Page last updated: 2024-08-22

thioflavin t and Disease Models, Animal

thioflavin t has been researched along with Disease Models, Animal in 74 studies

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.35)18.7374
1990's1 (1.35)18.2507
2000's33 (44.59)29.6817
2010's32 (43.24)24.3611
2020's7 (9.46)2.80

Authors

AuthorsStudies
Haratake, M; Hori, M; Mori, H; Nakayama, M; Ono, M; Tomiyama, T1
Hur, MG; Kim, SW; Min, JJ; Park, JH; Park, SH; Park, YD; Yang, SD; Yoo, YJ; Yoon, YJ1
Aguirre, C; Baba, K; Choong, CJ; Doi, J; Goto, Y; Hideshima, M; Ikenaka, K; Kakuda, K; Kimura, Y; Mochizuki, H; Nabekura, K; Nagai, Y; Nagano, S; Nakajima, K; Takeuchi, T; Yamaguchi, K1
Hagimori, M; Haratake, Y; Minaki, K; Mukai, T; Munekane, M; Sano, K; Tsuchiya, M; Yamasaki, T1
Nair, AV; Ran, C; Ran, K; Yang, J; Zhu, B1
Girigoswami, A; Girigoswami, K; Metkar, SK; Vijayashree, R1
Genov, M; Hummel, T; Kasture, A; Krenn, L; Moloney, M; Pretsch, A; Pretsch, D; Rollinger, JM; Schmid, A; Wöhrer, T1
Kim, Y; Lee, H; Park, S; Shin, J1
Alijanvand, SH; Burdukiewicz, M; Christensen, LFB; Dueholm, MS; Herbst, FA; Kjeldal, H; Otzen, DE1
Ackermann, M; Denver, P; Kelly, P; Konerding, MA; Mitchell, CA; Satchell, SC1
Eriksen, JL; Georgiou, P; Gould, TD; Jarvela, TS; Lindberg, I; Womack, T1
Gao, Y; He, X; Liu, Q; Xu, F; Xu, L; Zheng, N1
Johnstone, DM; Marotte, L; Purushothuman, S; Stone, J; Stowe, S1
Georgopoulos, S; Klinakis, A; Paouri, E; Sesele, K; Thanopoulou, K; Tsefou, E1
Duncker, DJ; Gorsse-Bakker, C; Krabbendam-Peters, I; Sneep, S; Uitterdijk, A; van Beusekom, HM; van der Giessen, WJ; van Duin, RW1
Bongarzone, ER; Cantuti-Castelvetri, L; Celej, MS; Claycomb, KI; Crocker, SJ; Gallea, JI; Givogri, MI; Li, G; Lopez-Rosas, A; Marshall, MS; Santos, MB; Smith, BR; van Breemen, R1
Fitzgerald, S; Lauer, SL; Levy, E; Lopez-Guzman, M; Nixon, RA; Schoen, C; Wilson, DA; Xu, W1
Bartic, C; Benilova, I; Castillo Cano, V; De Strooper, B; Gallardo, R; Ramakers, M; Rousseau, F; Schymkowitz, J; Snellinx, A; Ungureanu, AA1
Hatou, S; Inagaki, E; Ogawa, Y; Shimmura, S; Tsubota, K; Yamazoe, K; Yasuda, M; Yoshida, S1
Moir, RD; Moore, A; Ran, C; Ross, AW; Sun, H; Tanzi, RE; Tian, X; Tian, Y; Zhang, C; Zhang, X1
Bodi, V; Bonanad, C; Chorro, FJ; de Dios, E; Forteza, MJ; Hervas, A; Miñana, G; Nuñez, J; Perez-Sole, N; Ruiz-Sauri, A1
Lahiri, DK; Paule, MG; Ray, B; Raymick, J; Sarkar, S; Schmued, L1
Choi, B; Crouzet, C; Lo, P; Vasilevko, V1
Alberi, L; Alina Raio, N; Brai, E1
Ashe, KH; Borchelt, DR; Forster, CL; Hemmy, LS; Huang, ES; Kuskowski, MA; Liu, P; McNellis, BM; Rao, ER; Reichl, JH; Vassar, R; Zahs, KR1
Etienne, MA; Gordon, M; Hammer, RP; Li, Q; Morgan, D1
Csernansky, JG; Deal, C; Dong, H; Mace, AG; Martin, MV; Yoo, HS; Yuede, CM1
Beach, TG; Castaño, EM; Daugs, ID; Davis, J; Esh, CL; Kalback, WM; Kokjohn, TA; Lue, LF; Luehrs, DC; Patton, RL; Roher, AE; Van Nostrand, WE; Van Vickle, GD; Walker, DG1
Levine, H; Walker, LC1
Kellaway, LA; Kotwal, GJ; Kulkarni, AP; Pillay, NS1
Kovacs, B; Lumayag, S; Mufson, EJ; Perez, SE; Xu, S1
Arai, H; Fujiwara, H; Gamoh, S; Hashimoto, M; Katakura, M; Miyazawa, T; Shahdat, HM; Shido, O; Shimada, T; Tanabe, Y; Yamashita, S1
Bero, AW; Csernansky, JG; Dong, H; Holtzman, DM; Kling, MJ; Timson, BF; Yuede, CM; Zimmerman, SD1
