thioguanine-anhydrous and Sarcoma--Myeloid

thioguanine-anhydrous has been researched along with Sarcoma--Myeloid* in 2 studies

Other Studies

2 other study(ies) available for thioguanine-anhydrous and Sarcoma--Myeloid

Article	Year
Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement. Leukemia & lymphoma, 2003, Volume: 44, Issue:9 Granulocytic sarcoma (extramedullary myelosarcoma, chloroma) is a rare extramedullary myeloid tumor which can occur at any anatomical site as isolated finding or associated with acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS). In this case, we describe a 71-year-old man who presented with incomplete paresis of the left arm, periorbital swelling, a maculopapular exanthema and organ involvement including testis and stomach. The tumors responded to combination chemotherapy and the patient fully recovered. However, after five months the patient relapsed and died quickly. This case confirms the importance of including granulocytic sarcoma in the differential diagnoses of a variety of diseases. In AML, the presence of granulocytic sarcoma is associated with worse overall survival. When diagnosed, it should be treated with intensive chemotherapy as soon as possible. Topics: Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Arm; Biomarkers, Tumor; Carboxylic Ester Hydrolases; Cerebral Hemorrhage; Cytarabine; Daunorubicin; Exanthema; Fatal Outcome; Humans; Leukosialin; Male; Mitoxantrone; Neoplasm Proteins; Paresis; Sarcoma, Myeloid; Sialoglycoproteins; Skin; Stomach; Testis; Thioguanine; Vimentin	2003
Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9). Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:8 T(8;9) is a relatively new translocation that has been reported in a few patients with chronic myeloid leukemia (CML) but never in acute myeloid leukemia (AML). We report here a patient who presented with AML with t(8; 9). He lacked the Philadelphia chromosome but tested positive for the gene by the polymerase chain reaction method. This confirmed the diagnosis of CML with blast crisis, and appropriate treatment could be instituted Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Child, Preschool; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Ethmoid Sinus; Etoposide; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myeloid, Accelerated Phase; Male; Meninges; Mitoxantrone; Remission Induction; Sacrococcygeal Region; Sarcoma, Myeloid; Thioguanine; Translocation, Genetic	2002

Article

Year

Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement.

Leukemia & lymphoma, 2003, Volume: 44, Issue:9

Granulocytic sarcoma (extramedullary myelosarcoma, chloroma) is a rare extramedullary myeloid tumor which can occur at any anatomical site as isolated finding or associated with acute myelogenous leukemia (AML) or myelodysplastic syndrome (MDS). In this case, we describe a 71-year-old man who presented with incomplete paresis of the left arm, periorbital swelling, a maculopapular exanthema and organ involvement including testis and stomach. The tumors responded to combination chemotherapy and the patient fully recovered. However, after five months the patient relapsed and died quickly. This case confirms the importance of including granulocytic sarcoma in the differential diagnoses of a variety of diseases. In AML, the presence of granulocytic sarcoma is associated with worse overall survival. When diagnosed, it should be treated with intensive chemotherapy as soon as possible.

Topics: Aged; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Arm; Biomarkers, Tumor; Carboxylic Ester Hydrolases; Cerebral Hemorrhage; Cytarabine; Daunorubicin; Exanthema; Fatal Outcome; Humans; Leukosialin; Male; Mitoxantrone; Neoplasm Proteins; Paresis; Sarcoma, Myeloid; Sialoglycoproteins; Skin; Stomach; Testis; Thioguanine; Vimentin

2003

Blast crisis of chronic myeloid leukemia: diagnosis prompted by T(8;9).

Journal of pediatric hematology/oncology, 2002, Volume: 24, Issue:8

T(8;9) is a relatively new translocation that has been reported in a few patients with chronic myeloid leukemia (CML) but never in acute myeloid leukemia (AML). We report here a patient who presented with AML with t(8; 9). He lacked the Philadelphia chromosome but tested positive for the gene by the polymerase chain reaction method. This confirmed the diagnosis of CML with blast crisis, and appropriate treatment could be instituted

Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Child, Preschool; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Combined Modality Therapy; Cytarabine; Daunorubicin; Ethmoid Sinus; Etoposide; Fusion Proteins, bcr-abl; Humans; Karyotyping; Leukemia, Myeloid, Accelerated Phase; Male; Meninges; Mitoxantrone; Remission Induction; Sacrococcygeal Region; Sarcoma, Myeloid; Thioguanine; Translocation, Genetic

2002