thiophenes has been researched along with Alzheimer Disease in 96 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.04) | 18.7374 |
| 1990's | 11 (11.46) | 18.2507 |
| 2000's | 17 (17.71) | 29.6817 |
| 2010's | 48 (50.00) | 24.3611 |
| 2020's | 19 (19.79) | 2.80 |
| Authors | Studies |
|---|---|
| Acharya, A; Govindaraju, T; Ila, H; Murugan, NA; Ramesh, M | 1 |
| Alanazi, MM; Amran, SI; Biswas, S; Chander, S; Das, B; Hadda, TB; Hasan, AH; Jamalis, J; Murugesan, S; Pratama, MRF; Shakya, S | 1 |
| Ahmed, HA; Devlin, P; Ishrat, T; Ismael, S; Liao, FF; McDonald, MP; Salman, M | 1 |
| Bäck, M; Björk, L; Ghetti, B; Klingstedt, T; Lantz, L; Nilsson, KPR; Vidal, R | 1 |
| Barić, D; Fodor, L; Horváth, O; Lasić, Z; Lovrić, MJ; Marinić, Ž; Milašinović, V; Mlakić, M; Molčanov, K; Odak, I; Škorić, I | 1 |
| Ghetti, B; Klingstedt, T; Lantz, L; Nilsson, KPR; Shirani, H; Vidal, R | 1 |
| Björk, L; Klingstedt, T; Nilsson, KPR | 1 |
| Devanand, DP | 1 |
| Jiang, Y; Jin, R; Li, J; Li, Y; Shi, L; Yang, L; Zhong, D | 1 |
| Griffin, P; Kim, DE; Kim, DH; Lee, J; Musiek, ES; Sheehan, PW; Yoon, SY | 1 |
| Almeida, OP; Ford, AH | 1 |
| Klingstedt, T; Lantz, L; Nilsson, KPR; Shirani, H | 1 |
| Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; Shao, J; Shao, ZH; Shasha, Y; Shaw, K; Sheeba, V; Shekar, K; Shen, G; Shen, H; Shen, XD; Shen, Y; Sherrell, PC; Shete, PB; Shi, AX; Shi, J; Shi, JH; Shi, S; Shi, X; Shigeta, Y; Shimbo, A; Shin, E; Sikka, N; Silhavy, TJ; Simanon, N; Simard, S; Simon, J; Simon, M; Simpson, SD; Simundic, AM; Since, M; Singh, B; Singhroy, DN; Sinisterra, OT; Smith, EH; Sobreira, TJP; Solanes, N; Somasundar, Y; Sommerer, C; Sonei, A; Song, B; Song, E; Song, J; Song, M; Song, Y; Soo Lee, M; Sorensen, MD; Sournia-Saquet, A; Spaepen, E; Spirk, D; Srivastava, S; Stancill, JS; Stanczak, PS; Starenki, D; Starr, F; Step, DL; Steubl, D; Stigliani, JL; Stráská, J; Sträter, N; Su, ZZ; Sudano, I; Suen, JY; Suh, HJ; Sui, ZY; Suico, JG; Suleiman, K; Sumon, K; Sun, HB; Sun, J; Sun, L; Sun, LL; Sun, M; Sun, Q; Sun, W; Sun, X; Sun, XF; Sun, Y; Sun, YB; Sun, YH; Sun, YN; Sun, Z; Sunada, K; Suzuki, S; Sylvan, JB; Takala, J; Talla, D; Tamir, Z; Tan, SJ; Tanda, S; Tang, H; Tang, J; Tang, LF; Tang, SJ; Tang, Y; Tao, FB; Tappel, R; Taratkin, M; Teijeira, Á; Tellew, JE; Thomas, AM; Thomas, SG; Thomson, SR; Tian, J; Tie, Y; Tirado, JL; Tolonen, A; Tosato, G; Tronnet, A; Tsai, S; Turtoi, A; Turtoi, E; Tvrdoňová, M; Tyagi, A; Tzou, DT; Uddin Ahmad, Z; Urias, E; Usawachintachit, M; Ustriyana, P; Utsumi, F; Vacca, M; Vaculovič, T; Vaidya, SS; Valentin, A; Valgepea, K; van den Berg, P; van den Bergh, JP; van der Heiden, K; van Gaalen, K; Van Gemert, W; van Haard, PMM; van Hest, JCM; Vecchiarelli, E; Večeřa, Z; Venkatesh, R; Verhaeghe, P; Verhagen, HJ; Vetter, JM; Vieira, D; Vilchez-Tschischke, JP; Villena-Gutierrez, R; Villoslada Terrones, V; Vital-Jacome, M; Voelkl, J; Vogel, K; Vogrin, S; Volke, D; von Bahr, V; Vysloužil, J; Wade, TL; Wagner-Gillespie, M; Walsh, SW; Wan, LJ; Wan, SP; Wang, AL; Wang, B; Wang, BY; Wang, C; Wang, D; Wang, F; Wang, H; Wang, HR; Wang, HY; Wang, J; Wang, JY; Wang, K; Wang, L; Wang, LF; Wang, P; Wang, Q; Wang, R; Wang, SF; Wang, SP; Wang, SR; Wang, T; Wang, W; Wang, WP; Wang, X; Wang, XJ; Wang, Y; Wang, YL; Wang, YN; Wáng, YXJ; Wang, Z; Wang, ZF; Wang, ZY; Waning, B; Warner, JM; Washington, SL; Watson, AK; Wei, B; Wei, C; Wei, F; Wei, X; Wei, Y; Wemhoff, AP; Wen, Z; Weng, TT; Wesdemiotis, C; Wheeler, DA; Wildner, M; Wilson, BK; Wirth, LJ; Wissler, M; Wu, F; Wu, G; Wu, J; Wu, KH; Wu, MC; Wu, P; Wu, PK; Wu, S; Wu, W; Wu, X; Wu, XP; Wu, Y; Wyatt, E; Wyllie, S; Xia, Y; Xiao, BH; Xiao, SZ; Xiao, W; Xiao, X; Xiao, Z; Xie, D; Xie, K; Xie, X; Xie, Y; Xie, YF; Xin, S; Xin, Z; Xing, Q; Xing, WQ; Xiong, D; Xiong, X; Xu, C; Xu, D; Xu, F; Xu, G; Xu, H; Xu, J; Xu, JY; Xu, L; Xu, N; Xu, W; Xu, X; Xu, Y; Xu, YM; Xue, H; Xue, J; Xue, Z; Yan, R; Yan, SQ; Yan, W; Yan, X; Yan, Z; Yang, C; Yang, D; Yang, F; Yang, FC; Yang, G; Yang, J; Yang, M; Yang, P; Yang, Q; Yang, R; Yang, S; Yang, SJ; Yang, TWW; Yang, X; Yang, Y; Yang, Z; Yao, C; Yao, L; Yao, LP; Yao, M; Yao, T; Yao, W; Yao, Y; Yaseen, T; Yazdani, V; Ye, J; Ye, S; Yerys, BE; Yi, HWL; Yi, JL; Yin, F; Yin, J; Yin, Y; Yin, Z; Yong, ZP; Yongli, S; Yoo, JS; Yoshikawa, N; You, Q; Yu, B; Yu, CQ; Yu, H; Yu, HG; Yu, J; Yu, L; Yu, Q; Yu, X; Yu, Y; Yu, YK; Yu, Z; Yuan, Q; Yuan, R; Yuan, W; Yuan, X; Yuan, Y; Zager, RA; Zagozdzon, A; Zaller, N; Zang, YP; Zappi, ME; Zelikoff, JT; Zeman, T; Zhai, X; Zhan, P; Zhang, B; Zhang, C; Zhang, G; Zhang, H; Zhang, HB; Zhang, J; Zhang, JS; Zhang, L; Zhang, M; Zhang, Q; Zhang, RX; Zhang, S; Zhang, T; Zhang, W; Zhang, WH; Zhang, X; Zhang, XX; Zhang, Y; Zhang, YQ; Zhang, YW; Zhang, Z; Zhang, ZH; Zhao, D; Zhao, FL; Zhao, K; Zhao, L; Zhao, M; Zhao, R; Zhao, S; Zhao, W; Zhao, WG; Zhao, X; Zhao, Y; Zheng, G; Zheng, J; Zheng, S; Zheng, W; Zheng, Y; Zheng, YG; Zhong, Z; Zhou, C; Zhou, D; Zhou, H; Zhou, HY; Zhou, L; Zhou, Q; Zhou, X; Zhou, Y; Zhou, YL; Zhou, Z; Zhu, J; Zhu, L; Zhu, N; Zhu, X; Zhu, XF; Zhu, Y; Zhu, Z | 1 |
| Fermigier, A; Hamel, E; Lacalle-Aurioles, M; Royea, J; Trigiani, LJ | 1 |
| Markovic, M; Maroney, M; Stummer, L | 1 |
| Bonnì, S; Caltagirone, C; Casula, EP; Di Lorenzo, F; Ferrari, C; Koch, G; Maiella, M; Martorana, A; Motta, C; Pellicciari, MC; Picazio, S; Ponzo, V; Scaricamazza, E | 1 |
| Cannavò, D; Caraci, F; Caruso, G; Drago, F; Leggio, GM; Salomone, S; Santagati, M | 1 |
| Chen, Y; Du, C; Hong, KH; Liu, Y; Lu, X; Sun, H; Wang, Y; Zhou, Y | 1 |
| Brimson, JM; Malar, DS; Prasanth, MI; Tencomnao, T | 1 |
| Cao, W; Cui, Y; Guan, F; Huang, T; Li, D; Lv, P; Ma, S; Xing, Q; Yang, B; Yang, GL; Zhang, C | 1 |
| Appelqvist, H; Bäck, M; Cairns, NJ; Klingstedt, T; Nilsson, KPR; Shirani, H | 1 |
| Baumann, F; Beschorner, N; Blennow, K; Fox, NC; Ghetti, B; Glatzel, M; Hammarström, P; Häsler, LM; Jucker, M; Kaeser, SA; Lashley, T; Mahler, J; Nilsson, KPR; Nyström, S; Oblak, AL; Portelius, E; Rasmussen, J; Sepulveda-Falla, D; Staufenbiel, M; Walker, LC | 1 |
| Dhananjayan, K; Gunawardena, D; Gyengesi, E; Liang, H; Millington, C; Münch, G; Niedermayer, G; Sirijovski, D; Sonego, S; Venigalla, M | 1 |
| Czubowicz, K; Strosznajder, RP; Wencel, PL; Wójtowicz, S | 1 |
| Bakshi, R; Cahill, CM; Rogers, JT; Wong, A; Xia, N | 1 |
| Burris, TP; Farr, SA; Kermath, BA; Morley, JE; Musiek, ES; Niehoff, M; Roby, DA; Ruiz, F; Voorhees, JR; Zhang, J | 1 |
| Cho, M; Lee, Y; Qin, J | 1 |
| Åslund, KO; Cairns, NJ; Goedert, M; Klingstedt, T; Nilsson, KP; Shirani, H; Sigurdson, CJ | 1 |
| Bagga, P; Biswas, D; Kamal, MA; Rizvi, SM; Shaikh, S; Shakil, S | 1 |
| Matsumoto, J; Nishijo, H; Ono, K; Takamura, Y; Yamada, M | 1 |
| Bonnì, S; Bozzali, M; Caltagirone, C; Di Lorenzo, F; Giacobbe, V; Koch, G; Martorana, A | 1 |
| Aslund, KO; Bäck, M; Gandy, S; Haroutunian, V; Nilsson, KP; Shirani, H; Simon, RA | 1 |
| Dodda, RP; Haque, R; Jadiya, P; Kumar, M; Kumar, V; Modukuri, RK; Nazir, A; Sashidhara, KV; Siddiqi, MI; Sridhar, B | 1 |
| Hashimoto, K | 1 |
| Matera, C; Tata, AM | 1 |
| Deardorff, WJ; Grossberg, GT; Shobassy, A | 1 |
| Goedert, M; Jucker, M; Klingstedt, T; Mahler, J; Nilsson, KP; Nyström, S; Shirani, H; Wegenast-Braun, BM | 1 |
| Duan, W; Fan, J; Guo, X; Shen, X; Sun, Y; Zhou, T; Zhu, Z | 1 |
| Blancafort, L; Hernando, J; Peccati, F; Sodupe, M; Solans-Monfort, X | 1 |
| Binnie, M; McBride, A; Noble, J; Seckl, JR; Sooy, K; Walker, BR; Webster, SP; Yau, JL | 1 |
| Ihara, M; Iikuni, S; Kimura, H; Kitada, A; Matsumura, K; Okamoto, Y; Ono, M; Saji, H; Watanabe, H; Yoshimura, M | 1 |
| Abeijon, P; Caamano, O; Garcia-Mera, X; Gonzalez-Diaz, H; Lopez-Castro, E; Romero-Duran, FJ; Yanez, M | 1 |
| Brorsson, AC; Civitelli, L; Kågedal, K; Khattak, SI; Nelson, E; Sandin, L | 1 |
| Bachhawat, P; Bures, MG; Christopoulos, A; Evans, DA; Felder, CC; Feng, D; Kobilka, BK; Kobilka, TS; Leach, K; Nawaratne, V; Sexton, PM; Sun, B; Thal, DM; Weis, WI | 1 |
| Hu, YH; Ren, WM; Tang, XC; Xu, MM; Zhang, HY | 1 |
| Hajós, GP; Hajós, M; Kelley, C; Koenig, G; Leventhal, L; Nagy, D; Stoiljkovic, M | 1 |
| Claassen, JA; Heerschap, A; Kiliaan, AJ; Roelofs, M; van der Lugt, R; Wiesmann, M | 1 |
| Appelqvist, H; Bäck, M; LeVine, H; Nilsson, KP | 1 |
| Afzal, CM; Hu, J; Li, G; Ma, R; Shen, W; Wang, L; Wang, M; Wang, X; Yao, Y | 1 |
| Abou-Gharbia, M; Antane, M; Aschmies, S; Atchison, K; Chlenov, M; Cole, DC; Comery, T; Diamantidis, G; Ellingboe, J; Fan, K; Galante, R; Gonzales, C; Harrison, B; Ho, DM; Hoke, ME; Hu, Y; Huryn, D; Jacobsen, JS; Jain, U; Jin, M; Kreft, AF; Kremer, K; Kubrak, D; Lin, M; Lu, P; Magolda, R; Martone, R; Mayer, SC; Moore, W; Oganesian, A; Pangalos, MN; Porte, A; Reinhart, P; Resnick, L; Riddell, DR; Sonnenberg-Reines, J; Stock, JR; Sun, SC; Wagner, E; Wang, T; Woller, K; Xu, Z; Zaleska, MM; Zeldis, J; Zhang, M; Zhou, H | 1 |
