thioflavin t has been researched along with Disease Models, Animal in 74 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.35) | 18.7374 |
1990's | 1 (1.35) | 18.2507 |
2000's | 33 (44.59) | 29.6817 |
2010's | 32 (43.24) | 24.3611 |
2020's | 7 (9.46) | 2.80 |
Authors | Studies |
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Haratake, M; Hori, M; Mori, H; Nakayama, M; Ono, M; Tomiyama, T | 1 |
Hur, MG; Kim, SW; Min, JJ; Park, JH; Park, SH; Park, YD; Yang, SD; Yoo, YJ; Yoon, YJ | 1 |
Aguirre, C; Baba, K; Choong, CJ; Doi, J; Goto, Y; Hideshima, M; Ikenaka, K; Kakuda, K; Kimura, Y; Mochizuki, H; Nabekura, K; Nagai, Y; Nagano, S; Nakajima, K; Takeuchi, T; Yamaguchi, K | 1 |
Hagimori, M; Haratake, Y; Minaki, K; Mukai, T; Munekane, M; Sano, K; Tsuchiya, M; Yamasaki, T | 1 |
Nair, AV; Ran, C; Ran, K; Yang, J; Zhu, B | 1 |
Girigoswami, A; Girigoswami, K; Metkar, SK; Vijayashree, R | 1 |
Genov, M; Hummel, T; Kasture, A; Krenn, L; Moloney, M; Pretsch, A; Pretsch, D; Rollinger, JM; Schmid, A; Wöhrer, T | 1 |
Kim, Y; Lee, H; Park, S; Shin, J | 1 |
Alijanvand, SH; Burdukiewicz, M; Christensen, LFB; Dueholm, MS; Herbst, FA; Kjeldal, H; Otzen, DE | 1 |
Ackermann, M; Denver, P; Kelly, P; Konerding, MA; Mitchell, CA; Satchell, SC | 1 |
Eriksen, JL; Georgiou, P; Gould, TD; Jarvela, TS; Lindberg, I; Womack, T | 1 |
Gao, Y; He, X; Liu, Q; Xu, F; Xu, L; Zheng, N | 1 |
Johnstone, DM; Marotte, L; Purushothuman, S; Stone, J; Stowe, S | 1 |
Georgopoulos, S; Klinakis, A; Paouri, E; Sesele, K; Thanopoulou, K; Tsefou, E | 1 |
Duncker, DJ; Gorsse-Bakker, C; Krabbendam-Peters, I; Sneep, S; Uitterdijk, A; van Beusekom, HM; van der Giessen, WJ; van Duin, RW | 1 |
Bongarzone, ER; Cantuti-Castelvetri, L; Celej, MS; Claycomb, KI; Crocker, SJ; Gallea, JI; Givogri, MI; Li, G; Lopez-Rosas, A; Marshall, MS; Santos, MB; Smith, BR; van Breemen, R | 1 |
Fitzgerald, S; Lauer, SL; Levy, E; Lopez-Guzman, M; Nixon, RA; Schoen, C; Wilson, DA; Xu, W | 1 |
Bartic, C; Benilova, I; Castillo Cano, V; De Strooper, B; Gallardo, R; Ramakers, M; Rousseau, F; Schymkowitz, J; Snellinx, A; Ungureanu, AA | 1 |
Hatou, S; Inagaki, E; Ogawa, Y; Shimmura, S; Tsubota, K; Yamazoe, K; Yasuda, M; Yoshida, S | 1 |
Moir, RD; Moore, A; Ran, C; Ross, AW; Sun, H; Tanzi, RE; Tian, X; Tian, Y; Zhang, C; Zhang, X | 1 |
Bodi, V; Bonanad, C; Chorro, FJ; de Dios, E; Forteza, MJ; Hervas, A; Miñana, G; Nuñez, J; Perez-Sole, N; Ruiz-Sauri, A | 1 |
Lahiri, DK; Paule, MG; Ray, B; Raymick, J; Sarkar, S; Schmued, L | 1 |
Choi, B; Crouzet, C; Lo, P; Vasilevko, V | 1 |
Alberi, L; Alina Raio, N; Brai, E | 1 |
Ashe, KH; Borchelt, DR; Forster, CL; Hemmy, LS; Huang, ES; Kuskowski, MA; Liu, P; McNellis, BM; Rao, ER; Reichl, JH; Vassar, R; Zahs, KR | 1 |
Etienne, MA; Gordon, M; Hammer, RP; Li, Q; Morgan, D | 1 |
