thionicotinamide has been researched along with Colorectal-Neoplasms* in 1 studies
1 other study(ies) available for thionicotinamide and Colorectal-Neoplasms
Article | Year |
---|---|
Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.
Targeting mutant KRAS signaling pathways continues to attract attention as a therapeutic strategy for KRAS-driven tumors. In this study, we exploited the power of the CRISPR-Cas9 system to identify genes affecting the tumor xenograft growth of human mutant KRAS (KRAS Topics: ATPases Associated with Diverse Cellular Activities; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; CRISPR-Cas Systems; DNA Helicases; DNA-Binding Proteins; Fructokinases; Genome-Wide Association Study; HCT116 Cells; Humans; Mutation; Niacinamide; Phosphotransferases (Alcohol Group Acceptor); Protein Subunits; Proto-Oncogene Proteins p21(ras); Xenograft Model Antitumor Assays | 2017 |