| Chapman, PF; Hirano, K; Miller, ND; Piers, TM; Rutter, AR; Searle, KL | 1 |
| Abou-Gharbia, M; Adkins, K; Aschmies, S; Atchison, K; Balliet, C; Bard, J; Burczynski, ME; Clarke, DW; Comery, T; Forlow, SB; Frick, G; Gong, X; Gonzales, C; Harrison, B; Huang, X; Huryn, D; Jacobsen, JS; Jin, M; Kreft, A; Leach, MW; Lu, P; Magolda, R; Martone, RL; Mayer, SC; Oganesian, A; Pangalos, MN; Raje, S; Reinhart, PH; Riddell, DR; Sonnenberg-Reines, J; Sun, SC; Wagner, E; Wan, HI; Xu, JZ; Zaleska, MM; Zhou, H | 1 |
| Baralatei, FT; Lauterbach, EC | 1 |
| Tomita, T | 1 |
| Cui, MC; Li, ZJ; Liu, BL; Tang, RK | 1 |
| Domokos, A; Garab, D; Janka, Z; Kálmán, J; Kálmán, S; Pákáski, M; Penke, B; Szabó, G; Szücs, S | 1 |
| Fukushima, T | 1 |
| Cho, YS; Kwon, HJ | 1 |
| Itami, K; Kirchberg, S; Studer, A; Tani, S; Ueda, K; Yamaguchi, J | 1 |
| Fukushima, T; Hattori, H; Hoki, S; Iwakami, N; Nakada, Y; Nakagawa, M; Nakamura, A; Narita, H; Terashima, N; Yamaguchi, H | 1 |
| Cui, M; Jia, H; Li, Z; Liu, B; Tang, R | 1 |
| Inganäs, O; Persson, G; Widengren, J; Wigenius, J | 1 |
| Dahlöf, B; Horiuchi, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Ohshima, K; Sakata, A; Steckelings, UM; Tsukuda, K; Unger, T | 1 |
| Brunhofer, G; Erker, T; Fallarero, A; Guzik, P; Holzgrabe, U; Karlsson, D; Prinz, M; Vuorela, P | 1 |
| Saito, M; Someya, T; Suzuki, Y | 1 |
| Brorsson, AC; Göransson, AL; Kågedal, K; Nilsson, KP | 1 |
| Hopkins, CR | 1 |
| Bernardi, G; Caltagirone, C; Di Lorenzo, F; Esposito, Z; Koch, G; Lo Giudice, T; Martorana, A | 1 |
| Bayraktar, G; Fritschi, SK; Hammarström, P; Jucker, M; Klingstedt, T; Liebig, C; Mahler, J; Mason, JJ; Nilsson, KP; Skodras, A; Wegenast-Braun, BM | 1 |
| Dumin, JA; Loureiro, RM; McKee, TD; Tate, B; Zarayskiy, V | 1 |
| Beher, D; Owens, AP; Shearman, MS; Wrigley, JD | 1 |
| Maubach, K | 1 |
| Bar-Ner, N; Brandeis, R; Egozi, I; Fisher, A; Haring, R; Kliger-Spatz, M; Marcovitch, I; Natan, N; Pittel, Z; Sonego, H | 1 |
| Hirouchi, M | 1 |
| Bacskai, BJ; Hyman, BT; Klunk, WE; Nesterov, EE; Skoch, J; Swager, TM | 1 |
| Chandra, R; Kung, HF; Kung, MP | 1 |
| Chang, YS; Chung, JK; Ganesha, RB; Jeong, JM; Kim, HW; Kim, YJ; Lee, DS; Lee, MC; Lee, YS | 1 |
| Gharibzadeh, S; Hoseini, SS; Mahdavi, S | 1 |
| Camarda, C; Camarda, R; Monastero, R | 1 |
| Münch, G; Palm, D; Riederer, P; Schindler, U; Schinzel, R; Schraven, E; Taneli, Y | 1 |
| Brandeis, R; Fisher, A; Gurwitz, D; Haring, R; Heldman, E; Karton, Y; Marciano, D; Meshulam, H; Pittel, Z; Segall, Y | 1 |
| Barg, Y; Brandeis, R; Fisher, A; Ginzburg, I; Gurwitz, D; Haring, R; Heldman, E; Karton, Y; Klimowsky, S; Korczyn, AD; Marciano, D; Meshulam, H; Pinkas-Kramarski, R; Pittel, Z; Sadot, E; Treves, TA; Verchovsky, R; Vogel, Z | 1 |
| Cunningham, AM; Hipkiss, AR; Mayer, S; Michaelis, J; Müller, R; Münch, G; Neumann, A; Riederer, P; Schinzel, R | 1 |
| Fukunari, A; Kato, A; Nakajima, T; Sakai, Y | 1 |
| Hooper, NM; Hussain, I; Karran, EH; Parvathy, S; Turner, AJ | 1 |
| Retz, W; Riederer, P; Rösler, M; Thome, J | 1 |
| Fisher, A; Fitten, LJ; Halgren, E; O'Neill, J; Ortiz, F; Siembieda, DW | 1 |
| Auguet, M; Chabrier, PE; Demerlé-Pallardy, C | 1 |
| Hooper, NM; Parkin, ET; Trew, AJ; Turner, AJ | 1 |
| Deng, M; Growdon, JH; Nitsch, RM; Schoenfeld, D; Tennis, M | 1 |
| Beach, TG; Fisher, A; Potter, PE; Sue, LI; Walker, DG | 1 |
| Brandeis, R; Fisher, A; Gurwitz, D; Haring, R; Heldman, E; Karton, I; Levy, A; Pittel, Z; Sapir, M | 1 |
| Brandeis, R; Dachir, S; Fisher, A; Grunfeld, Y; Heldman, E; Karton, I; Levy, A; Pittel, Z; Sapir, M | 1 |
| Brandeis, R; Dachir, S; Fisher, A; Heldman, E; Karton, I; Levy, A; Pittel, Z; Sapir, M | 1 |
23 review(s) available for thiophenes and Alzheimer Disease
| Article | Year |
|---|---|
Thiophene-Based Ligands: Design, Synthesis and Their Utilization for Optical Assignment of Polymorphic-Disease-Associated Protein Aggregates.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Fluorescent Dyes; Humans; Ligands; Protein Aggregates; Proteins; Thiophenes | 2023 |
Management of neuropsychiatric symptoms in dementia.
