thioguanine-anhydrous and Cat-Diseases

Cats frequently develop a variety of spontaneous hemolymphatic noeplasias. Long-term remissions in the nonlymphatic leukemic cat are difficult to obtain; therefore, more successful chemotherapeutic agents are sought for disease control. The purpose in the present study is to describe the clinical investigation of 3 antineoplastic drugs given to 23 normal cats. The cats tolerated doxorubican given at the dose level of 30 mg/m2 of body surface area once every 3 weeks; daunomycin, 15 to 30 mg/m2 once every 3 weeks; and 6-thioguanine, 25 mg/m2 for 5 days every 20 to 30 days.

Topics: Alopecia; Animals; Cat Diseases; Cats; Daunorubicin; Doxorubicin; Female; Leukocyte Count; Leukopenia; Male; Thioguanine; Thrombocytopenia

Topics: Animals; Blood Transfusion; Cat Diseases; Cats; Cytarabine; Lymphatic Diseases; Male; Prednisone; Remission, Spontaneous; Thioguanine