thiophenes has been researched along with Anaphylactic Reaction in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baggiolini, M; Martin, U | 1 |
| Díaz, R; Portolés, A; Rojo, JM | 1 |
| Kumagai, A; Muranaka, M; Shida, T; Takahashi, T; Tomioka, H | 1 |
| Lane, DJ | 1 |
| Leistner, S; Vieweg, H; Wagner, G | 1 |
| Alise, G; Apolito, A; Lampa, E; Pedone, P; Russo, G | 1 |
| Martin, U; Römer, D | 1 |
| Hurme, R; Mattson, K; Poppius, H | 1 |
| Martin, U; Roemer, D | 1 |
| Briel, D | 1 |
| Bertsch, B; Esterman, M; Ho, PP; Panetta, JA | 1 |
| Ojeda, G; Portolés, A; Portolés, MP; Rojo, JM | 1 |
| Davies, GE | 1 |
2 trial(s) available for thiophenes and Anaphylactic Reaction
| Article | Year |
|---|---|
Clinical evaluation of a new orally active anti-anaphylactic compound: ketotifen (HC 20-511) in Japanese adult asthmatics.
Topics: Adult; Anaphylaxis; Asthma; Basophils; Cromolyn Sodium; Double-Blind Method; Humans; Hypersensitivity, Immediate; Japan; Ketotifen; Mast Cells; Piperidines; Placebos; Thiophenes | 1980 |
A controlled study on the preventive effect of ketotifen, an antiallergic agent, on methacholine-induced bronchoconstriction in asthmatics.
Topics: Adolescent; Adult; Anaphylaxis; Asthma; Bronchial Spasm; Dose-Response Relationship, Drug; Double-Blind Method; Histamine H1 Antagonists; Humans; Methacholine Compounds; Middle Aged; Piperidines; Spirometry; Thiophenes | 1979 |
11 other study(ies) available for thiophenes and Anaphylactic Reaction
| Article | Year |
|---|---|
Dissociation between the anti-anaphylactic and the anti-histaminic actions of ketotifen.
Topics: Airway Resistance; Anaphylaxis; Animals; Antigens; Clemastine; Female; Histamine H1 Antagonists; Ketotifen; Piperidines; Pyrilamine; Rats; Skin Tests; Thiophenes | 1981 |
[Quantification (by nomograms) of physiopathological parameters in an experimental model of passive anaphylaxis caused by immune complexes].
Topics: Anaphylaxis; Animals; Cyproheptadine; Immune Complex Diseases; Mathematics; Mice; Mice, Inbred Strains; Shock, Septic; Thiophenes; Ticlopidine | 1984 |
A steroid sparing effect of ketotifen in steroid-dependent asthmatics.
Topics: Adult; Aged; Anaphylaxis; Asthma; Cromolyn Sodium; Double-Blind Method; Female; Humans; Ketotifen; Male; Middle Aged; Peak Expiratory Flow Rate; Piperidines; Placebos; Prednisolone; Substance-Related Disorders; Thiophenes | 1980 |
[Synthesis of 4-methyl-6-phenyl-thieno(2,3-d)pyrimidines with a formamidino- or oxalamidocarbonic acid residue with antianaphylactic activity].
Topics: Anaphylaxis; Animals; Passive Cutaneous Anaphylaxis; Pyridines; Rats; Thiophenes | 1993 |
[Specific and aspecific activity of an antihistaminic of the H1 type: HC 20-511 or ketothiphen (benzo-cyclohepta-thiophenone derivative)].
Topics: Albuterol; Anaphylaxis; Animals; Anura; Bronchial Spasm; Cardiovascular System; Chlorpheniramine; Dogs; Drug Evaluation, Preclinical; Female; Gastric Juice; Guinea Pigs; Histamine H1 Antagonists; Inflammation; Male; Mice; Muscle, Smooth; Piperidines; Pizotyline; Rats; Respiration; Stomach Ulcer; Thiophenes | 1977 |
The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene.
Topics: Anaphylaxis; Anesthetics, Local; Animals; Cats; Central Nervous System Agents; Dogs; Female; Guinea Pigs; Haplorhini; Hemodynamics; Histamine Antagonists; Histamine H1 Antagonists; In Vitro Techniques; Kidney; Macaca mulatta; Male; Mice; Parasympatholytics; Phosphodiesterase Inhibitors; Piperidines; Rats; Serotonin Antagonists; Thiophenes | 1978 |
Ketotifen: a histamine release inhibitor.
Topics: Anaphylaxis; Animals; Clemastine; Cromolyn Sodium; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Histamine Release; Ovalbumin; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Piperidines; Rats; Thiophenes | 1977 |
[New heterocyclic systems for thiophene-2-thiolates--synthesis and biological activity].
Topics: Anaphylaxis; Animals; Anti-Ulcer Agents; Anticonvulsants; Cell Survival; Heterocyclic Compounds; Hypersensitivity; Oxazepines; Oxazines; Pyrimidines; Rats; Thiophenes; Triazines | 1990 |
Tibenelast, 5,6-diethoxybenzo(B)thiophene-2-carboxylic acid, sodium salt (LY186655), is an orally active anti-asthma compound in the guinea pig.
Topics: Administration, Oral; Airway Resistance; Aminophylline; Anaphylaxis; Animals; Asthma; Bronchodilator Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Guinea Pigs; Injections, Intravenous; Lung Compliance; Male; Molecular Structure; Thiophenes | 1990 |
Immunomodulatory activity of anti-atherogenic drugs: effects on blastogenesis, humoral response, delayed hypersensitivity and passive anaphylaxis by immune complexes.
Topics: Anaphylaxis; Animals; Antibody Formation; Antigen-Antibody Complex; Arteriosclerosis; Clofibrate; Clofibric Acid; Cyclic AMP; Cyclic GMP; Female; Hypersensitivity, Delayed; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Niacin; Thiophenes; Ticlopidine | 1985 |
Immunosuppressive activity of 3-acetyl-5-(4-fluorobenzylidene)-4-hydroxy-2-oxo-2:5-dihydrothiophen (I.C.I. 47,776).
Topics: Anaphylaxis; Animals; Antibody Formation; Cyclophosphamide; Depression, Chemical; Guinea Pigs; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Mice; Rats; Species Specificity; Thioguanine; Thiophenes | 1968 |