Page last updated: 2024-08-22

thioflavin t and Aging

thioflavin t has been researched along with Aging in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's6 (18.18)18.2507
2000's14 (42.42)29.6817
2010's9 (27.27)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Genov, M; Hummel, T; Kasture, A; Krenn, L; Moloney, M; Pretsch, A; Pretsch, D; Rollinger, JM; Schmid, A; Wöhrer, T1
Fujii, N; Hachiya, N; Magami, K; Morikawa, K; Takata, T1
Anderson, A; Barton, SM; Gore, JC; Janve, VA; Matsubara, JA; McClure, R; Pham, W1
Buxbaum, JN; Reixach, N; Zhao, L1
Casadei, N; De Heer, R; Kahle, PJ; Klucken, J; Krüger, R; Lucas, JJ; Noldus, LP; Nuber, S; Pöhler, AM; Riess, O; Schwedhelm, I; Spruijt, B; Tomás-Zapico, C; Torres-Peraza, J; Witz, A; Zamolo, I1
Bartos, A; Gazova, Z; Kotoucova, J; Kristofikova, Z; Ricny, J; Ripova, D; Siposova, K; Sirova, J1
Ashe, KH; Borchelt, DR; Forster, CL; Hemmy, LS; Huang, ES; Kuskowski, MA; Liu, P; McNellis, BM; Rao, ER; Reichl, JH; Vassar, R; Zahs, KR1
Kellaway, LA; Kotwal, GJ; Kulkarni, AP; Pillay, NS1
Kovacs, B; Lumayag, S; Mufson, EJ; Perez, SE; Xu, S1
Carroll, VL; Dickson, TC; Halliday, GM; King, AE; Shepherd, CE; Sokolova, A; Vickers, JC; Woodhouse, A1
Cassell, MD; Ding, SL; Poremba, A; Van Hoesen, GW1
Huang, W; Lei, H; Wang, X; Xu, W; Zhan, Y; Zhang, S1
Alavez, S; Klang, IM; Lithgow, GJ; Vantipalli, MC; Zucker, DJ1
Alavez, S; Lithgow, GJ1
Gharibyan, AL; Morozova-Roche, LA; Raveh, D1
Capsoni, S; Cattaneo, A; Giannotta, S1
Bacskai, BJ; D'Amore, JD; Hyman, BT; Kajdasz, ST; McLellan, ME; Stern, EA1
SJAARDA, JR; WALFORD, RL1
Berry, Y; Carver, JA; Dobson, CM; Luisi, B; MacPhee, CE; Meehan, S1
Minichiello, L; Unsicker, K; von Bohlen und Halbach, O1
Reiman, EM; Schneider, L; Valla, J1
Arendt, T; Bigl, V; Brückner, MK; Marcova, L1
Buée, L; Buée-Scherrer, V; Delacourte, A; Marugg, RA; Morrison, JH; Riederer, BM; Vickers, JC1
Aimi, Y; Kawamata, T; McGeer, EG; McGeer, PL; Yasuhara, O1
Johnson-Wood, K; Lin, C; Mallory, M; Masliah, E; McConlogue, L; Mucke, L; Wyss-Coray, T1
Beffert, U; Poirier, J1
Azizeh, BY; Cotman, CW; Cribbs, DH; Head, E; Lott, IT; Tenner, AJ1
Duff, K; La Francois, J; Matsuoka, Y; Picciano, M1
Emson, PC; Iritani, S; Niizato, K1
Mallory, M; Mante, M; Masliaha, E; Rockenstein, E; Sisk, A1
Geula, C; Nagykery, N; Wu, CK1
Chen, WH; Higuchi, K; Hosokawa, M; Matsushima, K; Naiki, H; Shimada, A; Takeda, T1
Brion, JP; Delaère, P; Duyckaerts, C; Hauw, JJ; Poulain, V1

Other Studies

33 other study(ies) available for thioflavin t and Aging

ArticleYear
Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans.
    Scientific reports, 2020, 07-16, Volume: 10, Issue:1

    Topics: Aging; alpha-Synuclein; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Benzothiazoles; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Clioquinol; Disease Models, Animal; Emodin; Gene Knockdown Techniques; Homeostasis; Metallothionein; Metals; Neuroprotective Agents; Parkinson Disease; Quercetin; Signal Transduction

