thiopental and Laryngeal-Diseases

Topics: Anesthetics, Local; Benperidol; Blood Circulation; Female; Fentanyl; Humans; Intubation, Intratracheal; Laryngeal Diseases; Laryngoscopy; Lidocaine; Male; Microsurgery; Middle Aged; Premedication; Propanidid; Reflex; Surgical Procedures, Operative; Tetracaine; Thiopental

Topics: Aged; Airway Obstruction; Anesthesia, Intravenous; Female; Hemorrhage; Humans; Intubation, Intratracheal; Laryngeal Diseases; Laryngoscopy; Lidocaine; Phenylephrine; Thiopental

Topics: Adult; Anesthesia, Inhalation; Dacryocystitis; Diabetes Mellitus, Type 1; Female; Humans; Laryngeal Diseases; Postoperative Complications; Respiration; Sarcoidosis; Succinylcholine; Thiopental

Serum thiopentone (S-Thiop) was estimated every 10 minutes using a new high performance liquid chromatographic method during fentanyl-bolus-complemented (0.01 mg) thiopentone infusion anaesthesia (bolus of 5 mg/kg, infusion dosis 23.7 mg/min) for laryngo-microscopic procedures. Before stopping the infusion after 18/17 min (SD 8/5) (male/female) S-Thiop was (mean (SD) range) 16.0/12.4 (4.6/5.7) 5.9-26.8/5.1-26.6 mg/l; after stop of the infusion 12.8/10.5 (4.5/5.3) 7.6-25.5/4.5-23.4 mg/l. Patients reacted to verbal command after 11.5 (10.3) 11-81 min. There were no clinically relevant correlations between S-Thiop and frontal EMG and compressed 1-channel-EEG (ABM, Datex, Helsinki), nor with data recorded during recovery. Reasons may be: the total depolarisation block caused by succinylcholine; the method of compressing the EEG; subjective influences on the recording of recovery data; sampling in intervals of 10 min instead of at certain points of the anaesthesia course. We still recommend this total i.v.-anaesthesia for the short time endolaryngeal procedures need; before using this method for longer periods additional pharmacokinetic studies should be performed.

Topics: Adult; Aged; Anesthesia, Intravenous; Arousal; Electroencephalography; Electromyography; Evoked Potentials; Facial Muscles; Female; Humans; Laryngeal Diseases; Male; Middle Aged; Thiopental

Topics: Adolescent; Adult; Aged; Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Laryngeal Diseases; Laser Therapy; Middle Aged; Thiopental

Topics: Adult; Aged; Anesthesia, General; Atropine; Carbon Dioxide; Female; Humans; Hydrogen-Ion Concentration; Laryngeal Diseases; Laryngeal Neoplasms; Laryngoscopy; Male; Meperidine; Microsurgery; Middle Aged; Oxygen; Positive-Pressure Respiration; Succinylcholine; Thiopental; Ventilators, Mechanical

Topics: Barbiturates; Humans; Laryngeal Diseases; Laryngismus; Larynx; Spasm; Thiopental