Csernansky, JG; Deal, C; Dong, H; Mace, AG; Martin, MV; Yoo, HS; Yuede, CM | 1 |
Beach, TG; Castaño, EM; Daugs, ID; Davis, J; Esh, CL; Kalback, WM; Kokjohn, TA; Lue, LF; Luehrs, DC; Patton, RL; Roher, AE; Van Nostrand, WE; Van Vickle, GD; Walker, DG | 1 |
Levine, H; Walker, LC | 1 |
Kellaway, LA; Kotwal, GJ; Kulkarni, AP; Pillay, NS | 1 |
Kovacs, B; Lumayag, S; Mufson, EJ; Perez, SE; Xu, S | 1 |
Arai, H; Fujiwara, H; Gamoh, S; Hashimoto, M; Katakura, M; Miyazawa, T; Shahdat, HM; Shido, O; Shimada, T; Tanabe, Y; Yamashita, S | 1 |
Bero, AW; Csernansky, JG; Dong, H; Holtzman, DM; Kling, MJ; Timson, BF; Yuede, CM; Zimmerman, SD | 1 |
Lundmark, K; Westermark, GT; Westermark, P | 1 |
Cook, J; DeArmond, SJ; Lemus, A; Mastrianni, JA; Rassbach, B; Yang, W | 1 |
Bowles, N; Gaspar, RC; Hepler, RW; Joyce, JG; Shughrue, PJ; Villarreal, SA | 1 |
Anan, M; Hara, H; Kataoka, S; Mutoh, T; Tabira, T; Ueda, A | 1 |
Huang, W; Lei, H; Wang, X; Xu, W; Zhan, Y; Zhang, S | 1 |
Borbon, IA; Erickson, RP | 1 |
Arendt, T; Brückner, MK; Hoyer, S; Osmanovic-Barilar, J; Riederer, P; Salkovic-Petrisic, M | 1 |
Ansciaux, E; Burtea, C; Larbanoix, L; Laurent, S; Mahieu, I; Muller, RN; Vander Elst, L | 1 |
Georgopoulos, S; Katsouri, L | 1 |
Chamberlain, R; Curran, GL; Garwood, M; Hultman, KL; Jack, CR; Marjańska, M; Poduslo, JF; Preboske, GM; Wengenack, TM | 1 |
Cardoso, I; Costa, R; Crowther, DC; Speretta, E | 1 |
Borkowski, AH; Landreth, GE; Levy, E; Nixon, RA; Wesson, DW; Wilson, DA | 1 |
Bartnik, D; Brener, O; Funke, SA; Liu, H; Nagel-Steger, L; Sehl, T; Wiesehan, K; Willbold, D | 1 |
Ke, YN; Li, AL; Li, JH; Li, XL; Shi, ZX; Wang, Y; Yang, P | 1 |
Han, H; Kim, HY; Kim, Y; Lee, YS; Roh, EJ; Seo, JH; Shin, KJ | 1 |
Beker, S; Kellner, V; Kerti, L; Stern, EA | 1 |
Borchelt, DR; Coonfield, M; Copeland, NG; Fromholt, D; Gonzales, V; Jenkins, NA; Wang, J; Xu, G | 1 |
Aronow, BJ; Bales, KR; DeMattos, RB; Harmony, JA; Holtzman, DM; O'dell, MA; Parsadanian, M; Paul, SM; Taylor, JW | 1 |
Bacskai, BJ; Games, D; Hyman, BT; Kajdasz, ST; McLellan, ME; Schenk, D; Seubert, P | 1 |
Capsoni, S; Cattaneo, A; Giannotta, S | 1 |
Ashe, KH; Cruz, L; Duff, K; Hyman, BT; Irizarry, MC; Le, R; Sanders, J; Stanley, HE; Urbanc, B | 1 |
Allen, B; Atzori, C; Craxton, M; Crowther, RA; Emson, PC; Ghetti, B; Goedert, M; Holzer, M; Ingram, E; Jakes, R; Migheli, A; Smith, MJ; Spillantini, MG; Takao, M; Virdee, K; Yoshida, H | 1 |
Borowski, BJ; Curran, GL; Jack, CR; Macura, SI; Poduslo, JF; Sigurdsson, EM; Wengenack, TM; Wisniewski, T | 1 |
Bacskai, BJ; D'Amore, JD; Hyman, BT; Kajdasz, ST; McLellan, ME; Stern, EA | 1 |
Bacskai, BJ; Hyman, BT; Kajdasz, ST; McLellan, ME | 1 |
Dudal, S; Gervais, F; Krzywkowski, P; Lacombe, D; Morissette, C; Paquette, J; Tremblay, P | 1 |
Larry Sparks, D | 1 |
Barbour, R; Bard, F; Bussière, T; Buttini, M; Games, D; Grajeda, H; Guido, T; Khan, K; Schenk, D; Seubert, P | 1 |