2020
Isomerization of Asp is essential for assembly of amyloid-like fibrils of αA-crystallin-derived peptide.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Aging; Alanine; alpha-Crystallin A Chain; Amino Acid Sequence; Amino Acid Substitution; Amyloid; Aspartic Acid; Benzothiazoles; Cataract; Fluorescent Dyes; Humans; Hydrophobic and Hydrophilic Interactions; Isoaspartic Acid; Isomerism; Lens, Crystalline; Microscopy, Electron; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Processing, Post-Translational; Static Electricity

2021
Lipopolysaccharide Induced Opening of the Blood Brain Barrier on Aging 5XFAD Mouse Model.
    Journal of Alzheimer's disease : JAD, 2019, Volume: 67, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Biological Availability; Blood-Brain Barrier; Ferric Compounds; Humans; Inflammation; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nanoparticles; Permeability; Plaque, Amyloid

2019
Age-related oxidative modifications of transthyretin modulate its amyloidogenicity.
    Biochemistry, 2013, Mar-19, Volume: 52, Issue:11

    Topics: Age Factors; Aging; Amyloid; Amyloidosis; Benzothiazoles; Cell Line; Humans; Myocytes, Cardiac; Oxidation-Reduction; Point Mutation; Prealbumin; Protein Carbonylation; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Resveratrol; Stilbenes; Thiazoles

2013
Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice.
    Human molecular genetics, 2014, Feb-01, Volume: 23, Issue:3

    Topics: Aging; alpha-Synuclein; Animals; Autophagy; Benzothiazoles; Brain; Carrier Proteins; Gene Expression; Humans; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Parkinson Disease; Protein Folding; Solubility; Thiazoles; Ubiquitin

2014
Effects of ferrofluid and phytoalexin spirobrassinin on thioflavin-T-based fluorescence in cerebrospinal fluid of the elderly and multiple sclerosis patients.
    Neurochemical research, 2014, Volume: 39, Issue:8

    Topics: Adult; Aged; Aging; Benzothiazoles; Chlorides; Female; Ferric Compounds; Ferrous Compounds; Fluorescence; Fluorescent Dyes; Humans; Male; Middle Aged; Multiple Sclerosis; Spiro Compounds; Thiazoles

2014
Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 56, Issue:2

    Topics: Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Humans; Male; Mice, Transgenic; Plaque, Amyloid; Species Specificity; Thiazoles

2017
Intracranial administration of vaccinia virus complement control protein in Mo/Hu APPswe PS1dE9 transgenic mice at an early age shows enhanced performance at a later age using a cheese board maze test.
    Biogerontology, 2008, Volume: 9, Issue:6

    Topics: Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Association Learning; Behavior, Animal; Benzothiazoles; Complement System Proteins; Conditioning, Psychological; Disease Models, Animal; Genotype; Injections; Maze Learning; Mice; Mice, Transgenic; Reversal Learning; Space Perception; Thiazoles; Viral Proteins

2008
Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antigens, Differentiation; Benzothiazoles; Choline O-Acetyltransferase; Disease Models, Animal; Electroretinography; Female; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Glial Fibrillary Acidic Protein; Gliosis; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Presenilin-1; Retina; Retinal Diseases; Syntaxin 1; Thiazoles

2009
Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease.
    Acta neuropathologica, 2009, Volume: 117, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Autopsy; Benzothiazoles; Blotting, Western; Cohort Studies; Cytoskeleton; Humans; Immunohistochemistry; Middle Aged; Neurofibrillary Tangles; Phosphorylation; Plaque, Amyloid; Presenilin-1; Severity of Illness Index; tau Proteins; Thiazoles

2009
Parcellation of human temporal polar cortex: a combined analysis of multiple cytoarchitectonic, chemoarchitectonic, and pathological markers.
    The Journal of comparative neurology, 2009, Jun-20, Volume: 514, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Antigens, Nuclear; Benzothiazoles; Female; Histocytochemistry; Humans; Immunohistochemistry; Male; Nerve Tissue Proteins; Plant Lectins; Pyramidal Cells; Receptors, N-Acetylglucosamine; Tauopathies; Temporal Lobe; Thiazoles

2009
Reduction of hippocampal N-acetyl aspartate level in aged APP(Swe)/PS1(dE9) transgenic mice is associated with degeneration of CA3 pyramidal neurons.
    Journal of neuroscience research, 2010, Nov-01, Volume: 88, Issue:14

    Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Aspartic Acid; Benzothiazoles; CA1 Region, Hippocampal; Creatine; Disease Models, Animal; Down-Regulation; Female; Humans; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Transgenic; Nerve Degeneration; Plaque, Amyloid; Presenilin-1; Pyramidal Cells; Thiazoles