Topics: Alzheimer Disease; Antipsychotic Agents; Apathy; Humans; Quinolones; Thiophenes; United States | 2023 |
AMPK: Potential Therapeutic Target for Alzheimer's Disease.
Topics: Alzheimer Disease; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Autophagy; Biphenyl Compounds; Clinical Trials as Topic; Gene Expression Regulation; Humans; Insulin Resistance; Mitochondria; Neuroprotective Agents; Oxidative Stress; Phosphorylation; Pyrones; Ribonucleotides; tau Proteins; Thiophenes | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
New antipsychotic drugs for the treatment of agitation and psychosis in Alzheimer's disease: focus on brexpiprazole and pimavanserin.
Topics: Alzheimer Disease; Antipsychotic Agents; Anxiety; Humans; Piperidines; Psychotic Disorders; Quinolones; Thiophenes; Urea | 2020 |
The emerging role of the sigma-1 receptor in autophagy: hand-in-hand targets for the treatment of Alzheimer's.
Topics: Alzheimer Disease; Animals; Autophagy; Furans; Humans; Maleates; Molecular Targeted Therapy; Receptors, sigma; Sigma-1 Receptor; Spiro Compounds; Thiazolidines; Thiophenes | 2021 |
Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity.
Topics: 5' Untranslated Regions; Acute Disease; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Down Syndrome; Ferritins; Humans; Iron; Iron-Regulatory Proteins; Lead Poisoning, Nervous System; Manganese Poisoning; Mice; Muscarinic Agonists; Neurons; Protein Biosynthesis; Quinuclidines; Rats; Response Elements; RNA, Messenger; Thiophenes | 2019 |
Pharmacological approaches to targeting muscarinic acetylcholine receptors.
Topics: Alzheimer Disease; Animals; Humans; Muscarinic Agonists; Pyridines; Quinuclidines; Receptors, Muscarinic; Sjogren's Syndrome; Thiadiazoles; Thiophenes | 2014 |
Safety and clinical effects of EVP-6124 in subjects with Alzheimer's disease currently or previously receiving an acetylcholinesterase inhibitor medication.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Clinical Trials, Phase III as Topic; Humans; Nicotinic Agonists; Quinuclidines; Thiophenes | 2015 |
Multi-Target Mining of Alzheimer Disease Proteome with Hansch's QSBR-Perturbation Theory and Experimental-Theoretic Study of New Thiophene Isosters of Rasagiline.
Topics: Alzheimer Disease; Humans; Indans; Models, Theoretical; Neuroprotective Agents; Proteome; Quantitative Structure-Activity Relationship; Thiophenes | 2017 |
Advances in development of fluorescent probes for detecting amyloid-β aggregates.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Boron Compounds; Curcumin; Fluorescent Dyes; Humans; Optical Imaging; Stilbenes; Thiazoles; Thiophenes | 2016 |
[Alzheimer's disease treatment by inhibition/modulation of the gamma-secretase activity].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Clinical Trials as Topic; Drug Design; Enzyme Inhibitors; Humans; Sulfonamides; Tetrahydronaphthalenes; Thiophenes; Valine | 2009 |
[Pharmacological properties of T-817MA, a novel neurotrophic agent, for treatment of Alzheimer's disease.].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Humans; Maleates; Mice; Nerve Growth Factors; Neurites; Neuroprotective Agents; Rats; tau Proteins; Thiophenes | 2010 |
Control of autophagy with small molecules.
Topics: Alzheimer Disease; Autophagy; Cell Death; Humans; Neurodegenerative Diseases; Parkinson Disease; Proteins; Pyrimidinones; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes | 2010 |
GABA(A) receptor subtype selective cognition enhancers.
Topics: Alzheimer Disease; Animals; Benzodiazepines; Cognition; Cognition Disorders; Disease Models, Animal; GABA Agonists; Haplorhini; Hippocampus; Humans; Mice; Mice, Transgenic; Receptors, GABA-A; Thiazoles; Thiophenes | 2003 |
M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cell Death; Disease Models, Animal; Down-Regulation; Humans; Memory Disorders; Mice; Muscarinic Agonists; Oxidative Stress; Piperidines; Quinuclidines; Receptor, Muscarinic M1; Spiro Compounds; tau Proteins; Thiazoles; Thiophenes | 2003 |
[Current status and perspectives on the development of therapeutic agents for Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cholinesterase Inhibitors; Diethylamines; Humans; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Thiophenes | 2004 |
Progress in medicinal chemistry of novel selective muscarinic agonists.
Topics: Acetylcholine; Alzheimer Disease; Animals; Chemistry, Pharmaceutical; Humans; Parasympathomimetics; Protein Conformation; Quinuclidines; Receptors, Muscarinic; Thiophenes | 1993 |
M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update.
