thioctic acid has been researched along with Weight Gain in 14 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain." | 8.12 | Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression. ( Chaves Filho, AJM; Cunha, NL; De Oliveira, GMF; Gadelha Filho, CVJ; Jucá, PM; Macedo, DS; Oliveira, TQ; Soares, MVR; Vasconcelos, SMM; Viana, GA; Vieira, CFX, 2022) |
| "This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity." | 7.83 | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016) |
| "We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 7.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
| "Mirtazapine (MIRT) is a multi-target antidepressant used in treatment of severe depression with promising efficacy, but also with important side effects, mainly sedation and weight gain." | 4.12 | Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression. ( Chaves Filho, AJM; Cunha, NL; De Oliveira, GMF; Gadelha Filho, CVJ; Jucá, PM; Macedo, DS; Oliveira, TQ; Soares, MVR; Vasconcelos, SMM; Viana, GA; Vieira, CFX, 2022) |
| "This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity." | 3.83 | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016) |
| "We compared body weight and food intake among vehicle-, olanzapine-, and olanzapine plus ALA-treated mice, and measured hypothalamic AMP-activated protein kinase (AMPK) activity by detecting levels of Thr(172) and Ser(485/491) phosphorylation, which indicate activation and inhibition of AMPK, respectively." | 3.80 | Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine. ( Cho, HS; Jeong, J; Kim, E; Kim, H; Lee, BI; Lee, SK; Namkoong, K; Park, JY; Park, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Oliveira, TQ | 1 |
| Chaves Filho, AJM | 1 |
| Jucá, PM | 1 |
| Soares, MVR | 1 |
| Cunha, NL | 1 |
| Vieira, CFX | 1 |
| Gadelha Filho, CVJ | 1 |
| Viana, GA | 1 |
| De Oliveira, GMF | 1 |
| Macedo, DS | 1 |
| Vasconcelos, SMM | 1 |
| Wang, Y | 1 |
| Everaert, N | 1 |
| Song, Z | 1 |
| Decuypere, E | 1 |
| Vermeulen, D | 1 |
| Buyse, J | 1 |
| Panzhinskiy, E | 1 |
| Bashir, R | 1 |
| Bagchi, D | 1 |
| Nair, S | 1 |
| Kim, H | 1 |
| Park, M | 1 |
| Lee, SK | 1 |
| Jeong, J | 1 |
| Namkoong, K | 1 |
| Cho, HS | 2 |
| Park, JY | 2 |
| Lee, BI | 1 |
| Kim, E | 2 |
| Cheserek, MJ | 1 |
| Wu, G | 1 |
| Li, L | 2 |
| Karangwa, E | 1 |
| Shi, Y | 1 |
| Le, G | 1 |
| Kim, NW | 1 |
| Song, YM | 1 |
| Cheon, KA | 1 |
| Kim, SJ | 1 |
| Prieto-Hontoria, PL | 2 |
| Pérez-Matute, P | 2 |
| Fernández-Galilea, M | 2 |
| Barber, A | 1 |
| Martínez, JA | 1 |
| Moreno-Aliaga, MJ | 2 |
| Sohaib, M | 1 |
| Anjum, FM | 1 |
| Khan, MI | 1 |
| Arshad, MS | 1 |
| Shahid, M | 1 |
| Alfredo Martínez, J | 1 |
| Ide, T | 1 |
| Azechi, A | 1 |
| Kitade, S | 1 |
| Kunimatsu, Y | 1 |
| Suzuki, N | 1 |
| Nakajima, C | 1 |
| Imik, H | 1 |
| Ozlu, H | 1 |
| Gumus, R | 1 |
| Atasever, MA | 1 |
| Urcar, S | 1 |
| Atasever, M | 1 |
| LOMBARDI, D | 1 |
| Thirunavukkarasu, V | 1 |
| Anuradha, CV | 1 |
| Schmidt, TB | 1 |
| Brown, MS | 1 |
| Larson, RL | 1 |
| Kleiboeker, SB | 1 |
| Olson, KC | 1 |
| Keisler, D | 1 |
| Carroll, JA | 1 |
| Berg, EP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cellular and Molecular Effects of Lipoic Acid and Eicosapentaenoic Acid (EPA) on Adipose Tissue: Potential Application in Human Obesity[NCT01138774] | 103 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for thioctic acid and Weight Gain
| Article | Year |
|---|---|
Adjunctive α-lipoic acid reduces weight gain compared with placebo at 12 weeks in schizophrenic patients treated with atypical antipsychotics: a double-blind randomized placebo-controlled study.