Lundmark, K; Westermark, GT; Westermark, P1
Cook, J; DeArmond, SJ; Lemus, A; Mastrianni, JA; Rassbach, B; Yang, W1
Bowles, N; Gaspar, RC; Hepler, RW; Joyce, JG; Shughrue, PJ; Villarreal, SA1
Anan, M; Hara, H; Kataoka, S; Mutoh, T; Tabira, T; Ueda, A1
Huang, W; Lei, H; Wang, X; Xu, W; Zhan, Y; Zhang, S1
Borbon, IA; Erickson, RP1
Arendt, T; Brückner, MK; Hoyer, S; Osmanovic-Barilar, J; Riederer, P; Salkovic-Petrisic, M1
Ansciaux, E; Burtea, C; Larbanoix, L; Laurent, S; Mahieu, I; Muller, RN; Vander Elst, L1
Georgopoulos, S; Katsouri, L1
Chamberlain, R; Curran, GL; Garwood, M; Hultman, KL; Jack, CR; Marjańska, M; Poduslo, JF; Preboske, GM; Wengenack, TM1
Cardoso, I; Costa, R; Crowther, DC; Speretta, E1
Borkowski, AH; Landreth, GE; Levy, E; Nixon, RA; Wesson, DW; Wilson, DA1
Bartnik, D; Brener, O; Funke, SA; Liu, H; Nagel-Steger, L; Sehl, T; Wiesehan, K; Willbold, D1
Ke, YN; Li, AL; Li, JH; Li, XL; Shi, ZX; Wang, Y; Yang, P1
Han, H; Kim, HY; Kim, Y; Lee, YS; Roh, EJ; Seo, JH; Shin, KJ1
Beker, S; Kellner, V; Kerti, L; Stern, EA1
Borchelt, DR; Coonfield, M; Copeland, NG; Fromholt, D; Gonzales, V; Jenkins, NA; Wang, J; Xu, G1
Aronow, BJ; Bales, KR; DeMattos, RB; Harmony, JA; Holtzman, DM; O'dell, MA; Parsadanian, M; Paul, SM; Taylor, JW1
Bacskai, BJ; Games, D; Hyman, BT; Kajdasz, ST; McLellan, ME; Schenk, D; Seubert, P1
Capsoni, S; Cattaneo, A; Giannotta, S1
Ashe, KH; Cruz, L; Duff, K; Hyman, BT; Irizarry, MC; Le, R; Sanders, J; Stanley, HE; Urbanc, B1
Allen, B; Atzori, C; Craxton, M; Crowther, RA; Emson, PC; Ghetti, B; Goedert, M; Holzer, M; Ingram, E; Jakes, R; Migheli, A; Smith, MJ; Spillantini, MG; Takao, M; Virdee, K; Yoshida, H1
Borowski, BJ; Curran, GL; Jack, CR; Macura, SI; Poduslo, JF; Sigurdsson, EM; Wengenack, TM; Wisniewski, T1
Bacskai, BJ; D'Amore, JD; Hyman, BT; Kajdasz, ST; McLellan, ME; Stern, EA1
Bacskai, BJ; Hyman, BT; Kajdasz, ST; McLellan, ME1
Dudal, S; Gervais, F; Krzywkowski, P; Lacombe, D; Morissette, C; Paquette, J; Tremblay, P1
Larry Sparks, D1
Barbour, R; Bard, F; Bussière, T; Buttini, M; Games, D; Grajeda, H; Guido, T; Khan, K; Schenk, D; Seubert, P1
Bales, KR; Costa, DA; Nilsson, LN; Paul, SM; Potter, H1
Alfonso, A; Burnam, L; Hoener, M; Liu, L; Perier, C; Przedborski, S; Rodrigues, CM; Saha, S; Sluder, A; Steer, C; Ved, R; Westlund, B; Wolozin, B1
Adriany, G; Borowski, BJ; Curran, GL; Garwood, M; Holasek, SS; Jack, CR; Lin, J; Poduslo, JF; Preboske, GM; Reyes, DA; Wengenack, TM1
Gong, Y; Hughes, JA; King, MA; Klein, RL; Meyer, EM; Meyers, CA1
Glogar, D; Mayr, H; Mohl, W; Sochor, H; Weber, H1
Bales, KR; Fagan, AM; Holtzman, DM; Mackey, B; McKeel, D; Olney, J; Parsadanian, M; Paul, SM; Sartorius, LJ; Tenkova, T; Wozniak, D1
Bacskai, BJ; Christie, RH; Hyman, BT; Kajdasz, ST; Webb, WW; Williams, RM; Zipfel, WR1
Duff, K; La Francois, J; Matsuoka, Y; Picciano, M1
Bales, KR; Cummins, DJ; DeLong, CA; Esterman, MA; Fishman, CE; Hanson, JC; Jordan, WH; Paul, SM; White, SL1
Akagi, T; Hashikawa, T; Kikuchi, N; Matsuda, K; Murayama, M; Murayama, O; Nakao, S; Park, JM; Sato, S; Sun, X; Takashima, A; Tanemura, K; Yamaguchi, H; Yoshiike, Y1
Mallory, M; Mante, M; Masliaha, E; Rockenstein, E; Sisk, A1
Geula, C; Nagykery, N; Wu, CK1
Ciebieda, I; Denys, A; Ferszt, T; Korczak, E1