Topics: Alzheimer Disease; Animals; Clinical Trials as Topic; GTP-Binding Proteins; Humans; Ligands; Muscarinic Agonists; Nerve Growth Factors; PC12 Cells; Phosphorylation; Pyridines; Quinuclidines; Rats; Receptors, Cholinergic; Signal Transduction; tau Proteins; Thiadiazoles; Thiophenes | 1996 |
Free radicals in Alzheimer's dementia: currently available therapeutic strategies.
Topics: Alzheimer Disease; Antioxidants; Drugs, Chinese Herbal; Free Radical Scavengers; Free Radicals; Humans; Monoamine Oxidase Inhibitors; Neurons; Parkinson Disease; Piperazines; Psychotropic Drugs; Selegiline; Thiophenes; Vitamins | 1998 |
Nitric oxide synthases: targets for therapeutic strategies in neurological diseases.
Topics: Alzheimer Disease; Amidines; Amyotrophic Lateral Sclerosis; Animals; Benzylamines; Brain Injuries; Brain Ischemia; Enzyme Induction; Humans; Huntington Disease; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Nerve Tissue Proteins; Nervous System Diseases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Organ Specificity; Polymethacrylic Acids; Pyrazines; Thiophenes | 1999 |
The role of proteolysis in Alzheimer's disease.
Topics: ADAM Proteins; ADAM17 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Biotinylation; Endopeptidases; Humans; Hydroxamic Acids; Membrane Lipids; Membrane Proteins; Metalloendopeptidases; Nerve Tissue Proteins; Phenylalanine; Presenilin-1; Presenilin-2; Protease Inhibitors; Rats; Thiophenes | 2000 |
AF102B: rational treatment strategy for Alzheimer's disease: recent advances.
Topics: Alzheimer Disease; Humans; Parasympathomimetics; Quinuclidines; Thiophenes | 1990 |
5 trial(s) available for thiophenes and Alzheimer Disease
| Article | Year |
|---|---|
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Effect of Rotigotine vs Placebo on Cognitive Functions Among Patients With Mild to Moderate Alzheimer Disease: A Randomized Clinical Trial.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition; Female; Humans; Male; Mental Status and Dementia Tests; Middle Aged; Nootropic Agents; Tetrahydronaphthalenes; Thiophenes; Treatment Outcome | 2020 |
Dopaminergic modulation of cortical plasticity in Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Dopamine Agonists; Female; Humans; Male; Motor Cortex; Neuronal Plasticity; Phenylcarbamates; Rivastigmine; Tetrahydronaphthalenes; Thiophenes; Transcranial Magnetic Stimulation | 2014 |
Dopamine D₂-agonist rotigotine effects on cortical excitability and central cholinergic transmission in Alzheimer's disease patients.
Topics: Aged; Alzheimer Disease; Cerebral Cortex; Cholinergic Neurons; Dopamine Agonists; Dose-Response Relationship, Drug; GABAergic Neurons; Humans; Middle Aged; Neural Inhibition; Neuronal Plasticity; Nootropic Agents; Receptors, Dopamine D2; Single-Blind Method; Synaptic Transmission; Tetrahydronaphthalenes; Thiophenes; Transcranial Magnetic Stimulation; Transdermal Patch | 2013 |
M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update.
Topics: Alzheimer Disease; Animals; Clinical Trials as Topic; GTP-Binding Proteins; Humans; Ligands; Muscarinic Agonists; Nerve Growth Factors; PC12 Cells; Phosphorylation; Pyridines; Quinuclidines; Rats; Receptors, Cholinergic; Signal Transduction; tau Proteins; Thiadiazoles; Thiophenes | 1996 |
70 other study(ies) available for thiophenes and Alzheimer Disease
| Article | Year |
|---|---|
Thiophene-Based Dual Modulators of Aβ and Tau Aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Drug Evaluation, Preclinical; Humans; Neuroprotective Agents; Protein Aggregates; Small Molecule Libraries; tau Proteins; Thiophenes | 2021 |
Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation.
Topics: Acetylcholinesterase; Alzheimer Disease; Cells, Cultured; Chalcone; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes | 2022 |
Direct AT2R Stimulation Slows Post-stroke Cognitive Decline in the 5XFAD Alzheimer's Disease Mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Humans; Imidazoles; Mice; Mice, Transgenic; Neurodegenerative Diseases; Receptor, Angiotensin, Type 2; Stroke; Sulfonamides; Thiophenes | 2022 |
Proteophenes - Amino Acid Functionalized Thiophene-based Fluorescent Ligands for Visualization of Protein Deposits in Tissue Sections with Alzheimer's Disease Pathology.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Fluorescent Dyes; Humans; Ligands; tau Proteins; Thiophenes | 2022 |
Resveratrol-Maltol and Resveratrol-Thiophene Hybrids as Cholinesterase Inhibitors and Antioxidants: Synthesis, Biometal Chelating Capability and Crystal Structure.
Topics: Alzheimer Disease; Antioxidants; Chelating Agents; Cholinesterase Inhibitors; Cholinesterases; Galantamine; Humans; Ligands; Molecular Docking Simulation; Pyrones; Resveratrol; Structure-Activity Relationship; Thiophenes; Trace Elements | 2022 |
Thiophene-Based Ligands for Histological Multiplex Spectral Detection of Distinct Protein Aggregates in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Humans; Ligands; Protein Aggregates; tau Proteins; Thiophenes | 2023 |
Brexpiprazole (Rexulti) for agitation in Alzheimer's dementia.
Topics: Alzheimer Disease; Antipsychotic Agents; Humans; Psychomotor Agitation; Quinolones; Thiophenes | 2023 |
Inhibition of REV-ERBs stimulates microglial amyloid-beta clearance and reduces amyloid plaque deposition in the 5XFAD mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; ARNTL Transcription Factors; Cell Line; Circadian Clocks; CLOCK Proteins; Disease Models, Animal; Isoquinolines; Macrophages; Mice; Mice, Knockout; Microglia; Nuclear Receptor Subfamily 1, Group D, Member 1; Plaque, Amyloid; Receptors, Cytoplasmic and Nuclear; Receptors, Purinergic P2Y12; Repressor Proteins; RNA, Small Interfering; Synapses; Thiophenes | 2020 |
Are We Getting Better at Managing Agitation in Dementia?
Topics: Alzheimer Disease; Dementia; Double-Blind Method; Humans; Quinolones; Thiophenes | 2020 |
Synthesis and Characterization of Thiophene-based Donor-Acceptor-Donor Heptameric Ligands for Spectral Assignment of Polymorphic Amyloid-β Deposits.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Humans; Ligands; Thiophenes | 2020 |
AT2R's (Angiotensin II Type 2 Receptor's) Role in Cognitive and Cerebrovascular Deficits in a Mouse Model of Alzheimer Disease.
