thioinosine and Hemolysis

thioinosine has been researched along with Hemolysis* in 1 studies

Other Studies

1 other study(ies) available for thioinosine and Hemolysis

ArticleYear
Captopril and 6-mercaptopurine: whose SH possesses higher antioxidant ability?
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:12

    Antioxidant capacities of captopril (CAP), 6-mercaptopurine (6-MP) and 9-(beta-D-ribofuranosyl)-6-mercaptopurine (6-MPR) were investigated by interacting them with 2,2'-diphenyl-1-picrylhydrazyl (DPPH), galvinoxyl radical, and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) cation radical (ABTS(+)(*)), and by protecting DNA and erythrocyte against 2,2'-azobis(2-amidinopropane hydrochloride) (AAPH) induced oxidation. It was found that CAP possessed the highest ability to donate the hydrogen atom in -SH to DPPH and galvinoxyl, while 6-MPR had the strongest ability to reduce ABTS(+)(*). In the process of protecting DNA and erythrocytes against AAPH-induced oxidation, CAP can trap 0.5 and 1.3 radicals, 6-MP can trap 0.6 and 2.2, and 6-MPR can trap 1.0 and 3.0 radicals, respectively. CAP can also protect erythrocytes against hemin-induced hemolysis.

    Topics: Antioxidants; Captopril; Erythrocytes; Free Radical Scavengers; Hemin; Hemolysis; Humans; Mercaptopurine; Molecular Structure; Sulfhydryl Compounds

2009