Other Studies

74 other study(ies) available for thioflavin t and Disease Models, Animal

ArticleYear
Structure-activity relationship of chalcones and related derivatives as ligands for detecting of beta-amyloid plaques in the brain.
    Bioorganic & medicinal chemistry, 2007, Oct-01, Volume: 15, Issue:19

    Topics: Alzheimer Disease; Animals; Binding, Competitive; Brain; Chalcones; Disease Models, Animal; Ligands; Mice; Plaque, Amyloid; Structure-Activity Relationship

2007
Fluorescent 2-styrylpyridazin-3(2H)-one derivatives as probes targeting amyloid-beta plaques in Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Fluorescence; Fluorescent Dyes; Humans; Mice; Mice, Transgenic; Plaque, Amyloid; Pyridazines; Sensitivity and Specificity; Spectrometry, Fluorescence; Staining and Labeling

2012
Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson's disease.
    Scientific reports, 2022, 01-10, Volume: 12, Issue:1

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Antiparkinson Agents; Benzothiazoles; Biological Assay; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Drug Repositioning; HeLa Cells; High-Throughput Screening Assays; Humans; Mice, Inbred C57BL; Neurons; Parkinson Disease; Protein Aggregates; Protein Aggregation, Pathological; Spectrometry, Fluorescence; Tannins

2022
Development of a radioiodinated thioflavin-T-Congo-red hybrid probe for diagnosis of systemic amyloidosis.
    Bioorganic & medicinal chemistry, 2022, 02-15, Volume: 56

    Topics: Amyloidosis; Animals; Autoradiography; Benzothiazoles; Congo Red; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Development; Female; Iodine Radioisotopes; Mice; Mice, Inbred ICR; Molecular Structure; Radiopharmaceuticals; Structure-Activity Relationship

2022
CRANAD-28: A Robust Fluorescent Compound for Visualization of Amyloid Beta Plaques.
    Molecules (Basel, Switzerland), 2020, Feb-16, Volume: 25, Issue:4

    Topics: Alzheimer Disease; Animals; Benzothiazoles; Boron Compounds; Brain; Curcumin; Disease Models, Animal; Female; Fluorescent Dyes; Humans; Mice; Mice, Transgenic; Microglia; Microscopy, Confocal; Microtomy; Plaque, Amyloid; Staining and Labeling

2020
Attenuation of subcutaneous insulin induced amyloid mass in vivo using Lumbrokinase and Serratiopeptidase.
    International journal of biological macromolecules, 2020, Nov-15, Volume: 163

    Topics: Animals; Benzothiazoles; Congo Red; Disease Models, Animal; Endopeptidases; Injection Site Reaction; Injections, Subcutaneous; Insulin; Male; Microscopy, Fluorescence; Microscopy, Polarization; Peptide Hydrolases; Plaque, Amyloid; Protein Aggregation, Pathological; Rats; Rats, Wistar; Subcutaneous Tissue

2020
Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
    Scientific reports, 2020, 07-16, Volume: 10, Issue:1

    Topics: Aging; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Benzothiazoles; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Clioquinol; Disease Models, Animal; Emodin; Gene Knockdown Techniques; Homeostasis; Metallothionein; Metals; Neuroprotective Agents; Parkinson Disease; Quercetin; Signal Transduction

2020
Thioflavin-positive tau aggregates complicating quantification of amyloid plaques in the brain of 5XFAD transgenic mouse model.
    Scientific reports, 2021, 01-15, Volume: 11, Issue:1

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Female; Male; Mice; Mice, Transgenic; Phosphorylation; Piperazines; Protein Aggregates; Protein Conformation, beta-Strand; tau Proteins

2021
Identification of amyloidogenic proteins in the microbiomes of a rat Parkinson's disease model and wild-type rats.
    Protein science : a publication of the Protein Society, 2021, Volume: 30, Issue:9

    Topics: alpha-Synuclein; Amino Acid Sequence; Amyloid; Amyloidogenic Proteins; Animals; Bacterial Proteins; Benzothiazoles; Biofilms; Disease Models, Animal; Endopeptidase K; Feces; Female; Formates; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; Microbial Consortia; Parkinson Disease; Protein Aggregates; Rats; Rats, Transgenic; Urea

2021
Microvascular ultrastructural changes precede cognitive impairment in the murine APPswe/PS1dE9 model of Alzheimer's disease.
    Angiogenesis, 2017, Volume: 20, Issue:4

    Topics: Alzheimer Disease; Animals; Benzothiazoles; Capillaries; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Exploratory Behavior; Intussusception; Kidney Glomerulus; Liver; Male; Memory, Short-Term; Mice, Transgenic; Microvessels; Plaque, Amyloid; Spleen; Thiazoles