Topics: Alzheimer Disease; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Cognition; Disease Models, Animal; Imidazoles; Losartan; Mice; Neuroimmunomodulation; Neurovascular Coupling; Plaque, Amyloid; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sulfonamides; Thiophenes; Vasodilation | 2020 |
Brexpiprazole in the treatment of schizophrenia and agitation in Alzheimer's disease.
Topics: Alzheimer Disease; Antipsychotic Agents; Humans; Quinolones; Schizophrenia; Thiophenes | 2020 |
Novel BuChE-IDO1 inhibitors from sertaconazole: Virtual screening, chemical optimization and molecular modeling studies.
Topics: Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Isoindoles; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thiophenes | 2021 |
Pharmacological activation of the Nrf2 pathway by 3H-1, 2-dithiole-3-thione is neuroprotective in a mouse model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Disease Models, Animal; Heme Oxygenase-1; Hippocampus; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Thiones; Thiophenes | 2018 |
Synthesis of Thiophene-Based Optical Ligands That Selectively Detect Tau Pathology in Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Brain; Fluorescent Dyes; Humans; Ligands; Optical Imaging; Plaque, Amyloid; Protein Aggregates; tau Proteins; Thiophenes | 2017 |
Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Female; Fluorescent Dyes; Frontal Lobe; Gene Expression; Humans; Male; Mice; Occipital Lobe; Peptide Hydrolases; Plaque, Amyloid; Presenilin-1; Protein Aggregates; Protein Binding; Protein Conformation; Proteolysis; Spectrometry, Fluorescence; Temporal Lobe; Thiophenes | 2017 |
Investigation Into the Effects of Tenilsetam on Markers of Neuroinflammation in GFAP-IL6 Mice.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cerebellum; Chronic Disease; Hippocampus; Humans; Inflammation; Interleukin-6; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Piperazines; Pyruvaldehyde; Thiophenes; Tissue Distribution; Tumor Necrosis Factor-alpha | 2018 |
The role of ceramide and SEW 2871 in the transcription of enzymes involved in amyloid b precursor protein metabolism in an experimental model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Ceramides; Humans; Lysophospholipids; Models, Theoretical; Neurons; Oxadiazoles; PC12 Cells; Rats; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Transcription, Genetic | 2018 |
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Disks Large Homolog 4 Protein; Hippocampus; Male; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Peptide Fragments; Pyrrolidines; Thiophenes | 2019 |
Ultrasensitive Detection of Amyloid-β Using Cellular Prion Protein on the Highly Conductive Au Nanoparticles-Poly(3,4-ethylene dioxythiophene)-Poly(thiophene-3-acetic acid) Composite Electrode.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Biosensing Techniques; Bridged Bicyclo Compounds, Heterocyclic; Electric Conductivity; Electrochemical Techniques; Electrodes; Gold; Metal Nanoparticles; Mice; Polymers; Prion Proteins; Thiophenes | 2019 |
The structural basis for optimal performance of oligothiophene-based fluorescent amyloid ligands: conformational flexibility is essential for spectral assignment of a diversity of protein aggregates.
Topics: Alzheimer Disease; Amyloid; Animals; Brain; Fluorescent Dyes; Mice; Mice, Transgenic; Molecular Structure; Proteins; Structure-Activity Relationship; Thiophenes | 2013 |
Invokana (Canagliflozin) as a dual inhibitor of acetylcholinesterase and sodium glucose co-transporter 2: advancement in Alzheimer's disease- diabetes type 2 linkage via an enzoinformatics study.
Topics: Alzheimer Disease; Animals; Canagliflozin; Cholinesterase Inhibitors; Computer Simulation; Databases, Protein; Diabetes Mellitus, Type 2; Glucosides; Humans; Models, Molecular; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Thiophenes | 2014 |
Effects of the neurotrophic agent T-817MA on oligomeric amyloid-β-induced deficits in long-term potentiation in the hippocampal CA1 subfield.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Atrophy; CA1 Region, Hippocampal; Disease Models, Animal; In Vitro Techniques; Long-Term Potentiation; Male; Maleates; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Neuroprotective Agents; Synapses; Thiophenes | 2014 |
DTB Select: 3 | March 2014.
Topics: Alzheimer Disease; Antibodies, Monoclonal, Murine-Derived; Automobile Driving; Child; Chronic Pain; Clopidogrel; Hepatitis B; Histamine H2 Antagonists; Humans; Hypertension; Practice Guidelines as Topic; Practice Patterns, Physicians'; Proton Pump Inhibitors; Respiratory Tract Infections; Rituximab; Thiophenes; Ticlopidine | 2014 |
Pentameric thiophene-based ligands that spectrally discriminate amyloid-β and tau aggregates display distinct solvatochromism and viscosity-induced spectral shifts.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Humans; Ligands; Luminescent Agents; Optical Imaging; Protein Aggregation, Pathological; tau Proteins; Thiophenes; Viscosity | 2014 |
Benzofuran-chalcone hybrids as potential multifunctional agents against Alzheimer's disease: synthesis and in vivo studies with transgenic Caenorhabditis elegans.
Topics: Acetylcholine; Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Antioxidants; Benzofurans; Binding Sites; Caenorhabditis elegans; Chalcone; Chalcones; Crystallography, X-Ray; Disease Models, Animal; Humans; Microscopy, Fluorescence; Molecular Conformation; Molecular Docking Simulation; Oxidative Stress; Protein Structure, Tertiary; Structure-Activity Relationship; Thiophenes | 2014 |
Tropisetron and its targets in Alzheimer's disease.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Animals; Humans; Indoles; Inflammation; Nicotinic Agonists; Quinuclidines; Serotonin Antagonists; Thiophenes; Tropisetron | 2015 |
Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anions; Brain; Fluorescent Dyes; Humans; Ligands; Luminescent Agents; Mice; Molecular Probes; Neurodegenerative Diseases; Proteins; Thiophenes | 2015 |
Small molecule TBTC as a new selective retinoid X receptor α agonist improves behavioral deficit in Alzheimer's disease model mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cognition; Disease Models, Animal; Gene Expression Regulation; HEK293 Cells; Humans; Lipoproteins; Mice; Mice, Transgenic; Nesting Behavior; Plaque, Amyloid; Retinoid X Receptor alpha; Thiophenes | 2015 |
Disaggregation-induced fluorescence enhancement of NIAD-4 for the optical imaging of amyloid-β fibrils.