2010
Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.
    Nature, 2011, Apr-14, Volume: 472, Issue:7342

    Topics: Aging; Amyloid; Amyloid beta-Peptides; Animals; Autophagy; Benzothiazoles; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Curcumin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Forkhead Transcription Factors; Homeostasis; Humans; Longevity; Molecular Chaperones; Paralysis; Phenotype; Proteasome Endopeptidase Complex; Protein Binding; Proteins; Survival Analysis; Thiazoles; Transcription Factors

2011
A new look at old compounds.
    Aging, 2011, Volume: 3, Issue:4

    Topics: Aging; Animals; Benzothiazoles; Disease; Fluorescent Dyes; Homeostasis; Humans; Proteins; Thiazoles

2011
S100A8/A9 amyloidosis in the ageing prostate: relating ex vivo and in vitro studies.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 849

    Topics: Aging; Amyloid; Benzothiazoles; Blotting, Western; Calgranulin A; Calgranulin B; Chromatography, Liquid; Humans; Male; Prostate; Protein Multimerization; Protein Structure, Secondary; Spectrometry, Mass, Electrospray Ionization; Staining and Labeling; Thiazoles

2012
Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies.
    Molecular and cellular neurosciences, 2002, Volume: 21, Issue:1

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autoantibodies; Benzothiazoles; Brain; Cerebellum; Disease Models, Animal; Locus Coeruleus; Mice; Mice, Transgenic; Neostriatum; Nerve Growth Factor; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; Signal Transduction; Silver Staining; Thiazoles

2002
In vivo multiphoton imaging of a transgenic mouse model of Alzheimer disease reveals marked thioflavine-S-associated alterations in neurite trajectories.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:2

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Axons; Benzothiazoles; Cerebral Cortex; Dendrites; Dextrans; Disease Models, Animal; Fluorescent Dyes; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence, Multiphoton; Neurites; Neuropil; Plaque, Amyloid; Thiazoles

2003
INCREASE OF THIOFLAVINE-T-STAINING MATERIAL (AMYLOID) IN HUMAN TISSUES WITH AGE.
    Journal of gerontology, 1964, Volume: 19

    Topics: Aging; Amyloid; Benzothiazoles; Cerebral Cortex; Fluorescent Dyes; Geriatrics; Histocytochemistry; Humans; Myocardium; Spleen; Staining and Labeling; Thiazoles

1964
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation.
    The Journal of biological chemistry, 2004, Jan-30, Volume: 279, Issue:5

    Topics: Aging; alpha-Crystallins; Amyloid; Animals; Benzothiazoles; beta-Crystallins; Cataract; Cattle; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; gamma-Crystallins; Guanidine; Hydrogen-Ion Concentration; Lens, Crystalline; Microscopy, Electron; Protein Folding; Protein Processing, Post-Translational; Temperature; Thiazoles; X-Ray Diffraction

2004
Haploinsufficiency for trkB and trkC receptors induces cell loss and accumulation of alpha-synuclein in the substantia nigra.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:12

    Topics: Aging; Alkaloids; alpha-Synuclein; Animals; Axons; Benzothiazoles; Brain-Derived Neurotrophic Factor; Crosses, Genetic; Densitometry; Dopamine; Fluorescent Dyes; Heterozygote; Immunohistochemistry; Indoles; Ligands; Male; Mice; Mutation; Neurons; Parkinson Disease; Phenotype; Quinolines; Receptor, trkB; Receptor, trkC; Signal Transduction; Substantia Nigra; Thiazoles; Tyrosine 3-Monooxygenase

2005
Age- and transgene-related changes in regional cerebral metabolism in PSAPP mice.
    Brain research, 2006, Oct-20, Volume: 1116, Issue:1

    Topics: Aging; Amyloid beta-Protein Precursor; Animals; Autoradiography; Benzothiazoles; Brain; Brain Chemistry; Fluorescent Dyes; Fluorodeoxyglucose F18; Humans; Mice; Microscopy, Fluorescence; Presenilin-1; Radiopharmaceuticals; Thiazoles; Transgenes

2006
Dendritic reorganisation in the basal forebrain under degenerative conditions and its defects in Alzheimer's disease. II. Ageing, Korsakoff's disease, Parkinson's disease, and Alzheimer's disease.
    The Journal of comparative neurology, 1995, Jan-09, Volume: 351, Issue:2