2017
7B2 chaperone knockout in APP model mice results in reduced plaque burden.
    Scientific reports, 2018, 06-28, Volume: 8, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Clusterin; Disease Models, Animal; Female; Genotype; Heterozygote; Humans; Memory; Mice, Inbred C57BL; Mice, Knockout; Neuroendocrine Secretory Protein 7B2; Plaque, Amyloid; Solubility; Transgenes

2018
Imaging and Spectral Characteristics of Amyloid Plaque Autofluorescence in Brain Slices from the APP/PS1 Mouse Model of Alzheimer's Disease.
    Neuroscience bulletin, 2019, Volume: 35, Issue:6

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Disease Models, Animal; Fluorescence; Fluorescent Antibody Technique; Mice; Mice, Transgenic; Optical Imaging; Plaque, Amyloid; Presenilin-1; Silver Staining; Staining and Labeling; Ultraviolet Rays

2019
The response of cerebral cortex to haemorrhagic damage: experimental evidence from a penetrating injury model.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Astrocytes; Benzothiazoles; Brain; Brain Injuries; Cell Death; Cerebral Cortex; Congo Red; Disease Models, Animal; Female; Ferrocyanides; Heme; Hemorrhage; Hippocampus; Humans; Immunohistochemistry; Male; Neocortex; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins; Temporal Lobe; Thiazoles; Wounds, Penetrating

2013
Conditional inactivation of nicastrin restricts amyloid deposition in an Alzheimer's disease mouse model.
    Aging cell, 2013, Volume: 12, Issue:6

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Gliosis; Humans; Integrases; Membrane Glycoproteins; Mice; Mice, Transgenic; Nerve Degeneration; Neurons; Phenotype; Presenilin-1; Thiazoles

2013
Serial measurement of hFABP and high-sensitivity troponin I post-PCI in STEMI: how fast and accurate can myocardial infarct size and no-reflow be predicted?
    American journal of physiology. Heart and circulatory physiology, 2013, Oct-01, Volume: 305, Issue:7

    Topics: Animals; Benzothiazoles; Biomarkers; Coronary Circulation; Disease Models, Animal; Fatty Acid-Binding Proteins; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Necrosis; No-Reflow Phenomenon; Predictive Value of Tests; Risk Factors; Staining and Labeling; Swine; Tetrazolium Salts; Thiazoles; Time Factors; Troponin I; Up-Regulation

2013
Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.
    The Journal of pathology, 2014, Volume: 232, Issue:5

    Topics: alpha-Synuclein; Animals; Benzothiazoles; Brain; Case-Control Studies; Cognition; Disease Models, Animal; Fluorescent Dyes; Humans; Leukodystrophy, Globoid Cell; Lewy Bodies; Mice; Motor Activity; Mutation; Neurons; Psychosine; Thiazoles

2014
Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Alzheimer Disease; Animals; Behavior, Animal; Benzothiazoles; Disease Models, Animal; Entorhinal Cortex; Female; Habituation, Psychophysiologic; Hippocampus; Male; Memory; Mice, Transgenic; Odorants; Olfactory Bulb; Olfactory Pathways; Piriform Cortex; Thiazoles

2014
The Alzheimer disease protective mutation A2T modulates kinetic and thermodynamic properties of amyloid-β (Aβ) aggregation.
    The Journal of biological chemistry, 2014, Nov-07, Volume: 289, Issue:45

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzothiazoles; Brain; Cell Culture Techniques; Cell Line; Cricetinae; Disease Models, Animal; Humans; Kinetics; Mice; Mice, Inbred C57BL; Mutagenesis; Mutation; Neurons; Peptide Fragments; Solubility; Thermodynamics; Thiazoles

2014
Development of a Transgenic Mouse with R124H Human TGFBI Mutation Associated with Granular Corneal Dystrophy Type 2.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Alleles; Animals; Base Sequence; Benzothiazoles; Corneal Dystrophies, Hereditary; Disease Models, Animal; DNA Primers; DNA, Complementary; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Microscopy, Electron; Microtubule-Associated Proteins; Mutation; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Transforming Growth Factor beta1

2015
Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Aug-04, Volume: 112, Issue:31

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Carbon-13 Magnetic Resonance Spectroscopy; Disease Models, Animal; Drug Monitoring; Fluorescent Dyes; Humans; Mice, Transgenic; Molecular Imaging; Photons; Presenilin-1; Proton Magnetic Resonance Spectroscopy; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared; Thiazoles; Tissue Extracts; Titrimetry

2015
Intracoronary Infusion of Thioflavin-S to Study Microvascular Obstruction in a Model of Myocardial Infarction.
    Revista espanola de cardiologia (English ed.), 2015, Volume: 68, Issue:11

    Topics: Animals; Benzothiazoles; Coronary Angiography; Coronary Circulation; Coronary Occlusion; Coronary Vessels; Disease Models, Animal; Fluorescent Dyes; Infusions, Intra-Arterial; Microcirculation; Microvessels; Myocardial Infarction; Myocardial Reperfusion Injury; Photography; Sus scrofa; Swine; Thiazoles; Ultraviolet Rays

2015
Oral Administration of Thioflavin T Prevents Beta Amyloid Plaque Formation in Double Transgenic AD Mice.
    Current Alzheimer research, 2015, Volume: 12, Issue:9

