thiopental and Myotonia

thiopental has been researched along with Myotonia* in 1 studies

Reviews

1 review(s) available for thiopental and Myotonia

ArticleYear
[Anesthesia in myotonia].
    Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8, Issue:5

    Myotonia is defined as a persistent contraction of skeletal muscles after their stimulation. This contracture is not prevented or relieved by regional anaesthesia or muscle relaxants. The sensitivity to non-depolarizing muscle relaxants is usually normal. Suxamethonium, neostigmine, hypothermia, a rise in kalaemia should be avoided. There have been case reports of malignant hyperthermia in patients with myotonia congenita. Dystrophia myotonica is the second most frequent of the inherited muscle diseases, after Duchenne's dystrophy. The severity of the disease is due more to the muscular atrophy and the multiple organ involvement than to the abnormal contraction. Atrioventricular heart block and dysrhythmias are more common than heart failure. Prolonged apnoea and pneumonia are the main risks of anaesthesia. In severe cases, exists a restrictive respiratory insufficiency which is preceded by a fall in the maximum expiratory pressure. Dysphagias and inefficient coughing may occur early. An increased susceptibility to hypnotic drugs and opiates is a common feature. Spontaneous sleep apnoeas should be sought before anaesthesia, especially by using pulse oximetry. The anaesthetic implications are reemphasized.

    Topics: Anesthesia; Contracture; Disease Susceptibility; Female; Humans; Hypercapnia; Male; Malignant Hyperthermia; Myotonia; Neostigmine; Neuromuscular Nondepolarizing Agents; Succinylcholine; Thiopental

1989