Topics: Alzheimer Disease; Amyloid; Binding Sites; Humans; Molecular Dynamics Simulation; Nitriles; Protein Structure, Tertiary; Spectrometry, Fluorescence; Thermodynamics; Thiophenes | 2015 |
Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Cerebral Cortex; Cognition; Disease Models, Animal; Humans; Insulysin; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plaque, Amyloid; Pyrazoles; Thiophenes | 2015 |
Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents That Selectively Detect Neurofibrillary Tangles in Alzheimer's Disease Brains.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzimidazoles; Benzofurans; Benzothiazoles; Benzoxazoles; Brain; Humans; Iodine Radioisotopes; Male; Mice; Neurofibrillary Tangles; Pyridines; Radionuclide Imaging; Radiopharmaceuticals; Stereoisomerism; Structure-Activity Relationship; Styrenes; tau Proteins; Temporal Lobe; Thiophenes | 2015 |
The Luminescent Oligothiophene p-FTAA Converts Toxic Aβ1-42 Species into Nontoxic Amyloid Fibers with Altered Properties.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Humans; Peptide Fragments; Protein Aggregation, Pathological; Protein Stability; Protein Structure, Secondary; Thiophenes | 2016 |
Crystal structures of the M1 and M4 muscarinic acetylcholine receptors.
Topics: Acetylcholine; Allosteric Regulation; Allosteric Site; Alzheimer Disease; Crystallization; Crystallography, X-Ray; Drug Inverse Agonism; Humans; Models, Molecular; Nicotinic Acids; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Schizophrenia; Static Electricity; Substrate Specificity; Surface Properties; Thiophenes; Tiotropium Bromide | 2016 |
Hippocampal network dynamics in response to α7 nACh receptors activation in amyloid-β overproducing transgenic mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Female; Gamma Rhythm; Hippocampus; Male; Mice, Transgenic; Molecular Targeted Therapy; Nerve Net; Quinuclidines; Theta Rhythm; Thiophenes | 2016 |
Angiotensin II, hypertension and angiotensin II receptor antagonism: Roles in the behavioural and brain pathology of a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Blood Pressure; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Imidazoles; Maze Learning; Mice, Transgenic; Spatial Learning; Thiophenes | 2017 |
Anionic Oligothiophenes Compete for Binding of X-34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ.
Topics: Alkenes; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Benzoates; Brain; Humans; Positron-Emission Tomography; Thiazoles; Thiophenes | 2016 |
Protective effect of 3H-1, 2-dithiole-3-thione on cellular model of Alzheimer's disease involves Nrf2/ARE signaling pathway.
Topics: Active Transport, Cell Nucleus; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cytoprotection; Down-Regulation; Gene Expression Regulation; Glutathione; Heme Oxygenase-1; Intracellular Space; Kelch-Like ECH-Associated Protein 1; Malondialdehyde; Mice; Mitochondria; Molecular Targeted Therapy; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Response Elements; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Thiones; Thiophenes | 2017 |
Discovery of begacestat, a Notch-1-sparing gamma-secretase inhibitor for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Mice; Mice, Transgenic; Models, Molecular; Molecular Conformation; Receptor, Notch1; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Thiophenes | 2008 |
Procognitive 5-HT6 antagonists in the rat forced swimming test: potential therapeutic utility in mood disorders associated with Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Cognition; Male; Mood Disorders; Piperazines; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Sulfonamides; Swimming; Thiophenes | 2009 |
Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
Topics: Adolescent; Adult; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Binding, Competitive; Cell Line; CHO Cells; Cricetinae; Cricetulus; Dogs; Enzyme Inhibitors; Fear; Female; Humans; Male; Mice; Mice, Transgenic; Middle Aged; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Sulfonamides; Thiophenes; Young Adult | 2009 |
Switching to duloxetine remits ziprasidone - associated urinary incontinence and improves neuropsychiatric behavior in dementia: possible relationship of incontinence to 5HT2 receptor blockade.
Topics: Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Duloxetine Hydrochloride; Humans; Male; Parkinsonian Disorders; Piperazines; Receptors, Serotonin, 5-HT2; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Thiazoles; Thiophenes; Urinary Incontinence | 2009 |
Synthesis and evaluation of novel benzothiazole derivatives based on the bithiophene structure as potential radiotracers for beta-amyloid plaques in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Autoradiography; Benzothiazoles; Brain; Chromatography, High Pressure Liquid; Female; Injections, Intravenous; Iodine Radioisotopes; Ligands; Mice; Mice, Transgenic; Plaque, Amyloid; Radionuclide Imaging; Radiopharmaceuticals; Solubility; Thiophenes; Tissue Distribution | 2010 |
[The effects of duloxetine on beta-actin stress response in rat brain].
Topics: Actins; Adrenergic Uptake Inhibitors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Duloxetine Hydrochloride; Male; Mitogen-Activated Protein Kinase 1; Neuronal Plasticity; Norepinephrine; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Stress, Psychological; Thiophenes | 2010 |
Oxidative biaryl coupling of thiophenes and thiazoles with arylboronic acids through palladium catalysis: otherwise difficult C4-selective C-H arylation enabled by boronic acids.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Boronic Acids; Carbon; Catalysis; Cyclic N-Oxides; Humans; Hydrogen; Oxidation-Reduction; Palladium; Protease Inhibitors; Stereoisomerism; Thiazoles; Thiophenes | 2011 |
T-817MA, a neuroprotective agent, attenuates the motor and cognitive impairments associated with neuronal degeneration in P301L tau transgenic mice.
Topics: Alzheimer Disease; Animals; Cognition Disorders; Hippocampus; Maleates; Mice; Mice, Transgenic; Movement Disorders; Neuroprotective Agents; Synaptophysin; tau Proteins; Thiophenes | 2011 |
Novel (E)-5-styryl-2,2'-bithiophene derivatives as ligands for β-amyloid plaques.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biological Transport; Brain; Contrast Media; Disease Models, Animal; Female; Humans; Iodine Radioisotopes; Ligands; Mice; Mice, Transgenic; Peptide Fragments; Plaque, Amyloid; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Thiophenes; Tomography, Emission-Computed, Single-Photon | 2011 |
Interactions between a luminescent conjugated oligoelectrolyte and insulin during early phases of amyloid formation.
Topics: Alzheimer Disease; Amyloid; Electrolytes; Humans; Insulin; Luminescence; Microscopy, Electron; Nanofibers; Nanotechnology; Polymers; Protein Folding; Spectrometry, Fluorescence; Thiophenes | 2011 |
Direct stimulation of angiotensin II type 2 receptor enhances spatial memory.
