Thalassemia; Thiophenes; Ticlopidine | 1984 |
10 other study(ies) available for thiophenes and Anemia, Sickle Cell
| Article | Year |
|---|---|
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes.
Topics: Acrylates; Anemia, Sickle Cell; Angiotensin II; Annexin A5; Erythrocytes; Hemoglobin, Sickle; Humans; Imidazoles; Losartan; Phosphatidylserines; Polymerization; Receptor, Angiotensin, Type 1; Thiophenes | 2022 |
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Anticoagulants; Antithrombins; Benzimidazoles; beta-Alanine; Bone Marrow Transplantation; Dabigatran; Disease Models, Animal; Factor Xa; Factor Xa Inhibitors; Female; Immunoenzyme Techniques; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Receptor, PAR-1; Receptor, PAR-2; Rivaroxaban; Thiophenes; Thrombin; Vascular Diseases | 2014 |
Platelet activation biomarkers in Berkeley sickle cell mice and the response to prasugrel.
Topics: Anemia, Sickle Cell; Animals; Biomarkers; Blood Platelets; Female; Male; Mice; P-Selectin; Piperazines; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prasugrel Hydrochloride; Purinergic P2Y Receptor Antagonists; Thiophenes | 2014 |
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice.
Topics: Anemia, Sickle Cell; Animals; beta-Globins; Blotting, Western; Cells, Cultured; Disease Models, Animal; Fetal Hemoglobin; Flow Cytometry; Histone Demethylases; Humans; Immunoenzyme Techniques; Mice; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rhodamines; RNA, Messenger; Spiro Compounds; Splenomegaly; Thiophenes | 2015 |
Efficacy and safety of long-term RN-1 treatment to increase HbF in baboons.
Topics: Anemia, Sickle Cell; Animals; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fetal Hemoglobin; Histone Demethylases; Papio; Rhodamines; Spiro Compounds; Thiophenes | 2017 |
Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease.
Topics: Anemia, Sickle Cell; Animals; Disease Models, Animal; Erythrocytes; Histone Demethylases; Humans; Mice; Mitochondria; Models, Biological; Reactive Oxygen Species; Rhodamines; Sirolimus; Spiro Compounds; Thiophenes; TOR Serine-Threonine Kinases | 2017 |
Beneficial effects of ticlopidine on cardiopulmonary function of sickle cell patients not in crisis.
Topics: Adult; Anemia, Sickle Cell; Anticoagulants; Heart; Heart Rate; Humans; Lung; Oxygen; Physical Exertion; Thiophenes; Ticlopidine | 1984 |
Effect of cetiedil, an in vitro antisickling agent, on erythrocyte membrane cation permeability.
Topics: Anemia, Sickle Cell; Antisickling Agents; Azepines; Biological Transport, Active; Calcium; Cell Membrane Permeability; Dose-Response Relationship, Drug; Erythrocyte Membrane; Erythrocytes; Humans; Ouabain; Potassium; Sodium; Thiophenes | 1981 |
Cetiedil: its potential usefulness in sickle cell disease.
Topics: Analgesics; Anemia, Sickle Cell; Animals; Azepines; Binding Sites; Cell Survival; Cyanates; Dogs; Drug Combinations; Erythrocyte Membrane; Erythrocytes, Abnormal; Filtration; Globins; Hemoglobins; Humans; Thiophenes; Vasodilator Agents | 1980 |
Membrane expansion as a mechanism explaining the antisickling action of ticlopidine observed in vitro.
Topics: Anemia, Sickle Cell; Antisickling Agents; Densitometry; Erythrocyte Membrane; Humans; Kinetics; Osmotic Fragility; Oxygen Consumption; Sickle Cell Trait; Thiophenes; Ticlopidine | 1985 |