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Benzothiazoles; Brain; Disease Models, Animal; Female; Male; Mice, Transgenic; Microglia; Neuroprotective Agents; Peptide Fragments; Plaque, Amyloid; Thiazoles

2015
Visualization of microbleeds with optical histology in mouse model of cerebral amyloid angiopathy.
    Microvascular research, 2016, Volume: 105

    Topics: Animals; Benzothiazoles; Carbocyanines; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Fluorescent Dyes; Genetic Predisposition to Disease; Imaging, Three-Dimensional; Mice, Transgenic; Microcirculation; Microscopy, Confocal; Microvessels; Optical Imaging; Plaque, Amyloid; Staining and Labeling; Thiazoles

2016
Notch1 hallmarks fibrillary depositions in sporadic Alzheimer's disease.
    Acta neuropathologica communications, 2016, 07-01, Volume: 4, Issue:1

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Animals; Benzothiazoles; Biomarkers; Blotting, Western; Cell Line, Tumor; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Humans; Immunohistochemistry; Liver; Male; Mice; Middle Aged; Plaque, Amyloid; Receptor, Notch1; tau Proteins; Thiazoles

2016
Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 56, Issue:2

    Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Humans; Male; Mice, Transgenic; Plaque, Amyloid; Species Specificity; Thiazoles

2017
Contrasting in vivo effects of two peptide-based amyloid-beta protein aggregation inhibitors in a transgenic mouse model of amyloid deposition.
    Cell transplantation, 2008, Volume: 17, Issue:4

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Microglia; Molecular Structure; Peptides; Plaque, Amyloid; Thiazoles

2008
Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice.
    Neuroscience, 2008, Jul-31, Volume: 155, Issue:1

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Benzothiazoles; Corticosterone; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Mutation; Plaque, Amyloid; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; Stress, Psychological; Thiazoles

2008
Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy.
    The American journal of pathology, 2008, Volume: 173, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Benzothiazoles; Cerebral Amyloid Angiopathy; Dimerization; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Plaque, Amyloid; Protein Conformation; Thiazoles

2008
Molecular polymorphism of Abeta in Alzheimer's disease.
    Neurobiology of aging, 2010, Volume: 31, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Benzothiazoles; Binding Sites; Binding, Competitive; Coloring Agents; Congo Red; Diagnostic Imaging; Disease Models, Animal; Humans; Ligands; Molecular Probes; Pathology, Molecular; Plaque, Amyloid; Predictive Value of Tests; Protein Isoforms; Thiazoles

2010
Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test.
    Biogerontology, 2008, Volume: 9, Issue:6

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Association Learning; Behavior, Animal; Benzothiazoles; Complement System Proteins; Conditioning, Psychological; Disease Models, Animal; Genotype; Injections; Maze Learning; Mice; Mice, Transgenic; Reversal Learning; Space Perception; Thiazoles; Viral Proteins

2008
Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Differentiation; Benzothiazoles; Choline O-Acetyltransferase; Disease Models, Animal; Electroretinography; Female; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Presenilin-1; Retina; Retinal Diseases; Syntaxin 1; Thiazoles

2009
Docosahexaenoic acid disrupts in vitro amyloid beta(1-40) fibrillation and concomitantly inhibits amyloid levels in cerebral cortex of Alzheimer's disease model rats.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies; Benzothiazoles; Cerebral Cortex; Cholesterol; Disease Models, Animal; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Hippocampus; Microscopy, Electron, Transmission; Neurofibrillary Tangles; Peptide Fragments; Rats; Rats, Wistar; Thiazoles

2008
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease.
    Neurobiology of disease, 2009, Volume: 35, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Hippocampus; Humans; Memory; Memory Disorders; Mice; Mice, Transgenic; Organ Size; Peptide Fragments; Physical Conditioning, Animal; Protease Nexins; Random Allocation; Receptors, Cell Surface; Recognition, Psychology; Thiazoles; Time Factors

2009
Fibrils from designed non-amyloid-related synthetic peptides induce AA-amyloidosis during inflammation in an animal model.
    PloS one, 2009, Jun-30, Volume: 4, Issue:6

    Topics: Amyloid; Amyloidosis; Animals; Benzothiazoles; Coloring Agents; Congo Red; Disease Models, Animal; Female; Humans; Inflammation; Mice; Peptides; Spleen; Thiazoles; Time Factors

2009
A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Aug-12, Volume: 29, Issue:32

    Topics: Animals; Ataxia; Benzothiazoles; Blotting, Western; Brain; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Gerstmann-Straussler-Scheinker Disease; Humans; Kaplan-Meier Estimate; Mice; Mice, Transgenic; Mutation, Missense; Phenotype; Prion Proteins; Prions; PrPC Proteins; PrPSc Proteins; Thiazoles; Time Factors

2009
Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model.
    Experimental neurology, 2010, Volume: 223, Issue:2

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Benzothiazoles; Biotin; Disease Models, Animal; Humans; Immunohistochemistry; Islet Amyloid Polypeptide; Ligands; Male; Mice; Mice, Transgenic; Microscopy, Atomic Force; Molecular Weight; Peptide Fragments; Plaque, Amyloid; Thiazoles

