Page last updated: 2024-08-22

thioflavin t and Tauopathies

thioflavin t has been researched along with Tauopathies in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (60.00)29.6817
2010's4 (26.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Bastone, A; Cantù, L; Cimini, S; Colombo, L; De Luigi, A; Del Favero, E; Ricci, C; Rossi, G; Russo, L; Salmona, M; Tagliavini, F1
Kasho, K; Krasauskas, L; Morozova-Roche, LA; Smirnovas, V; Stojkovič, G; Wanrooij, S1
Callaway, K; Dobson, CM; Mandelkow, E; Mandelkow, EM; McConlogue, L; Neumann, T; Pickhardt, M; Schenk, D; Schwizer, D; St George-Hyslop, P; Tóth, G; Vendruscolo, M1
Bulic, B; Mandelkow, E; Mandelkow, EM; Pickhardt, M; Schmidt, B; Waldmann, H1
Cassell, MD; Ding, SL; Poremba, A; Van Hoesen, GW1
Haddix, T; Lee, VM; Nakashima-Yasuda, H; Robinson, J; Trojanowski, JQ; Uryu, K1
Bresjanac, M; Kovacs, GG; Mohorko, N; Popović, M; Repovs, G1
Hayashi, S; Ihara, M; Kimura, H; Matsumura, K; Mori, H; Okamoto, Y; Ono, M; Saji, H; Takahashi, R1
Bellmann, C; Giasson, BI; Horiguchi, T; Ischiropoulos, H; Lee, VM; LightFoot, R; Richter-Landsberg, C; Trojanowski, JQ; Uryu, K1
Dabir, D; Forman, MS; Goldbaum, O; Handschuh, M; Lee, VM; Oppermann, M; Richter-Landsberg, C; Trojanowski, JQ; Zhang, B1
Chirita, CN; Kuret, J; Necula, M1
Champy, P; Duyckaerts, C; Féger, J; Hirsch, EC; Höglinger, GU; Khondiker, ME; Lannuzel, A; Lombes, A; Medja, F; Michel, PP; Oertel, WH; Prigent, A; Ruberg, M1
Biernat, J; Gazova, Z; Khlistunova, I; Mandelkow, E; Mandelkow, EM; Pickhardt, M; von Bergen, M; Wang, Y1
Arnold, SE; Chatterjee, A; Clark, CM; Coslett, HB; Farmer, J; Forman, MS; Grossman, M; Hurtig, HI; Johnson, JK; Karlawish, JH; Lee, VM; Miller, BL; Rosen, HJ; Trojanowski, JQ; Van Deerlin, V1
Coksezen, A; Khlistunova, I; Larbig, G; Mandelkow, E; Mandelkow, EM; Meyer, B; Pickhardt, M; Schmidt, B1

Reviews

1 review(s) available for thioflavin t and Tauopathies

ArticleYear
Development of tau aggregation inhibitors for Alzheimer's disease.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:10

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Databases, Factual; Humans; tau Proteins; Tauopathies; Thiazoles

2009

Other Studies

14 other study(ies) available for thioflavin t and Tauopathies

ArticleYear
Biochemical and biophysical features of disease-associated tau mutants V363A and V363I.
    Biochimica et biophysica acta. Proteins and proteomics, 2022, 03-01, Volume: 1870, Issue:3

    Topics: Benzothiazoles; Brain; Heparin; Humans; Molecular Structure; Mutation; Oligonucleotides; Protein Aggregates; Protein Conformation; Scattering, Small Angle; tau Proteins; Tauopathies

2022
Human Polymerase δ-Interacting Protein 2 (PolDIP2) Inhibits the Formation of Human Tau Oligomers and Fibrils.
    International journal of molecular sciences, 2021, May-28, Volume: 22, Issue:11

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Brain; Humans; Nuclear Proteins; tau Proteins; Tauopathies

2021
Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies.
    Current Alzheimer research, 2015, Volume: 12, Issue:9

    Topics: Animals; Benzothiazoles; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluorescent Dyes; High-Throughput Screening Assays; Humans; Mice; Microarray Analysis; Microscopy, Fluorescence; Molecular Structure; Neuroprotective Agents; Protein Aggregates; Protein Multimerization; tau Proteins; Tauopathies; Thiazoles

2015
Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers.
    The Journal of comparative neurology, 2009, Jun-20, Volume: 514, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antigens, Nuclear; Benzothiazoles; Female; Histocytochemistry; Humans; Immunohistochemistry; Male; Nerve Tissue Proteins; Plant Lectins; Pyramidal Cells; Receptors, N-Acetylglucosamine; Tauopathies; Temporal Lobe; Thiazoles

2009
Burden of neurodegenerative diseases in a cohort of medical examiner subjects.
    Journal of forensic sciences, 2010, Volume: 55, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; alpha-Synuclein; Alzheimer Disease; Atrophy; Benzothiazoles; Brain; Brain Edema; Cohort Studies; Coroners and Medical Examiners; Female; Forensic Pathology; Frontotemporal Lobar Degeneration; Humans; Hygiene; Ill-Housed Persons; Immunohistochemistry; Male; Malnutrition; Middle Aged; Neurofibrillary Tangles; Neuropil Threads; Plaque, Amyloid; Staining and Labeling; Tauopathies; Thiazoles; Young Adult