Bales, KR; Costa, DA; Nilsson, LN; Paul, SM; Potter, H | 1 |
Alfonso, A; Burnam, L; Hoener, M; Liu, L; Perier, C; Przedborski, S; Rodrigues, CM; Saha, S; Sluder, A; Steer, C; Ved, R; Westlund, B; Wolozin, B | 1 |
Adriany, G; Borowski, BJ; Curran, GL; Garwood, M; Holasek, SS; Jack, CR; Lin, J; Poduslo, JF; Preboske, GM; Reyes, DA; Wengenack, TM | 1 |
Gong, Y; Hughes, JA; King, MA; Klein, RL; Meyer, EM; Meyers, CA | 1 |
Glogar, D; Mayr, H; Mohl, W; Sochor, H; Weber, H | 1 |
Bales, KR; Fagan, AM; Holtzman, DM; Mackey, B; McKeel, D; Olney, J; Parsadanian, M; Paul, SM; Sartorius, LJ; Tenkova, T; Wozniak, D | 1 |
Bacskai, BJ; Christie, RH; Hyman, BT; Kajdasz, ST; Webb, WW; Williams, RM; Zipfel, WR | 1 |
Duff, K; La Francois, J; Matsuoka, Y; Picciano, M | 1 |
Bales, KR; Cummins, DJ; DeLong, CA; Esterman, MA; Fishman, CE; Hanson, JC; Jordan, WH; Paul, SM; White, SL | 1 |
Akagi, T; Hashikawa, T; Kikuchi, N; Matsuda, K; Murayama, M; Murayama, O; Nakao, S; Park, JM; Sato, S; Sun, X; Takashima, A; Tanemura, K; Yamaguchi, H; Yoshiike, Y | 1 |
Mallory, M; Mante, M; Masliaha, E; Rockenstein, E; Sisk, A | 1 |
Geula, C; Nagykery, N; Wu, CK | 1 |
Ciebieda, I; Denys, A; Ferszt, T; Korczak, E | 1 |
74 other study(ies) available for thioflavin t and Disease Models, Animal
Article | Year |
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Structure-activity relationship of chalcones and related derivatives as ligands for detecting of beta-amyloid plaques in the brain.
Topics: Alzheimer Disease; Animals; Binding, Competitive; Brain; Chalcones; Disease Models, Animal; Ligands; Mice; Plaque, Amyloid; Structure-Activity Relationship | 2007 |
Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Fluorescence; Fluorescent Dyes; Humans; Mice; Mice, Transgenic; Plaque, Amyloid; Pyridazines; Sensitivity and Specificity; Spectrometry, Fluorescence; Staining and Labeling | 2012 |
Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease.
Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antiparkinson Agents; Benzothiazoles; Biological Assay; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Drug Repositioning; HeLa Cells; High-Throughput Screening Assays; Humans; Mice, Inbred C57BL; Neurons; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Spectrometry, Fluorescence; Tannins | 2022 |
Development of a radioiodinated thioflavin-T-Congo-red hybrid probe for diagnosis of systemic amyloidosis.
Topics: Amyloidosis; Animals; Autoradiography; Benzothiazoles; Congo Red; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Development; Female; Iodine Radioisotopes; Mice; Mice, Inbred ICR; Molecular Structure; Radiopharmaceuticals; Structure-Activity Relationship | 2022 |
CRANAD-28: A Robust Fluorescent Compound for Visualization of Amyloid Beta Plaques.
