Page last updated: 2024-10-19

thioctic acid and Vitamin B Deficiency

thioctic acid has been researched along with Vitamin B Deficiency in 4 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Vitamin B Deficiency: A condition due to deficiency in any member of the VITAMIN B COMPLEX. These B vitamins are water-soluble and must be obtained from the diet because they are easily lost in the urine. Unlike the lipid-soluble vitamins, they cannot be stored in the body fat.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rowin, J1
GRIGNANI, F1
BERNARDINI, V1
OTANI, M1
GAL, EM1
RAZEVSKA, DE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dose Finding and Tolerability Study of Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Peripheral Neuropathy[NCT01313117]Phase 1/Phase 29 participants (Actual)Interventional2012-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Cumulative Rate of Adverse Events

(NCT01313117)
Timeframe: 4 months

Interventionparticipants (Number)
Alpha Lipoic Acid9

Identification of the Optimal Dose of ALA Based on Acceptable Adverse Event(AE) Profile

Based on acceptable adverse event (AE) profile and continual reassessment method dose escalation. (NCT01313117)
Timeframe: 4 months

Interventionmg (Number)
Alpha Lipoic Acid500

Proportion of Patients Who Complete the Proposed Regimen of Daily ALA

(NCT01313117)
Timeframe: 4 months

Interventionparticipants (Number)
Alpha Lipoic Acid7

Reviews

1 review available for thioctic acid and Vitamin B Deficiency

ArticleYear
Integrative neuromuscular medicine: Neuropathy and neuropathic pain: Consider the alternatives.
    Muscle & nerve, 2019, Volume: 60, Issue:2

    Topics: Acetylcarnitine; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Diet; Diet Therapy; Dietary Supp

2019

Other Studies

3 other studies available for thioctic acid and Vitamin B Deficiency

ArticleYear
[Metabolic effects of thioctic acid in rats fed a vitamin B1 deficient diet].
    Archivio per le scienze mediche, 1958, Volume: 105, Issue:5

    Topics: Animals; Cholelithiasis; Diet; Rats; Thiamine; Thiamine Deficiency; Thioctic Acid; Vitamin B Deficie

1958
[Experimental studies on the tissue respiration, particularly on the TCA-cycle of isolated liver and diaphragm. 3. Studies on the O2 consumption of liver homogenate and diaphragm, taken from the thiamine deficient rats, response of Qo2 to panthotenic acid
    Naika hokan. Japanese archives of internal medicine, 1961, Volume: 8

    Topics: Animals; Citric Acid Cycle; Diaphragm; Liver; Metabolism; Muscles; Pantothenic Acid; Phosphates; Rat

1961
Studies on the in vivo metabolism of lipoic acid. 1. The fate of DL-lipoic acid-S35 in normal and thiamine-deficient rats.
    Archives of biochemistry and biophysics, 1960, Volume: 89

    Topics: Animals; Biochemical Phenomena; Lipid Metabolism; Rats; Thiamine; Thioctic Acid; Vitamin B Deficienc

1960