thiophanate has been researched along with Dicrocoeliasis* in 3 studies
3 other study(ies) available for thiophanate and Dicrocoeliasis
Article | Year |
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Efficacy of thiophanate and albendazole against natural infections of Dicrocoelium dentriticum, Fasciola hepatica, and gastrointestinal nematodes and cestodes in sheep.
The anthelmintic efficacy of thiophanate and albendazole was compared in sheep with heavy infestations of Dicrocoelium dentriticum. The effectiveness of each drug was determined by counting the numbers of D. dentriticum in animals killed 21 days after treatment. In one group, the dose of thiophanate recommended for use against gastrointestinal (GI) nematodes (50 mg kg-1 live weight) was found to be 74.4% effective against D. dentriticum. Two tablets (each containing 76 mg of active ingredient) of albendazole per 30 kg live weight were given to a second group and the dose repeated after 1 week. Under this regime, albendazole was found to be 12.7% effective against D. dentriticum. The effect of each drug on other parasites was as follows; thiophanate had no effect against Fasciola hepatica or cestodes, while albendazole was 71.5% effective against F. hepatica and 100% effective against cestodes. Both drugs were highly effective against GI nematodes. Topics: Albendazole; Animals; Carbamates; Cestode Infections; Dicrocoeliasis; Fasciola hepatica; Fascioliasis; Feces; Female; Helminthiasis; Helminthiasis, Animal; Nematode Infections; Parasite Egg Count; Sheep; Sheep Diseases; Thiophanate | 1990 |
Treatment of Dicrocoelium dendriticum with a combination of thiophanate and brotianide.
Topics: Animals; Anthelmintics; Benzamides; Carbamates; Dicrocoeliasis; Dicrocoelium; Drug Combinations; Oxyclozanide; Sheep; Sheep Diseases; Tetramisole; Thiophanate | 1988 |
[Pharmacokinetics and anti-Dicrocoelium activity of thiophanate and its major metabolite in ruminants].
After a single oral dosage of 40 mg thiophanate/kg in cattle, sheep and goats, the parent compound and its main metabolite: ethyl benzimidazol-1H-yl-2-carbamate (EBC) are evidenced in plasma by HPLC analysis for 60 to 72 hours. The rate of metabolic change of thiophanate into EBC is 34% in sheep, 52% in goats and 57% in cattle. At this dosage, thiophanate seems to be effective against Dicrocoelium in sheep. On the contrary, EBC is uneffective at 15 mg/kg while it seems undetectable in plasma at any time. Topics: Animals; Benzimidazoles; Carbamates; Cattle; Cattle Diseases; Dicrocoeliasis; Female; Goats; Ruminants; Sheep; Sheep Diseases; Thiophanate | 1988 |