Topics: Alzheimer Disease; Animals; Benzothiazoles; Boron Compounds; Brain; Curcumin; Disease Models, Animal; Female; Fluorescent Dyes; Humans; Mice; Mice, Transgenic; Microglia; Microscopy, Confocal; Microtomy; Plaque, Amyloid; Staining and Labeling | 2020 |
Attenuation of subcutaneous insulin induced amyloid mass in vivo using Lumbrokinase and Serratiopeptidase.
Topics: Animals; Benzothiazoles; Congo Red; Disease Models, Animal; Endopeptidases; Injection Site Reaction; Injections, Subcutaneous; Insulin; Male; Microscopy, Fluorescence; Microscopy, Polarization; Peptide Hydrolases; Plaque, Amyloid; Protein Aggregation, Pathological; Rats; Rats, Wistar; Subcutaneous Tissue | 2020 |
Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
Topics: Aging; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Benzothiazoles; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Clioquinol; Disease Models, Animal; Emodin; Gene Knockdown Techniques; Homeostasis; Metallothionein; Metals; Neuroprotective Agents; Parkinson Disease; Quercetin; Signal Transduction | 2020 |
Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; Phosphorylation; Piperazines; Protein Aggregates; Protein Conformation, beta-Strand; tau Proteins | 2021 |
Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild-type rats.
Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Animals; Bacterial Proteins; Benzothiazoles; Biofilms; Disease Models, Animal; Endopeptidase K; Feces; Female; Formates; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; Microbial Consortia; Parkinson Disease; Protein Aggregates; Rats; Rats, Transgenic; Urea | 2021 |
Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Benzothiazoles; Capillaries; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Exploratory Behavior; Intussusception; Kidney Glomerulus; Liver; Male; Memory, Short-Term; Mice, Transgenic; Microvessels; Plaque, Amyloid; Spleen; Thiazoles | 2017 |
7B2 chaperone knockout in APP model mice results in reduced plaque burden.
Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Clusterin; Disease Models, Animal; Female; Genotype; Heterozygote; Humans; Memory; Mice, Inbred C57BL; Mice, Knockout; Neuroendocrine Secretory Protein 7B2; Plaque, Amyloid; Solubility; Transgenes | 2018 |
Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer's Disease.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Disease Models, Animal; Fluorescence; Fluorescent Antibody Technique; Mice; Mice, Transgenic; Optical Imaging; Plaque, Amyloid; Presenilin-1; Silver Staining; Staining and Labeling; Ultraviolet Rays | 2019 |
The response of cerebral cortex to haemorrhagic damage: experimental evidence from a penetrating injury model.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Benzothiazoles; Brain; Brain Injuries; Cell Death; Cerebral Cortex; Congo Red; Disease Models, Animal; Female; Ferrocyanides; Heme; Hemorrhage; Hippocampus; Humans; Immunohistochemistry; Male; Neocortex; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins; Temporal Lobe; Thiazoles; Wounds, Penetrating | 2013 |
Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Gliosis; Humans; Integrases; Membrane Glycoproteins; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Phenotype; Presenilin-1; Thiazoles | 2013 |
Serial measurement of hFABP and high-sensitivity troponin I post-PCI in STEMI: how fast and accurate can myocardial infarct size and no-reflow be predicted?
Topics: Animals; Benzothiazoles; Biomarkers; Coronary Circulation; Disease Models, Animal; Fatty Acid-Binding Proteins; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Necrosis; No-Reflow Phenomenon; Predictive Value of Tests; Risk Factors; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Troponin I; Up-Regulation | 2013 |
Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
Topics: alpha-Synuclein; Animals; Benzothiazoles; Brain; Case-Control Studies; Cognition; Disease Models, Animal; Fluorescent Dyes; Humans; Leukodystrophy, Globoid Cell; Lewy Bodies; Mice; Motor Activity; Mutation; Neurons; Psychosine; Thiazoles | 2014 |
Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Benzothiazoles; Disease Models, Animal; Entorhinal Cortex; Female; Habituation, Psychophysiologic; Hippocampus; Male; Memory; Mice, Transgenic; Odorants; Olfactory Bulb; Olfactory Pathways; Piriform Cortex; Thiazoles | 2014 |
The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzothiazoles; Brain; Cell Culture Techniques; Cell Line; Cricetinae; Disease Models, Animal; Humans; Kinetics; Mice; Mice, Inbred C57BL; Mutagenesis; Mutation; Neurons; Peptide Fragments; Solubility; Thermodynamics; Thiazoles | 2014 |
Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2.
