thiopental and Astrocytoma

thiopental has been researched along with Astrocytoma* in 3 studies

Trials

1 trial(s) available for thiopental and Astrocytoma

Article	Year
Transcranial Doppler monitoring during induction of anesthesia: effects of propofol, thiopental, and hyperventilation in patients with large malignant brain tumors. Journal of neurosurgical anesthesiology, 1993, Volume: 5, Issue:2 Disturbed autoregulation and CO2 reactivity have been reported in patients with brain tumors. Therefore, we decided to monitor the cerebrovascular effects of anesthetic drugs and hyperventilation. Transcranial Doppler sonography (TCD) can measure noninvasively alterations of flow velocities (v) and cross-sectional vessel area (VA) in large brain arteries. Twenty-eight patients with large malignant brain tumors in the territory of the middle cerebral artery (MCA) randomly received propofol or thiopental for induction and maintenance of anesthesia. Mean arterial pressure (MAP), heart rate (HR), and TCD parameters (vMCA and VA of the tumor or nontumor side) were determined at six data points (DP). The first measurements (MAP, HR, and TCD of the nontumor side) were performed before (DP I) and 60 s after (DP II) induction of anesthesia with either 2 mg/kg propofol or 4 mg/kg thiopental. After intubation and normoventilation (50% O2 in air), 0.05-0.1 mg/kg midazolam and an alfentanil infusion (100 micrograms/kg x h) were initiated. Then MAP, HR, vMCA, and VA of the tumor side were analyzed before (DP III) and 60 s after (DP IV) either propofol (1 mg/kg) or thiopental (2 mg/kg) were given. Finally, the effects of hyperventilation on HR, MAP, vMCA, and VA (tumor side) were determined (DP V and VI). Mean +/- SD, thiopental or propofol reactivity (non-tumor and tumor side) and CO2 reactivity (tumor side) were calculated; statistical comparison between DP I and II, III and IV, and V and VI was performed by paired t tests (p < 0.05). Unpaired t tests were used to evaluate differences between groups.(ABSTRACT TRUNCATED AT 250 WORDS) Topics: Adult; Anesthesia, General; Astrocytoma; Brain Neoplasms; Female; Glioma; Hemodynamics; Humans; Hyperventilation; Male; Middle Aged; Monitoring, Intraoperative; Propofol; Thiopental; Ultrasonography	1993

Article

Year

Transcranial Doppler monitoring during induction of anesthesia: effects of propofol, thiopental, and hyperventilation in patients with large malignant brain tumors.

Journal of neurosurgical anesthesiology, 1993, Volume: 5, Issue:2

Disturbed autoregulation and CO2 reactivity have been reported in patients with brain tumors. Therefore, we decided to monitor the cerebrovascular effects of anesthetic drugs and hyperventilation. Transcranial Doppler sonography (TCD) can measure noninvasively alterations of flow velocities (v) and cross-sectional vessel area (VA) in large brain arteries. Twenty-eight patients with large malignant brain tumors in the territory of the middle cerebral artery (MCA) randomly received propofol or thiopental for induction and maintenance of anesthesia. Mean arterial pressure (MAP), heart rate (HR), and TCD parameters (vMCA and VA of the tumor or nontumor side) were determined at six data points (DP). The first measurements (MAP, HR, and TCD of the nontumor side) were performed before (DP I) and 60 s after (DP II) induction of anesthesia with either 2 mg/kg propofol or 4 mg/kg thiopental. After intubation and normoventilation (50% O2 in air), 0.05-0.1 mg/kg midazolam and an alfentanil infusion (100 micrograms/kg x h) were initiated. Then MAP, HR, vMCA, and VA of the tumor side were analyzed before (DP III) and 60 s after (DP IV) either propofol (1 mg/kg) or thiopental (2 mg/kg) were given. Finally, the effects of hyperventilation on HR, MAP, vMCA, and VA (tumor side) were determined (DP V and VI). Mean +/- SD, thiopental or propofol reactivity (non-tumor and tumor side) and CO2 reactivity (tumor side) were calculated; statistical comparison between DP I and II, III and IV, and V and VI was performed by paired t tests (p < 0.05). Unpaired t tests were used to evaluate differences between groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Topics: Adult; Anesthesia, General; Astrocytoma; Brain Neoplasms; Female; Glioma; Hemodynamics; Humans; Hyperventilation; Male; Middle Aged; Monitoring, Intraoperative; Propofol; Thiopental; Ultrasonography

1993

Other Studies

2 other study(ies) available for thiopental and Astrocytoma

Article	Year
The EEG as a test of the effect of thiopental after brain tumours. Electroencephalography and clinical neurophysiology, 1969, Volume: 26, Issue:2 Topics: Astrocytoma; Basal Ganglia; Brain Neoplasms; Electroencephalography; Glioma; Humans; Oligodendroglioma; Radiography; Spinal Neoplasms; Thiopental	1969
[Electroencephalographic studies on the influence of radiotherapy of cerebral tumors on the effect of thiopental in humans]. Der Anaesthesist, 1969, Volume: 18, Issue:3 Topics: Adult; Astrocytoma; Brain; Brain Neoplasms; Electroencephalography; Female; Glioblastoma; Glioma; Humans; Male; Oligodendroglioma; Thiopental; Ultraviolet Therapy	1969