Topics: Alzheimer Disease; Animals; Blood Pressure; Brain; Cells, Cultured; Cerebrovascular Circulation; Cognition; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Neurites; Neurons; Receptor, Angiotensin, Type 2; RNA, Messenger; Sulfonamides; Synaptic Potentials; Thiophenes | 2012 |
Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Line; Cell Survival; Cholinesterase Inhibitors; Drug Evaluation, Preclinical; Electrophorus; Horses; Humans; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Targeted Therapy; Recombinant Proteins; Small Molecule Libraries; Structure-Activity Relationship; Thiophenes | 2012 |
Delirium associated with duloxetine in a depressed patient with Alzheimer's dementia.
Topics: Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Delirium; Depressive Disorder; Duloxetine Hydrochloride; Female; Humans; Thiophenes | 2012 |
Identification of distinct physiochemical properties of toxic prefibrillar species formed by Aβ peptide variants.
Topics: Acetates; Alzheimer Disease; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Cell Line; Fluorescent Dyes; Humans; Microscopy, Electron, Transmission; Peptide Fragments; Thiophenes | 2012 |
ACS chemical neuroscience molecule spotlight on Begacestat (GSI-953).
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Sulfonamides; Thiophenes | 2012 |
Spectral discrimination of cerebral amyloid lesions after peripheral application of luminescent conjugated oligothiophenes.
Topics: Alzheimer Disease; Amyloid; Animals; Blood-Brain Barrier; Brain; Humans; Immunohistochemistry; Luminescence; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Staining and Labeling; Thiophenes | 2012 |
An improved cell-based method for determining the γ-secretase enzyme activity against both Notch and APP substrates.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Azepines; Cell Line; Enzyme Inhibitors; Humans; Oxadiazoles; Receptors, Notch; Solid Phase Extraction; Substrate Specificity; Sulfonamides; Thiophenes | 2013 |
Generation of C-terminally truncated amyloid-beta peptides is dependent on gamma-secretase activity.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Antibodies, Monoclonal; Antibody Specificity; Aspartic Acid Endopeptidases; Cell Line; Culture Media, Conditioned; Endopeptidases; Enzyme Activation; Enzyme Inhibitors; Fluorobenzenes; Humans; Kidney; Mass Spectrometry; Metalloendopeptidases; Molecular Sequence Data; Neuroblastoma; Pentanoic Acids; Peptide Fragments; Peptides; Phenylalanine; Recombinant Proteins; Thiophenes; Transfection | 2002 |
In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers.
Topics: Alzheimer Disease; Amyloid; Animals; Brain; Diagnostic Imaging; Fluorescent Dyes; Mice; Molecular Structure; Nitriles; Spectrometry, Fluorescence; Thiophenes | 2005 |
Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Drug Design; Ligands; Mice; Molecular Structure; Structure-Activity Relationship; Thiophenes | 2006 |
Synthesis and evaluation of benzothiophene derivatives as ligands for imaging beta-amyloid plaques in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Fluorine Radioisotopes; Humans; Isotope Labeling; Ligands; Radionuclide Imaging; Radiopharmaceuticals; Thiophenes | 2006 |
Oltipraz may be useful in the prevention or treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Humans; Mice; Neurodegenerative Diseases; Oxidative Stress; Pyrazines; Schistosomicides; Thiones; Thiophenes | 2007 |
Potential drug-drug interaction between duloxetine and acenocoumarol in a patient with Alzheimer's disease.
Topics: Acenocoumarol; Alzheimer Disease; Anticoagulants; Drug Interactions; Duloxetine Hydrochloride; Female; Humans; International Normalized Ratio; Middle Aged; Selective Serotonin Reuptake Inhibitors; Thiophenes | 2007 |
The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation.
Topics: Aging; Alzheimer Disease; Cognition Disorders; Glycation End Products, Advanced; Glycosylation; Humans; Macromolecular Substances; Nerve Tissue Proteins; Piperazines; Psychotropic Drugs; Thiophenes | 1994 |
Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Carnosine; Cognition; Cross-Linking Reagents; Fructose; Glycation End Products, Advanced; Guanidines; Humans; Memory; Neuropeptide Y; Particle Size; Peptide Fragments; Piperazines; Protein Structure, Secondary; Solubility; Temperature; Thiazoles; Thiophenes | 1997 |
Prevention of amyloid-like deposition by a selective prolyl endopeptidase inhibitor, Y-29794, in senescence-accelerated mouse.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Hippocampus; Ketones; Male; Mice; Prolyl Oligopeptidases; Protease Inhibitors; Serine Endopeptidases; Thiophenes | 1997 |
Alzheimer's amyloid precursor protein alpha-secretase is inhibited by hydroxamic acid-based zinc metalloprotease inhibitors: similarities to the angiotensin converting enzyme secretase.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Drug Screening Assays, Antitumor; Endopeptidases; Enzyme Inhibitors; Humans; Hydroxamic Acids; Metalloendopeptidases; Microvilli; Neuroblastoma; Peptidyl-Dipeptidase A; Phenylalanine; Swine; Tetrazolium Salts; Thiophenes; Tumor Cells, Cultured; Zinc | 1998 |
Reduction of motoric agitation and restlessness by AF102B and tacrine in the macaque.
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; Macaca radiata; Male; Motor Activity; Muscarinic Agonists; Pilot Projects; Psychomotor Agitation; Quinuclidines; Tacrine; Thiophenes | 1999 |
The selective muscarinic M1 agonist AF102B decreases levels of total Abeta in cerebrospinal fluid of patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Female; Humans; Male; Quinuclidines; Thiophenes | 2000 |
Reduction of cerebrospinal fluid amyloid beta after systemic administration of M1 muscarinic agonists.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Cerebrospinal Fluid; Female; Muscarinic Agonists; Neurons; Peptide Fragments; Piperidines; Quinuclidines; Rabbits; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiazoles; Thiophenes | 2001 |
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Avoidance Learning; Binding, Competitive; Cognition Disorders; Copper; Disease Models, Animal; Male; Memory; Mice; Motor Activity; Parasympathomimetics; Pilocarpine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Thiophenes | 1991 |
(+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3') quinuclidine (AF102B): a new M1 agonist attenuates cognitive dysfunctions in AF64A-treated rats.
Topics: Alzheimer Disease; Animals; Aziridines; Behavior, Animal; Choline; Cognition Disorders; Disease Models, Animal; Drug Design; Male; Molecular Structure; Parasympathomimetics; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thiophenes | 1989 |