Topics: Alleles; Animals; Base Sequence; Benzothiazoles; Corneal Dystrophies, Hereditary; Disease Models, Animal; DNA Primers; DNA, Complementary; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Microscopy, Electron; Microtubule-Associated Proteins; Mutation; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Transforming Growth Factor beta1 | 2015 |
Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Carbon-13 Magnetic Resonance Spectroscopy; Disease Models, Animal; Drug Monitoring; Fluorescent Dyes; Humans; Mice, Transgenic; Molecular Imaging; Photons; Presenilin-1; Proton Magnetic Resonance Spectroscopy; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared; Thiazoles; Tissue Extracts; Titrimetry | 2015 |
Intracoronary Infusion of Thioflavin-S to Study Microvascular Obstruction in a Model of Myocardial Infarction.
Topics: Animals; Benzothiazoles; Coronary Angiography; Coronary Circulation; Coronary Occlusion; Coronary Vessels; Disease Models, Animal; Fluorescent Dyes; Infusions, Intra-Arterial; Microcirculation; Microvessels; Myocardial Infarction; Myocardial Reperfusion Injury; Photography; Sus scrofa; Swine; Thiazoles; Ultraviolet Rays | 2015 |
Oral Administration of Thioflavin T Prevents Beta Amyloid Plaque Formation in Double Transgenic AD Mice.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Benzothiazoles; Brain; Disease Models, Animal; Female; Male; Mice, Transgenic; Microglia; Neuroprotective Agents; Peptide Fragments; Plaque, Amyloid; Thiazoles | 2015 |
Visualization of microbleeds with optical histology in mouse model of cerebral amyloid angiopathy.
Topics: Animals; Benzothiazoles; Carbocyanines; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Fluorescent Dyes; Genetic Predisposition to Disease; Imaging, Three-Dimensional; Mice, Transgenic; Microcirculation; Microscopy, Confocal; Microvessels; Optical Imaging; Plaque, Amyloid; Staining and Labeling; Thiazoles | 2016 |
Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Benzothiazoles; Biomarkers; Blotting, Western; Cell Line, Tumor; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Humans; Immunohistochemistry; Liver; Male; Mice; Middle Aged; Plaque, Amyloid; Receptor, Notch1; tau Proteins; Thiazoles | 2016 |
Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice.
Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Humans; Male; Mice, Transgenic; Plaque, Amyloid; Species Specificity; Thiazoles | 2017 |
Contrasting in vivo effects of two peptide-based amyloid-beta protein aggregation inhibitors in a transgenic mouse model of amyloid deposition.
Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Microglia; Molecular Structure; Peptides; Plaque, Amyloid; Thiazoles | 2008 |
Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Benzothiazoles; Corticosterone; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Mutation; Plaque, Amyloid; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Stress, Psychological; Thiazoles | 2008 |
Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Benzothiazoles; Cerebral Amyloid Angiopathy; Dimerization; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Conformation; Thiazoles | 2008 |
Molecular polymorphism of Abeta in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Binding Sites; Binding, Competitive; Coloring Agents; Congo Red; Diagnostic Imaging; Disease Models, Animal; Humans; Ligands; Molecular Probes; Pathology, Molecular; Plaque, Amyloid; Predictive Value of Tests; Protein Isoforms; Thiazoles | 2010 |
Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test.
Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Association Learning; Behavior, Animal; Benzothiazoles; Complement System Proteins; Conditioning, Psychological; Disease Models, Animal; Genotype; Injections; Maze Learning; Mice; Mice, Transgenic; Reversal Learning; Space Perception; Thiazoles; Viral Proteins | 2008 |
Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Differentiation; Benzothiazoles; Choline O-Acetyltransferase; Disease Models, Animal; Electroretinography; Female; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Presenilin-1; Retina; Retinal Diseases; Syntaxin 1; Thiazoles | 2009 |
Docosahexaenoic acid disrupts in vitro amyloid beta(1-40) fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer's disease model rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies; Benzothiazoles; Cerebral Cortex; Cholesterol; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hippocampus; Microscopy, Electron, Transmission; Neurofibrillary Tangles; Peptide Fragments; Rats; Rats, Wistar; Thiazoles | 2008 |
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Memory; Memory Disorders; Mice; Mice, Transgenic; Organ Size; Peptide Fragments; Physical Conditioning, Animal; Protease Nexins; Random Allocation; Receptors, Cell Surface; Recognition, Psychology; Thiazoles; Time Factors | 2009 |
Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model.