2010
Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples.
    Journal of neuropathology and experimental neurology, 2010, Volume: 69, Issue:4

    Topics: Alzheimer Disease; Benzothiazoles; Brain Diseases; Curcumin; Humans; Neurofibrillary Tangles; Neurons; Pick Disease of the Brain; Silver Staining; Supranuclear Palsy, Progressive; tau Proteins; Tauopathies; Thiazoles

2010
Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer's brains.
    ACS chemical neuroscience, 2011, May-18, Volume: 2, Issue:5

    Topics: Alzheimer Disease; Animals; Autoradiography; Benzothiazoles; Brain; Humans; Iodine Radioisotopes; Mice; Neurofibrillary Tangles; Positron-Emission Tomography; Radiopharmaceuticals; Recombinant Proteins; Rhodanine; Tauopathies; Thiazoles; Thiohydantoins; Tissue Distribution

2011
Nitration of tau protein is linked to neurodegeneration in tauopathies.
    The American journal of pathology, 2003, Volume: 163, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Basal Ganglia; Benzothiazoles; Cell Line; Cerebral Cortex; Down Syndrome; Female; Fluorescent Dyes; Humans; Male; Middle Aged; Nerve Degeneration; Neurodegenerative Diseases; Neurofibrillary Tangles; Nitrates; Pick Disease of the Brain; tau Proteins; Tauopathies; Thiazoles; Tissue Distribution

2003
Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Oct-01, Volume: 23, Issue:26

    Topics: alpha-Crystallin B Chain; Benzothiazoles; Brain; Cell Line; Cysteine Endopeptidases; Cytoskeleton; Enzyme Inhibitors; Fluorescent Dyes; Humans; Immunohistochemistry; Inclusion Bodies; Leupeptins; Microtubules; Multienzyme Complexes; Okadaic Acid; Oligodendroglia; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Phosphatase 2; tau Proteins; Tauopathies; Thiazoles

2003
Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.
    Biochemistry, 2005, Aug-02, Volume: 44, Issue:30

    Topics: Benzothiazoles; Binding, Competitive; Carbocyanines; Humans; Kinetics; Models, Chemical; Nerve Tissue Proteins; Protein Processing, Post-Translational; Solubility; tau Proteins; Tauopathies; Thiazoles

2005
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.
    Journal of neurochemistry, 2005, Volume: 95, Issue:4

    Topics: alpha-Synuclein; Amyloid beta-Peptides; Analysis of Variance; Animals; Antineoplastic Combined Chemotherapy Protocols; Behavior, Animal; Benzothiazoles; Body Weight; Caspase 3; Caspases; Cell Death; Cerebral Cortex; Cytarabine; Diagnostic Imaging; Dopamine and cAMP-Regulated Phosphoprotein 32; Doxorubicin; Dystonia; Electron Transport Complex III; Enzyme Activation; Glial Fibrillary Acidic Protein; Immunohistochemistry; Locomotion; Male; Microscopy, Electron, Transmission; Mitochondria; Neurons; Phosphopyruvate Hydratase; Phosphorylation; Posture; Psychomotor Performance; Rats; Rats, Inbred Lew; Rotenone; tau Proteins; Tauopathies; Thiazoles; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase; Ubiquitin; Uncoupling Agents

2005
Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs.
    The Journal of biological chemistry, 2006, Jan-13, Volume: 281, Issue:2

    Topics: Alzheimer Disease; Amino Acid Motifs; Benzothiazoles; Brain; Cell Line; Cell Line, Tumor; Centrifugation, Density Gradient; Chromatography; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Humans; Mass Spectrometry; Microscopy, Electron; Microscopy, Fluorescence; Models, Biological; Models, Chemical; Mutation; Neurons; Peptide Hydrolases; Phosphorylation; Plasmids; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; tau Proteins; Tauopathies; Thiazoles; Thrombin; Time Factors

2006
Frontotemporal dementia: clinicopathological correlations.
    Annals of neurology, 2006, Volume: 59, Issue:6

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Benzothiazoles; Brain; Dementia; Diagnosis, Differential; Female; Humans; Immunohistochemistry; Inclusion Bodies; Male; Middle Aged; Neurodegenerative Diseases; Neuropsychological Tests; Tauopathies; Thiazoles; Ubiquitin

2006
Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells.
    Biochemistry, 2007, Sep-04, Volume: 46, Issue:35

    Topics: Animals; Benzothiazoles; Binding Sites; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Humans; Hydrazines; Hydro-Lyases; Ligands; Models, Biological; Models, Chemical; Neurofibrillary Tangles; Protein Binding; Protein Denaturation; Protein Structure, Tertiary; tau Proteins; Tauopathies; Thiazoles

2007