2010
The therapeutic effects of the herbal medicine, Juzen-taiho-to, on amyloid-beta burden in a mouse model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20, Issue:2

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Antipsychotic Agents; Benzothiazoles; Bone Marrow Cells; Calcium-Binding Proteins; Cell Culture Techniques; Cytokines; Disease Models, Animal; DNA-Binding Proteins; Drugs, Chinese Herbal; Flow Cytometry; Gene Expression Regulation; Humans; Ki-67 Antigen; Macrophages; Mice; Mice, Transgenic; Microfilament Proteins; Mutation; Thiazoles

2010
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
    Journal of neuroscience research, 2010, Nov-01, Volume: 88, Issue:14

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA1 Region, Hippocampal; Creatine; Disease Models, Animal; Down-Regulation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Nerve Degeneration; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Thiazoles

2010
Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's.
    Journal of applied genetics, 2011, Volume: 52, Issue:2

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Peptide Fragments; Plaque, Amyloid; Proteins; Regression Analysis; Thiazoles

2011
Cerebral amyloid angiopathy in streptozotocin rat model of sporadic Alzheimer's disease: a long-term follow up study.
    Journal of neural transmission (Vienna, Austria : 1996), 2011, Volume: 118, Issue:5

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibiotics, Antineoplastic; Benzothiazoles; Cerebral Amyloid Angiopathy; Disease Models, Animal; Disease Progression; Longitudinal Studies; Male; Peptide Fragments; Rats; Rats, Wistar; Staining and Labeling; Streptozocin; Thiazoles

2011
Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library.
    Peptides, 2011, Volume: 32, Issue:6

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Benzothiazoles; Biotinylation; Blood-Brain Barrier; Contrast Media; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Kinetics; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Models, Molecular; Molecular Sequence Data; Molecular Targeted Therapy; Mutagenesis, Site-Directed; Peptide Fragments; Peptide Library; Peptides, Cyclic; Plaque, Amyloid; Protein Binding; Sequence Analysis, DNA; Thiazoles

2011
Lack of LDL receptor enhances amyloid deposition and decreases glial response in an Alzheimer's disease mouse model.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Apolipoproteins E; Astrocytes; Benzothiazoles; Disease Models, Animal; Hippocampus; Humans; Mice; Mice, Transgenic; Microglia; Neuroglia; Plaque, Amyloid; Protein Processing, Post-Translational; Receptors, LDL; Thiazoles

2011
Targeting vascular amyloid in arterioles of Alzheimer disease transgenic mice with amyloid β protein antibody-coated nanoparticles.
    Journal of neuropathology and experimental neurology, 2011, Volume: 70, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Arterioles; Benzothiazoles; Disease Models, Animal; Ferric Compounds; Humans; Immunoglobulin G; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Nanoparticles; Peptide Fragments; Plaque, Amyloid; Platelet Endothelial Cell Adhesion Molecule-1; Thiazoles

2011
Testing the therapeutic potential of doxycycline in a Drosophila melanogaster model of Alzheimer disease.
    The Journal of biological chemistry, 2011, Dec-02, Volume: 286, Issue:48

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Anti-Bacterial Agents; Benzothiazoles; Caspase 3; Cell Line, Tumor; Disease Models, Animal; Doxycycline; Drosophila melanogaster; Fluorescent Dyes; Humans; Longevity; Thiazoles

2011
Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-02, Volume: 31, Issue:44

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Behavioral Symptoms; Benzoates; Benzothiazoles; Benzylamines; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Enzyme-Linked Immunosorbent Assay; Fourier Analysis; Habituation, Psychophysiologic; Humans; Mice; Mice, Transgenic; Odorants; Olfactory Pathways; Sensation Disorders; Smell; Thiazoles

2011
Identification and characterization of an aβ oligomer precipitating peptide that may be useful to explore gene therapeutic approaches to Alzheimer disease.
    Rejuvenation research, 2012, Volume: 15, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Cell Line, Tumor; Centrifugation, Density Gradient; Disease Models, Animal; Genetic Therapy; Humans; Mice; Nephelometry and Turbidimetry; Neurons; Peptides; Sequence Analysis, DNA; Thiazoles

2012
The preventive effect of garlicin on a porcine model of myocardial infarction reperfusion no-reflow.
    Chinese journal of integrative medicine, 2014, Volume: 20, Issue:6

    Topics: Allyl Compounds; Animals; Benzothiazoles; Cardiotonic Agents; Contrast Media; Disease Models, Animal; Disulfides; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; No-Reflow Phenomenon; Swine; Swine, Miniature; Thiazoles; Ultrasonography

2014
Small molecules that protect against β-amyloid-induced cytotoxicity by inhibiting aggregation of β-amyloid.
    Bioorganic & medicinal chemistry, 2012, Aug-15, Volume: 20, Issue:16

    Topics: Amyloid beta-Peptides; Animals; Benzene Derivatives; Benzothiazoles; Cells, Cultured; Coumaric Acids; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred ICR; Molecular Structure; Molecular Weight; Peptide Fragments; Resveratrol; Stilbenes; Thiazoles

2012
Interaction between amyloid-β pathology and cortical functional columnar organization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Aug-15, Volume: 32, Issue:33

    Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Benzothiazoles; Brain Mapping; Disease Models, Animal; Electron Transport Complex IV; Humans; Mice; Mice, Transgenic; Models, Neurological; Mutation; Neural Pathways; Plaque, Amyloid; Presenilin-1; Somatosensory Cortex; Thiazoles

2012
Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.
    Neurobiology of disease, 2002, Volume: 10, Issue:2

    Topics: Amino Acid Substitution; Animals; Benzothiazoles; Binding Sites; Copper; Disease Models, Animal; Female; Histidine; Humans; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Motor Neuron Disease; Motor Neurons; Mutation, Missense; Nerve Tissue Proteins; Neurofibrils; Protein Folding; Spinal Cord; Structure-Activity Relationship; Superoxide Dismutase; Superoxides; Thiazoles

2002
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Aug-06, Volume: 99, Issue:16

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Clusterin; Disease Models, Animal; Glycoproteins; Mice; Mice, Knockout; Molecular Chaperones; Neurites; Peptide Fragments; Plaque, Amyloid; Thiazoles

2002
Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Sep-15, Volume: 22, Issue:18

    Topics: Administration, Topical; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antibodies; Benzothiazoles; Brain; Disease Models, Animal; Fluorescent Dyes; Humans; Immunoglobulin Fab Fragments; Immunoglobulin Fc Fragments; Immunotherapy; Mice; Mice, Transgenic; Microscopy, Fluorescence; Mutation; Phagocytosis; Plaque, Amyloid; Thiazoles

2002
Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies.
    Molecular and cellular neurosciences, 2002, Volume: 21, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoantibodies; Benzothiazoles; Brain; Cerebellum; Disease Models, Animal; Locus Coeruleus; Mice; Mice, Transgenic; Neostriatum; Nerve Growth Factor; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; Signal Transduction; Silver Staining; Thiazoles

2002
Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Oct-29, Volume: 99, Issue:22

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Disease Models, Animal; Female; Humans; Male; Membrane Proteins; Mice; Mice, Transgenic; Neurotoxins; Plaque, Amyloid; Presenilin-1; Thiazoles

2002
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Nov-01, Volume: 22, Issue:21

    Topics: Amino Acid Substitution; Animals; Apoptosis; Benzothiazoles; Brain; Brain Chemistry; Cell Count; Disease Models, Animal; Homozygote; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Motor Neurons; Neurodegenerative Diseases; Paraparesis; Phenotype; Phosphorylation; Sarcosine; Solubility; Spinal Cord; tau Proteins; Thiazoles

2002
Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.
    Neurobiology of disease, 2002, Volume: 11, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Binding, Competitive; Blood-Brain Barrier; Brain; Contrast Media; Disease Models, Animal; Gadolinium; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Membrane Proteins; Mice; Mice, Transgenic; Molecular Probe Techniques; Neurons; Peptide Fragments; Plaque, Amyloid; Predictive Value of Tests; Presenilin-1; Putrescine; Reproducibility of Results; Thiazoles

2002
In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Axons; Benzothiazoles; Cerebral Cortex; Dendrites; Dextrans; Disease Models, Animal; Fluorescent Dyes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Neurites; Neuropil; Plaque, Amyloid; Thiazoles

2003
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Mar-15, Volume: 23, Issue:6

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antioxidants; Benzothiazoles; Cerebral Cortex; Cyclic N-Oxides; Disease Models, Animal; Fluorescent Dyes; Free Radical Scavengers; Free Radicals; Infrared Rays; Lasers; Mice; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Nitrogen Oxides; Oxidation-Reduction; Oxidative Stress; Plaque, Amyloid; Reactive Oxygen Species; Thiazoles

2003
Inflammation occurs early during the Abeta deposition process in TgCRND8 mice.
    Neurobiology of aging, 2004, Volume: 25, Issue:7

    Topics: Age Factors; Alzheimer Disease; Amygdala; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; CD11b Antigen; Disease Models, Animal; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Neocortex; Plaque, Amyloid; Thiazoles

2004
Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain.
    Journal of molecular neuroscience : MN, 2004, Volume: 24, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Blood Vessels; Brain; Cholesterol; Copper; Disease Models, Animal; Drug Synergism; Food, Formulated; Immunohistochemistry; Male; Metabolic Clearance Rate; Neurons; Rabbits; Thiazoles; Up-Regulation

2004
Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance.
    The American journal of pathology, 2004, Volume: 165, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Fluorescent Dyes; Heterozygote; Humans; Immunization, Passive; Immunotherapy; Metabolic Clearance Rate; Mice; Mice, Transgenic; Neurites; Neurofibrillary Tangles; Plaque, Amyloid; Thiazoles

2004
Apolipoprotein is required for the formation of filamentous amyloid, but not for amorphous Abeta deposition, in an AbetaPP/PS double transgenic mouse model of Alzheimer's disease.
    Journal of Alzheimer's disease : JAD, 2004, Volume: 6, Issue:5

    Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Apolipoproteins E; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Intermediate Filament Proteins; Mice; Mice, Transgenic; Thiazoles