Topics: Amyloid; Amyloidosis; Animals; Benzothiazoles; Coloring Agents; Congo Red; Disease Models, Animal; Female; Humans; Inflammation; Mice; Peptides; Spleen; Thiazoles; Time Factors | 2009 |
A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.
Topics: Animals; Ataxia; Benzothiazoles; Blotting, Western; Brain; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Gerstmann-Straussler-Scheinker Disease; Humans; Kaplan-Meier Estimate; Mice; Mice, Transgenic; Mutation, Missense; Phenotype; Prion Proteins; Prions; PrPC Proteins; PrPSc Proteins; Thiazoles; Time Factors | 2009 |
Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Biotin; Disease Models, Animal; Humans; Immunohistochemistry; Islet Amyloid Polypeptide; Ligands; Male; Mice; Mice, Transgenic; Microscopy, Atomic Force; Molecular Weight; Peptide Fragments; Plaque, Amyloid; Thiazoles | 2010 |
The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Antipsychotic Agents; Benzothiazoles; Bone Marrow Cells; Calcium-Binding Proteins; Cell Culture Techniques; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Drugs, Chinese Herbal; Flow Cytometry; Gene Expression Regulation; Humans; Ki-67 Antigen; Macrophages; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Thiazoles | 2010 |
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA1 Region, Hippocampal; Creatine; Disease Models, Animal; Down-Regulation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Nerve Degeneration; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Thiazoles | 2010 |
Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Peptide Fragments; Plaque, Amyloid; Proteins; Regression Analysis; Thiazoles | 2011 |
Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibiotics, Antineoplastic; Benzothiazoles; Cerebral Amyloid Angiopathy; Disease Models, Animal; Disease Progression; Longitudinal Studies; Male; Peptide Fragments; Rats; Rats, Wistar; Staining and Labeling; Streptozocin; Thiazoles | 2011 |
Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Biotinylation; Blood-Brain Barrier; Contrast Media; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Kinetics; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Molecular Targeted Therapy; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Library; Peptides, Cyclic; Plaque, Amyloid; Protein Binding; Sequence Analysis, DNA; Thiazoles | 2011 |
Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Apolipoproteins E; Astrocytes; Benzothiazoles; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Microglia; Neuroglia; Plaque, Amyloid; Protein Processing, Post-Translational; Receptors, LDL; Thiazoles | 2011 |
Targeting vascular amyloid in arterioles of Alzheimer disease transgenic mice with amyloid β protein antibody-coated nanoparticles.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Arterioles; Benzothiazoles; Disease Models, Animal; Ferric Compounds; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Nanoparticles; Peptide Fragments; Plaque, Amyloid; Platelet Endothelial Cell Adhesion Molecule-1; Thiazoles | 2011 |
Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Anti-Bacterial Agents; Benzothiazoles; Caspase 3; Cell Line, Tumor; Disease Models, Animal; Doxycycline; Drosophila melanogaster; Fluorescent Dyes; Humans; Longevity; Thiazoles | 2011 |
Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Behavioral Symptoms; Benzoates; Benzothiazoles; Benzylamines; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Fourier Analysis; Habituation, Psychophysiologic; Humans; Mice; Mice, Transgenic; Odorants; Olfactory Pathways; Sensation Disorders; Smell; Thiazoles | 2011 |
Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Cell Line, Tumor; Centrifugation, Density Gradient; Disease Models, Animal; Genetic Therapy; Humans; Mice; Nephelometry and Turbidimetry; Neurons; Peptides; Sequence Analysis, DNA; Thiazoles | 2012 |
The preventive effect of garlicin on a porcine model of myocardial infarction reperfusion no-reflow.
