Page last updated: 2024-08-22

thioflavin t and Diabetes Mellitus, Type 2

thioflavin t has been researched along with Diabetes Mellitus, Type 2 in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's4 (22.22)29.6817
2010's11 (61.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Abioye, RO; Okagu, OD; Udenigwe, CC1
Arnold, AA; Bourgault, S; Marcotte, I; Nguyen, PT; Sebastiao, M; Zottig, X1
Davis, TP; Ding, F; Kakinen, A; Ke, PC; Nowell, CJ; Pilkington, EH; Sun, Y; Wang, B; Wang, M; Xing, Y1
Bahramikia, S; Yazdanparast, R1
Kapurniotu, A; Velkova, A; Yan, LM1
Abedini, A; Cao, P; Raleigh, DP; Schmidt, AM; Tu, LH; Wang, H; Zhang, X1
Viles, JH; Younan, ND1
Schlein, M1
Baum, L; Chan, JC; Gu, XM; Guan, J; He, L; Lai, FM; Sui, Y; Tong, PC; Wong, HK; Zhao, HL1
Cho, WJ; Jena, BP; Jeremic, AM1
Grasso, DM; La Rosa, C; Marletta, G; Scalisi, S; Sciacca, MF; Zhavnerko, G1
Abedini, A; Meng, F; Plesner, A; Raleigh, DP; Verchere, CB1
Noormägi, A; Palumaa, P; Primar, K; Tõugu, V1
Davies, HA; Madine, J; Middleton, DA1
Cheng, B; Gong, H; Huang, K; Li, C; Li, T; Sun, Y; Zhang, X; Zheng, L1
Gupta, R; Marek, P; Raleigh, DP1
Butler, PC; Eberhardt, NL; Kudva, YC; Mueske, C1
Clark, A; Fraser, PE; Gross, M; Higham, CE; Jaikaran, ET; Serpell, LC; Zurdo, J1

Reviews

1 review(s) available for thioflavin t and Diabetes Mellitus, Type 2

ArticleYear
Insulin Formulation Characterization-the Thioflavin T Assays.
    The AAPS journal, 2017, Volume: 19, Issue:2

    Topics: Amyloid; Benzothiazoles; Biological Assay; Diabetes Mellitus, Type 2; Drug Design; Fluorescent Dyes; Humans; Hypoglycemic Agents; Insulin; Thiazoles

2017

Other Studies

17 other study(ies) available for thioflavin t and Diabetes Mellitus, Type 2

ArticleYear
Disaggregation of Islet Amyloid Polypeptide Fibrils as a Potential Anti-Fibrillation Mechanism of Tetrapeptide TNGQ.
    International journal of molecular sciences, 2022, Feb-10, Volume: 23, Issue:4

    Topics: Amyloid; Amyloid beta-Peptides; Benzothiazoles; Diabetes Mellitus, Type 2; Humans; Hydrophobic and Hydrophilic Interactions; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Kinetics; Static Electricity

2022
Identification of transmissible proteotoxic oligomer-like fibrils that expand conformational diversity of amyloid assemblies.
    Communications biology, 2021, 08-05, Volume: 4, Issue:1

    Topics: Amyloid; Amyloidosis; Benzothiazoles; Cell Death; Diabetes Mellitus, Type 2; Hydrophobic and Hydrophilic Interactions; Islet Amyloid Polypeptide

2021
Lysophosphatidylcholine modulates the aggregation of human islet amyloid polypeptide.
    Physical chemistry chemical physics : PCCP, 2017, Nov-22, Volume: 19, Issue:45

    Topics: alpha-Synuclein; Benzothiazoles; Diabetes Mellitus, Type 2; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Kinetics; Lysophosphatidylcholines; Microscopy, Electron, Transmission; Molecular Dynamics Simulation; Thiazoles

2017
Inhibition of human islet amyloid polypeptide or amylin aggregation by two manganese-salen derivatives.
    European journal of pharmacology, 2013, May-05, Volume: 707, Issue:1-3

    Topics: Amyloid; Anilino Naphthalenesulfonates; Antioxidants; Benzothiazoles; Cell Line, Tumor; Cell Survival; Diabetes Mellitus, Type 2; Ethylenediamines; Fluorescent Dyes; Humans; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Molecular Docking Simulation; Neuroblastoma; Organometallic Compounds; Salicylates; Thiazoles

2013
Molecular characterization of the hetero-assembly of β-amyloid peptide with islet amyloid polypeptide.
    Current pharmaceutical design, 2014, Volume: 20, Issue:8

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Amyloidosis; Animals; Benzothiazoles; Cell Survival; Circular Dichroism; Diabetes Mellitus, Type 2; Islet Amyloid Polypeptide; Kinetics; Microscopy, Electron, Transmission; Molecular Sequence Data; PC12 Cells; Peptide Fragments; Protein Binding; Protein Folding; Protein Multimerization; Rats; Spectrometry, Fluorescence; Thiazoles

2014
Islet amyloid polypeptide toxicity and membrane interactions.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-26, Volume: 110, Issue:48

    Topics: Amino Acid Sequence; Amyloid; Animals; Benzothiazoles; Biophysics; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Membranes, Artificial; Microscopy, Electron, Transmission; Molecular Sequence Data; Oxazines; Rats; Species Specificity; Thiazoles; Xanthenes