    Topics: Adult; Aged; Aging; Alcohol Amnestic Disorder; Alzheimer Disease; Benzothiazoles; Cell Count; Dendrites; Female; Fluorescent Dyes; Histocytochemistry; Humans; Male; Middle Aged; Nerve Degeneration; Neuronal Plasticity; Parkinson Disease; Prosencephalon; Staining and Labeling; Thiazoles

1995
Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease.
    Neuroscience, 1994, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Benzothiazoles; Female; Hippocampus; Humans; Immunoblotting; Immunohistochemistry; Male; Middle Aged; Neurofilament Proteins; Neurons; Reference Values; Thiazoles

1994
Two types of dystrophic neurites in senile plaques of Alzheimer disease and elderly non-demented cases.
    Neuroscience letters, 1994, Apr-25, Volume: 171, Issue:1-2

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Antigens; Benzothiazoles; Cerebral Cortex; Chromogranin A; Chromogranins; Fluorescent Dyes; Humans; Immunohistochemistry; Neurites; tau Proteins; Thiazoles; Ubiquitins

1994
Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease.
    Nature, 1997, Oct-09, Volume: 389, Issue:6651

    Topics: Aged; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Astrocytes; Benzothiazoles; Brain; Cerebral Amyloid Angiopathy; Humans; Mice; Mice, Inbred BALB C; Mice, Transgenic; Thiazoles; Transforming Growth Factor beta

1997
ApoE associated with lipid has a reduced capacity to inhibit beta-amyloid fibril formation.
    Neuroreport, 1998, Oct-05, Volume: 9, Issue:14

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Apolipoproteins E; Benzothiazoles; Cholesterol; Fluorescent Dyes; Humans; Neurofibrillary Tangles; Thiazoles

1998
Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down Syndrome.
    Neurobiology of disease, 2001, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Amyloid beta-Peptides; Benzothiazoles; Brain; Complement C1q; Down Syndrome; Encephalitis; Female; Humans; Immunohistochemistry; Male; Microglia; Middle Aged; Neurofibrillary Tangles; Neurons; Plaque, Amyloid; Thiazoles

2001
Fibrillar beta-amyloid evokes oxidative damage in a transgenic mouse model of Alzheimer's disease.
    Neuroscience, 2001, Volume: 104, Issue:3

    Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine

2001
Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2001, Volume: 21, Issue:3

    Topics: Age of Onset; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Benzothiazoles; Calbindin 1; Calbindins; Female; Fluorescent Dyes; Hippocampus; Humans; Immunohistochemistry; Male; Middle Aged; Neurofibrillary Tangles; Plaque, Amyloid; Pyramidal Cells; S100 Calcium Binding Protein G; Thiazoles

2001
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
    Journal of neuroscience research, 2001, Nov-15, Volume: 66, Issue:4

    Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzothiazoles; Brain; Congo Red; Disease Models, Animal; Gene Expression Regulation, Developmental; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Microscopy, Electron; Mutagenesis, Insertional; Mutation; Neurites; Neurons; Peptide Fragments; Plaque, Amyloid; Presynaptic Terminals; Promoter Regions, Genetic; Thiazoles

2001
Amyloid-beta deposits in the cerebral cortex of the aged common marmoset (Callithrix jacchus): incidence and chemical composition.
    Acta neuropathologica, 2002, Volume: 103, Issue:1

    Topics: Aging; alpha 1-Antichymotrypsin; Amyloid beta-Peptides; Animals; Apolipoproteins E; Benzothiazoles; Brain Diseases; Callithrix; Cerebral Cortex; Cholinesterases; Disease Models, Animal; Female; Incidence; Male; Neurites; Peptide Fragments; Plaque, Amyloid; Survival Analysis; Thiazoles

2002
Fluorometric examination of tissue amyloid fibrils in murine senile amyloidosis: use of the fluorescent indicator, thioflavine T.
    Laboratory investigation; a journal of technical methods and pathology, 1990, Volume: 62, Issue:6

    Topics: Aging; Amyloid; Amyloidosis; Animals; Benzothiazoles; Fluorescent Dyes; Liver; Mice; Mice, Inbred Strains; Spectrometry, Fluorescence; Spleen; Thiazoles

1990
Does amyloid precede paired helical filaments in the senile plaque? A study of 15 cases with graded intellectual status in aging and Alzheimer disease.
    Neuroscience letters, 1988, Sep-12, Volume: 91, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Amyloid; Benzothiazoles; Brain; Female; Humans; Immunohistochemistry; Intermediate Filaments; Staining and Labeling; Thiazoles

1988