Topics: Allyl Compounds; Animals; Benzothiazoles; Cardiotonic Agents; Contrast Media; Disease Models, Animal; Disulfides; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; No-Reflow Phenomenon; Swine; Swine, Miniature; Thiazoles; Ultrasonography | 2014 |
Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid.
Topics: Amyloid beta-Peptides; Animals; Benzene Derivatives; Benzothiazoles; Cells, Cultured; Coumaric Acids; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Molecular Structure; Molecular Weight; Peptide Fragments; Resveratrol; Stilbenes; Thiazoles | 2012 |
Interaction between amyloid-β pathology and cortical functional columnar organization.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Benzothiazoles; Brain Mapping; Disease Models, Animal; Electron Transport Complex IV; Humans; Mice; Mice, Transgenic; Models, Neurological; Mutation; Neural Pathways; Plaque, Amyloid; Presenilin-1; Somatosensory Cortex; Thiazoles | 2012 |
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.
Topics: Amino Acid Substitution; Animals; Benzothiazoles; Binding Sites; Copper; Disease Models, Animal; Female; Histidine; Humans; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Neuron Disease; Motor Neurons; Mutation, Missense; Nerve Tissue Proteins; Neurofibrils; Protein Folding; Spinal Cord; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Thiazoles | 2002 |
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Clusterin; Disease Models, Animal; Glycoproteins; Mice; Mice, Knockout; Molecular Chaperones; Neurites; Peptide Fragments; Plaque, Amyloid; Thiazoles | 2002 |
Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.
Topics: Administration, Topical; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antibodies; Benzothiazoles; Brain; Disease Models, Animal; Fluorescent Dyes; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunotherapy; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Phagocytosis; Plaque, Amyloid; Thiazoles | 2002 |
Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoantibodies; Benzothiazoles; Brain; Cerebellum; Disease Models, Animal; Locus Coeruleus; Mice; Mice, Transgenic; Neostriatum; Nerve Growth Factor; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; Signal Transduction; Silver Staining; Thiazoles | 2002 |
Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Disease Models, Animal; Female; Humans; Male; Membrane Proteins; Mice; Mice, Transgenic; Neurotoxins; Plaque, Amyloid; Presenilin-1; Thiazoles | 2002 |
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.
Topics: Amino Acid Substitution; Animals; Apoptosis; Benzothiazoles; Brain; Brain Chemistry; Cell Count; Disease Models, Animal; Homozygote; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Motor Neurons; Neurodegenerative Diseases; Paraparesis; Phenotype; Phosphorylation; Sarcosine; Solubility; Spinal Cord; tau Proteins; Thiazoles | 2002 |
Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Binding, Competitive; Blood-Brain Barrier; Brain; Contrast Media; Disease Models, Animal; Gadolinium; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Membrane Proteins; Mice; Mice, Transgenic; Molecular Probe Techniques; Neurons; Peptide Fragments; Plaque, Amyloid; Predictive Value of Tests; Presenilin-1; Putrescine; Reproducibility of Results; Thiazoles | 2002 |
In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories.
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Axons; Benzothiazoles; Cerebral Cortex; Dendrites; Dextrans; Disease Models, Animal; Fluorescent Dyes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Neurites; Neuropil; Plaque, Amyloid; Thiazoles | 2003 |
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Benzothiazoles; Cerebral Cortex; Cyclic N-Oxides; Disease Models, Animal; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Infrared Rays; Lasers; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Plaque, Amyloid; Reactive Oxygen Species; Thiazoles | 2003 |
Inflammation occurs early during the Abeta deposition process in TgCRND8 mice.