2004
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: 3-Hydroxybutyric Acid; alpha-Synuclein; Amino Acid Sequence; Animals; Animals, Genetically Modified; Antioxidants; Apoptosis; Benzoates; Benzothiazoles; Bile Acids and Salts; Caenorhabditis elegans; Cholagogues and Choleretics; Copper; Disease Models, Animal; Electron Transport Complex I; Gene Deletion; Gene Expression Regulation; Gene Library; Genetic Techniques; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Ions; Iron; Mitochondria; Molecular Sequence Data; Mutagenesis; Mutation; Neurons; Oncogene Proteins; Oxygen Consumption; Paraquat; Parkinson Disease; Polyenes; Probucol; Protein Deglycase DJ-1; Pyrazoles; Pyridazines; RNA, Small Interfering; Rotenone; Sequence Homology, Amino Acid; Sodium Azide; Taurochenodeoxycholic Acid; Thiazoles; Time Factors; Transgenes; Ubiquitin-Protein Ligases

2005
In vivo magnetic resonance microimaging of individual amyloid plaques in Alzheimer's transgenic mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, Oct-26, Volume: 25, Issue:43

    Topics: Age Factors; Alzheimer Disease; Animals; Benzothiazoles; Brain Mapping; Disease Models, Animal; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Plaque, Amyloid; Staining and Labeling; Thiazoles

2005
Memory-related deficits following selective hippocampal expression of Swedish mutation amyloid precursor protein in the rat.
    Experimental neurology, 2006, Volume: 200, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Benzothiazoles; Disease Models, Animal; Fluoresceins; Gene Expression; Genetic Vectors; Hippocampus; Humans; Immunohistochemistry; Male; Maze Learning; Memory Disorders; Mutation; Organic Chemicals; Peptide Fragments; Rats; Rats, Sprague-Dawley; Thiazoles

2006
[Experimental model for determination of an "in vivo" area at risk accounting for the quantity and distribution of collateral flow (author's transl)].
    Acta medica Austriaca, 1982, Volume: 9, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Autoradiography; Benzothiazoles; Collateral Circulation; Coronary Circulation; Disease Models, Animal; Dogs; Fluorescent Dyes; Microspheres; Myocardial Infarction; Risk; Serum Albumin; Thiazoles

1982
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6

    Topics: Alzheimer Disease; Animals; Apolipoproteins E; Benzothiazoles; Disease Models, Animal; Genetic Predisposition to Disease; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Nerve Degeneration; Neurites; Plaque, Amyloid; Protein Isoforms; Thiazoles; Time Factors

2000
Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Feb-01, Volume: 21, Issue:3

    Topics: Alzheimer Disease; Animals; Benzothiazoles; Disease Models, Animal; Disease Progression; Feedback; Fluorescent Dyes; Image Processing, Computer-Assisted; Male; Mice; Mice, Transgenic; Microscopy; Plaque, Amyloid; Thiazoles

2001
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.
    Neuroscience, 2001, Volume: 104, Issue:3

    Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine

2001
Statistical aspects of quantitative image analysis of beta-amyloid in the APP(V717F) transgenic mouse model of Alzheimer's disease.
    Journal of neuroscience methods, 2001, Jul-30, Volume: 108, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cell Count; Data Interpretation, Statistical; Disease Models, Animal; Hippocampus; Image Processing, Computer-Assisted; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Plaque, Amyloid; Reproducibility of Results; Statistical Distributions; Thiazoles

2001
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.
    Neurobiology of disease, 2001, Volume: 8, Issue:6

    Topics: Animals; Benzothiazoles; Brain; Cerebral Cortex; Coloring Agents; Congo Red; Disease Models, Animal; Female; Gene Expression Regulation; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutation, Missense; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Protein Structure, Secondary; tau Proteins; Thiazoles; Transfection; Ubiquitin

2001
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
    Journal of neuroscience research, 2001, Nov-15, Volume: 66, Issue:4

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Congo Red; Disease Models, Animal; Gene Expression Regulation, Developmental; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Insertional; Mutation; Neurites; Neurons; Peptide Fragments; Plaque, Amyloid; Presynaptic Terminals; Promoter Regions, Genetic; Thiazoles

2001
Amyloid-beta deposits in the cerebral cortex of the aged common marmoset (Callithrix jacchus): incidence and chemical composition.
    Acta neuropathologica, 2002, Volume: 103, Issue:1

    Topics: Aging; alpha 1-Antichymotrypsin; Amyloid beta-Peptides; Animals; Apolipoproteins E; Benzothiazoles; Brain Diseases; Callithrix; Cerebral Cortex; Cholinesterases; Disease Models, Animal; Female; Incidence; Male; Neurites; Peptide Fragments; Plaque, Amyloid; Survival Analysis; Thiazoles

2002
[Effect of TFX (Polfa) on the course of experimental bacterial infections in mice treated with ciprofloxacin, amikacin and cefoperazone].
    Pneumonologia i alergologia polska, 1992, Volume: 60, Issue:1-2

    Topics: Amikacin; Animals; Cefoperazone; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Escherichia coli Infections; Female; Male; Mice; Mice, Inbred BALB C; Staphylococcal Infections; Staphylococcus aureus; Thymus Extracts

1992