Topics: Adult; Antioxidants; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; H | 2016 |
Effect of dietary lipoic acid on metabolic hormones and acute-phase proteins during challenge with infectious bovine rhinotracheitis virus in cattle.
Topics: Acute-Phase Proteins; Animal Feed; Animals; Cattle; Dietary Fats; Infectious Bovine Rhinotracheitis; | 2006 |
12 other studies available for thioctic acid and Weight Gain
| Article | Year |
|---|---|
Lipoic acid prevents mirtazapine-induced weight gain in mice without impairs its antidepressant-like action in a neuroendocrine model of depression.
Topics: Animals; Antidepressive Agents; Antioxidants; Behavior, Animal; Cognitive Dysfunction; Corticosteron | 2022 |
Alpha-lipoic acid impairs body weight gain of young broiler chicks via modulating peripheral AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Chickens; Male; Principal Component Analysis; Protein Kinase | 2017 |
Effect of Curcumin and α-Lipoic Acid in Attenuating Weight Gain and Adiposity.
Topics: Adiposity; Animals; Curcumin; Diet, High-Fat; Male; Mice; Mice, Inbred C57BL; Thioctic Acid; Weight | 2019 |
Phosphorylation of hypothalamic AMPK on serine(485/491) related to sustained weight loss by alpha-lipoic acid in mice treated with olanzapine.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Antipsychotic Agents; Benzodiazepines; | 2014 |
Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.
Topics: Animals; Anti-Obesity Agents; Antihypertensive Agents; Antioxidants; Biomarkers; Cardiotonic Agents; | 2016 |
Lipoic acid prevents body weight gain induced by a high fat diet in rats: effects on intestinal sugar transport.
Topics: Adipose Tissue; Animals; Carbohydrate Metabolism; Dietary Fats; Eating; Intestinal Absorption; Male; | 2009 |
Enhancement of lipid stability of broiler breast meat and meat products fed on alpha lipoic acid and alpha tocopherol acetate supplemented feed.
Topics: alpha-Tocopherol; Animal Feed; Animals; Biphenyl Compounds; Chickens; Food Preservation; Food Qualit | 2012 |
Effects of lipoic acid on AMPK and adiponectin in adipose tissue of low- and high-fat-fed rats.
Topics: Adiponectin; Adipose Tissue, Brown; Adipose Tissue, White; Adiposity; AMP-Activated Protein Kinases; | 2013 |
Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats.
Topics: Animals; Appetite Depressants; Carnitine; Dietary Supplements; Dioxoles; Fatty Acids; Gene Expressio | 2013 |
Effects of ascorbic acid and α-lipoic acid on performance and meat quality of broilers subjected to heat stress.
Topics: Animals; Antioxidants; Ascorbic Acid; Chickens; Diet; Dietary Supplements; Feeding Behavior; Female; | 2012 |
[Action of thioctic acid and reserpine on weight increase in the chick].
Topics: Animals; Body Weight; Body Weights and Measures; Chickens; Reserpine; Thioctic Acid; Weight Gain | 1962 |
Influence of alpha-lipoic acid on lipid peroxidation and antioxidant defence system in blood of insulin-resistant rats.
Topics: Animals; Antioxidants; Blood Glucose; Diet; Erythrocytes; Fructose; Glucose Tolerance Test; Insulin; | 2004 |