Topics: Age Factors; Alzheimer Disease; Amygdala; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; CD11b Antigen; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neocortex; Plaque, Amyloid; Thiazoles | 2004 |
Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Blood Vessels; Brain; Cholesterol; Copper; Disease Models, Animal; Drug Synergism; Food, Formulated; Immunohistochemistry; Male; Metabolic Clearance Rate; Neurons; Rabbits; Thiazoles; Up-Regulation | 2004 |
Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Fluorescent Dyes; Heterozygote; Humans; Immunization, Passive; Immunotherapy; Metabolic Clearance Rate; Mice; Mice, Transgenic; Neurites; Neurofibrillary Tangles; Plaque, Amyloid; Thiazoles | 2004 |
Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Intermediate Filament Proteins; Mice; Mice, Transgenic; Thiazoles | 2004 |
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
Topics: 3-Hydroxybutyric Acid; alpha-Synuclein; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Apoptosis; Benzoates; Benzothiazoles; Bile Acids and Salts; Caenorhabditis elegans; Cholagogues and Choleretics; Copper; Disease Models, Animal; Electron Transport Complex I; Gene Deletion; Gene Expression Regulation; Gene Library; Genetic Techniques; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ions; Iron; Mitochondria; Molecular Sequence Data; Mutagenesis; Mutation; Neurons; Oncogene Proteins; Oxygen Consumption; Paraquat; Parkinson Disease; Polyenes; Probucol; Protein Deglycase DJ-1; Pyrazoles; Pyridazines; RNA, Small Interfering; Rotenone; Sequence Homology, Amino Acid; Sodium Azide; Taurochenodeoxycholic Acid; Thiazoles; Time Factors; Transgenes; Ubiquitin-Protein Ligases | 2005 |
In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice.
Topics: Age Factors; Alzheimer Disease; Animals; Benzothiazoles; Brain Mapping; Disease Models, Animal; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Plaque, Amyloid; Staining and Labeling; Thiazoles | 2005 |
Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Benzothiazoles; Disease Models, Animal; Fluoresceins; Gene Expression; Genetic Vectors; Hippocampus; Humans; Immunohistochemistry; Male; Maze Learning; Memory Disorders; Mutation; Organic Chemicals; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiazoles | 2006 |
[Experimental model for determination of an "in vivo" area at risk accounting for the quantity and distribution of collateral flow (author's transl)].
Topics: Animals; Arrhythmias, Cardiac; Autoradiography; Benzothiazoles; Collateral Circulation; Coronary Circulation; Disease Models, Animal; Dogs; Fluorescent Dyes; Microspheres; Myocardial Infarction; Risk; Serum Albumin; Thiazoles | 1982 |
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Apolipoproteins E; Benzothiazoles; Disease Models, Animal; Genetic Predisposition to Disease; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Nerve Degeneration; Neurites; Plaque, Amyloid; Protein Isoforms; Thiazoles; Time Factors | 2000 |
Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.
Topics: Alzheimer Disease; Animals; Benzothiazoles; Disease Models, Animal; Disease Progression; Feedback; Fluorescent Dyes; Image Processing, Computer-Assisted; Male; Mice; Mice, Transgenic; Microscopy; Plaque, Amyloid; Thiazoles | 2001 |
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.
Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine | 2001 |
Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cell Count; Data Interpretation, Statistical; Disease Models, Animal; Hippocampus; Image Processing, Computer-Assisted; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Plaque, Amyloid; Reproducibility of Results; Statistical Distributions; Thiazoles | 2001 |
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.
Topics: Animals; Benzothiazoles; Brain; Cerebral Cortex; Coloring Agents; Congo Red; Disease Models, Animal; Female; Gene Expression Regulation; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutation, Missense; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Protein Structure, Secondary; tau Proteins; Thiazoles; Transfection; Ubiquitin | 2001 |
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Congo Red; Disease Models, Animal; Gene Expression Regulation, Developmental; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Insertional; Mutation; Neurites; Neurons; Peptide Fragments; Plaque, Amyloid; Presynaptic Terminals; Promoter Regions, Genetic; Thiazoles | 2001 |
Amyloid-beta deposits in the cerebral cortex of the aged common marmoset (Callithrix jacchus): incidence and chemical composition.
Topics: Aging; alpha 1-Antichymotrypsin; Amyloid beta-Peptides; Animals; Apolipoproteins E; Benzothiazoles; Brain Diseases; Callithrix; Cerebral Cortex; Cholinesterases; Disease Models, Animal; Female; Incidence; Male; Neurites; Peptide Fragments; Plaque, Amyloid; Survival Analysis; Thiazoles | 2002 |
[Effect of TFX (Polfa) on the course of experimental bacterial infections in mice treated with ciprofloxacin, amikacin and cefoperazone].
Topics: Amikacin; Animals; Cefoperazone; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Escherichia coli Infections; Female; Male; Mice; Mice, Inbred BALB C; Staphylococcal Infections; Staphylococcus aureus; Thymus Extracts | 1992 |