Page last updated: 2024-08-18

thiophenes and Amyloid Deposits

thiophenes has been researched along with Amyloid Deposits in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Griffin, P; Kim, DE; Kim, DH; Lee, J; Musiek, ES; Sheehan, PW; Yoon, SY1
Fermigier, A; Hamel, E; Lacalle-Aurioles, M; Royea, J; Trigiani, LJ1
Appelqvist, H; Bäck, M; Cairns, NJ; Klingstedt, T; Nilsson, KPR; Shirani, H1
Baumann, F; Beschorner, N; Blennow, K; Fox, NC; Ghetti, B; Glatzel, M; Hammarström, P; Häsler, LM; Jucker, M; Kaeser, SA; Lashley, T; Mahler, J; Nilsson, KPR; Nyström, S; Oblak, AL; Portelius, E; Rasmussen, J; Sepulveda-Falla, D; Staufenbiel, M; Walker, LC1
Duan, W; Fan, J; Guo, X; Shen, X; Sun, Y; Zhou, T; Zhu, Z1
Binnie, M; McBride, A; Noble, J; Seckl, JR; Sooy, K; Walker, BR; Webster, SP; Yau, JL1
Cui, MC; Li, ZJ; Liu, BL; Tang, RK1
Cui, M; Jia, H; Li, Z; Liu, B; Tang, R1

Other Studies

8 other study(ies) available for thiophenes and Amyloid Deposits

ArticleYear
Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
    Aging cell, 2020, Volume: 19, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; ARNTL Transcription Factors; Cell Line; Circadian Clocks; CLOCK Proteins; Disease Models, Animal; Isoquinolines; Macrophages; Mice; Mice, Knockout; Microglia; Nuclear Receptor Subfamily 1, Group D, Member 1; Plaque, Amyloid; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2Y12; Repressor Proteins; RNA, Small Interfering; Synapses; Thiophenes

2020
AT2R's (Angiotensin II Type 2 Receptor's) Role in Cognitive and Cerebrovascular Deficits in a Mouse Model of Alzheimer Disease.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:6

    Topics: Alzheimer Disease; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Cognition; Disease Models, Animal; Imidazoles; Losartan; Mice; Neuroimmunomodulation; Neurovascular Coupling; Plaque, Amyloid; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sulfonamides; Thiophenes; Vasodilation

2020
Synthesis of Thiophene-Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Dec-01, Volume: 23, Issue:67

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Brain; Fluorescent Dyes; Humans; Ligands; Optical Imaging; Plaque, Amyloid; Protein Aggregates; tau Proteins; Thiophenes

2017
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 12-05, Volume: 114, Issue:49

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Fluorescent Dyes; Frontal Lobe; Gene Expression; Humans; Male; Mice; Occipital Lobe; Peptide Hydrolases; Plaque, Amyloid; Presenilin-1; Protein Aggregates; Protein Binding; Protein Conformation; Proteolysis; Spectrometry, Fluorescence; Temporal Lobe; Thiophenes

2017
Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.
    European journal of pharmacology, 2015, Sep-05, Volume: 762

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cognition; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Lipoproteins; Mice; Mice, Transgenic; Nesting Behavior; Plaque, Amyloid; Retinoid X Receptor alpha; Thiophenes

2015
Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.
    Endocrinology, 2015, Volume: 156, Issue:12

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cerebral Cortex; Cognition; Disease Models, Animal; Humans; Insulysin; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Pyrazoles; Thiophenes

2015
Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for beta-amyloid plaques in Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzothiazoles; Brain; Chromatography, High Pressure Liquid; Female; Injections, Intravenous; Iodine Radioisotopes; Ligands; Mice; Mice, Transgenic; Plaque, Amyloid; Radionuclide Imaging; Radiopharmaceuticals; Solubility; Thiophenes; Tissue Distribution

2010
Novel (E)-5-styryl-2,2'-bithiophene derivatives as ligands for β-amyloid plaques.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Transport; Brain; Contrast Media; Disease Models, Animal; Female; Humans; Iodine Radioisotopes; Ligands; Mice; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Thiophenes; Tomography, Emission-Computed, Single-Photon

2011