2013
A Comparison of Three Fluorophores for the Detection of Amyloid Fibers and Prefibrillar Oligomeric Assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid).
    Biochemistry, 2015, Jul-21, Volume: 54, Issue:28

    Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Amyloid beta-Peptides; Anilino Naphthalenesulfonates; Benzothiazoles; Diabetes Mellitus, Type 2; Fluorescent Dyes; Humans; Islet Amyloid Polypeptide; Molecular Sequence Data; Spectrometry, Fluorescence; Thiazoles

2015
Amyloid oligomers in diabetic and nondiabetic human pancreas.
    Translational research : the journal of laboratory and clinical medicine, 2009, Volume: 153, Issue:1

    Topics: Aged; Amyloid; Apoptosis; Benzothiazoles; Biomarkers; Blotting, Western; Caspase 3; Diabetes Mellitus, Type 2; Female; Fluorescent Antibody Technique, Indirect; Humans; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Protein Multimerization; Thiazoles

2009
Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus.
    Methods in cell biology, 2008, Volume: 90

    Topics: Aluminum Silicates; Amyloid; Animals; Benzothiazoles; Biological Assay; Cell Membrane; Cholesterol; Circular Dichroism; Diabetes Mellitus, Type 2; Fluorescence; Humans; Imaging, Three-Dimensional; Islet Amyloid Polypeptide; Liposomes; Microscopy, Atomic Force; Models, Biological; Nanotechnology; Phase Transition; Phospholipids; Protein Structure, Quaternary; Protein Structure, Secondary; Rats; Solutions; Surface Properties; Thiazoles

2008
Self-assembling pathway of HiApp fibrils within lipid bilayers.
    Chembiochem : a European journal of chemical biology, 2010, Sep-03, Volume: 11, Issue:13

    Topics: Benzothiazoles; Diabetes Mellitus, Type 2; Fluoresceins; Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Microscopy, Atomic Force; Spectrometry, Fluorescence; Thiazoles

2010
The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.
    Biochemistry, 2010, Sep-21, Volume: 49, Issue:37

    Topics: alpha-Synuclein; Amyloid; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Catechin; Cell Culture Techniques; Diabetes Mellitus, Type 2; Flavonoids; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Phenols; Polyphenols; Protease Nexins; Rats; Receptors, Cell Surface; Thiazoles

2010
Interference of low-molecular substances with the thioflavin-T fluorescence assay of amyloid fibrils.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:1

    Topics: Amyloid; Amyloid beta-Peptides; Azure Stains; Benzothiazoles; Biological Assay; Diabetes Mellitus, Type 2; False Positive Reactions; Fluorescent Dyes; Humans; Insulin; Kinetics; Neurodegenerative Diseases; Protein Structure, Secondary; Spectrometry, Fluorescence; Tannins; Thiazoles

2012
Solid-state NMR reveals differences in the packing arrangements of peptide aggregates derived from the aortic amyloid polypeptide medin.
    Journal of peptide science : an official publication of the European Peptide Society, 2012, Volume: 18, Issue:1

    Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Antigens, Surface; Aorta; Benzothiazoles; Biomarkers; Diabetes Mellitus, Type 2; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron; Milk Proteins; Molecular Sequence Data; Neurodegenerative Diseases; Peptide Fragments; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Thiazoles

2012
Bisphenol A accelerates toxic amyloid formation of human islet amyloid polypeptide: a possible link between bisphenol A exposure and type 2 diabetes.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Air Pollutants, Occupational; Amino Acid Sequence; Animals; Benzhydryl Compounds; Benzothiazoles; Cell Line, Tumor; Cell Membrane; Circular Dichroism; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Humans; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Microscopy, Electron, Transmission; Molecular Sequence Annotation; Oxidative Stress; Phenols; Protein Folding; Protein Structure, Secondary; Rats; Thiazoles

2013
The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation.
    Chembiochem : a European journal of chemical biology, 2008, Jun-16, Volume: 9, Issue:9

    Topics: Alanine; Amino Acid Sequence; Amyloid; Benzothiazoles; Diabetes Mellitus, Type 2; Fluorescence; Fluorescent Dyes; Humans; Islet Amyloid Polypeptide; Kinetics; Molecular Sequence Data; Nitriles; Phenylalanine; Point Mutation; Protein Binding; Thiazoles; Time Factors

2008
A novel assay in vitro of human islet amyloid polypeptide amyloidogenesis and effects of insulin secretory vesicle peptides on amyloid formation.
    The Biochemical journal, 1998, May-01, Volume: 331 ( Pt 3)

    Topics: Amyloid; Benzothiazoles; C-Peptide; Cytoplasmic Granules; Diabetes Mellitus, Type 2; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Insulin; Islets of Langerhans; Kinetics; Microscopy, Electron; Peptide Fragments; Proinsulin; Temperature; Thiazoles

1998
Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.
    Journal of molecular biology, 2001, May-04, Volume: 308, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Amyloid; Amyloidosis; Animals; Benzothiazoles; Circular Dichroism; Diabetes Mellitus, Type 2; Humans; Hydrogen-Ion Concentration; Islet Amyloid Polypeptide; Islets of Langerhans; Microscopy, Electron; Molecular Sequence Data; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Spectroscopy, Fourier Transform Infrared; Thiazoles; X-Ray Diffraction

2001