Page last updated: 2024-10-19

thioctic acid and Sterility, Male

thioctic acid has been researched along with Sterility, Male in 16 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Research Excerpts

ExcerptRelevanceReference
"Varicocele is a high incidence and is considered to be the most common and correctable cause of male infertility."3.11Effects of alpha-lipoic acid on sperm quality in patients with varicocele-related male infertility: study protocol for a randomized controlled clinical trial. ( Deng, W; Liu, QL; Wang, C; Wang, S; Wei, Y; Yang, B; Zhang, H; Zhang, QF, 2022)
" Stimulation of spermatogenesis using the antioxidant complex SpermActin Forte is an effective and safe method of treating male infertility."2.90[Double-blind, randomized placebo-controlled study of efficiency and safety of complex acetyl-L-carnitine, L-carnitine fumarate and alpha-lipoic acid (Spermactin Forte) for treatment of male infertility]. ( Gamidov, SI; Ovchinnikov, RI; Popova, AY, 2019)
") either alone or combined with alpha lipoic acid (ALA) (50 mg/kg b."1.48Effects of ivermectin and its combination with alpha lipoic acid on expression of IGFBP-3 and HSPA1 genes and male rat fertility. ( Abd El Naby, WSH; El-Maddawy, ZK, 2018)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.25)29.6817
2010's10 (62.50)24.3611
2020's5 (31.25)2.80

Authors

AuthorsStudies
Zhang, QF2
Wang, S2
Zhang, H2
Liu, QL2
Wei, Y2
Deng, W2
Wang, C2
Yang, B2
Naderi, N1
Darmishonnejad, Z1
Tavalaee, M3
Nasr-Esfahani, MH3
Gamidov, SI1
Ovchinnikov, RI1
Popova, AY1
Dong, L1
Zhang, X1
Yang, F1
Li, J1
Yu, X1
Li, Y1
Abbasi, B1
Molavi, N1
Abbasi, H1
Di Tucci, C1
Galati, G1
Mattei, G1
Bonanni, V1
Capri, O1
D'Amelio, R1
Muzii, L1
Benedetti Panici, P1
El-Maddawy, ZK1
Abd El Naby, WSH1
Prathima, P1
Pavani, R1
Sukeerthi, S1
Sainath, SB1
Zhang, GW1
Liu, W1
Shang, XJ1
Shaygannia, E1
Akhavanfarid, GR1
Rahimi, M1
Dattilo, M1
Canepa, P1
Dal Lago, A1
De Leo, C1
Gallo, M1
Rizzo, C1
Licata, E1
Anserini, P1
Rago, R1
Scaruffi, P1
Haidari, F2
Mohammadi-Asl, J2
Kavianpour, M1
Dadfar, M2
Haghighian, HK2
Niederberger, C1
Ibrahim, SF1
Osman, K1
Das, S1
Othman, AM1
Majid, NA1
Rahman, MP1
Ashour, AE1
Abdel-Hamied, HE1
Korashy, HM1
Al-Shabanah, OA1
Abd-Allah, AR1

Reviews

3 reviews available for thioctic acid and Sterility, Male

ArticleYear
The effect of alpha-lipoic acid on sperm functions in rodent models for male infertility: A systematic review.
    Life sciences, 2023, Jun-15, Volume: 323

    Topics: Animals; Antioxidants; Humans; Infertility, Male; Male; Rodentia; Semen; Spermatozoa; Thioctic Acid

2023
The role of alpha lipoic acid in female and male infertility: a systematic review.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021, Volume: 37, Issue:6

    Topics: Adult; Embryonic Development; Female; Humans; Infertility, Female; Infertility, Male; Male; Oogenesi

2021
[Advances in the studies of lipoic acid in male infertility].
    Zhonghua nan ke xue = National journal of andrology, 2017, Volume: 23, Issue:1

    Topics: Animals; Antioxidants; Asthenozoospermia; Diabetes Mellitus; Erectile Dysfunction; Humans; Infertili

2017

Trials

5 trials available for thioctic acid and Sterility, Male

ArticleYear
Effects of alpha-lipoic acid on sperm quality in patients with varicocele-related male infertility: study protocol for a randomized controlled clinical trial.
    Trials, 2022, Dec-12, Volume: 23, Issue:1

    Topics: Antioxidants; Humans; Infertility, Male; Male; Randomized Controlled Trials as Topic; Semen; Spermat

2022
Effects of alpha-lipoic acid on sperm quality in patients with varicocele-related male infertility: study protocol for a randomized controlled clinical trial.
    Trials, 2022, Dec-12, Volume: 23, Issue:1

    Topics: Antioxidants; Humans; Infertility, Male; Male; Randomized Controlled Trials as Topic; Semen; Spermat

2022
Effects of alpha-lipoic acid on sperm quality in patients with varicocele-related male infertility: study protocol for a randomized controlled clinical trial.
    Trials, 2022, Dec-12, Volume: 23, Issue:1

    Topics: Antioxidants; Humans; Infertility, Male; Male; Randomized Controlled Trials as Topic; Semen; Spermat

2022
Effects of alpha-lipoic acid on sperm quality in patients with varicocele-related male infertility: study protocol for a randomized controlled clinical trial.
    Trials, 2022, Dec-12, Volume: 23, Issue:1

    Topics: Antioxidants; Humans; Infertility, Male; Male; Randomized Controlled Trials as Topic; Semen; Spermat

2022
[Double-blind, randomized placebo-controlled study of efficiency and safety of complex acetyl-L-carnitine, L-carnitine fumarate and alpha-lipoic acid (Spermactin Forte) for treatment of male infertility].
    Urologiia (Moscow, Russia : 1999), 2019, Issue:4

    Topics: Acetylcarnitine; Adult; Carnitine; Double-Blind Method; Female; Fumarates; Humans; Infertility, Male

2019
Alpha-lipoic acid improves sperm motility in infertile men after varicocelectomy: a triple-blind randomized controlled trial.
    Reproductive biomedicine online, 2020, Volume: 41, Issue:6

    Topics: Adult; Combined Modality Therapy; Dietary Supplements; DNA Damage; DNA Fragmentation; Double-Blind M

2020
Effect of lipoic acid supplementation on gene expression and activity of glutathione S-transferase enzyme in infertile men.
    Human fertility (Cambridge, England), 2021, Volume: 24, Issue:4

    Topics: Dietary Supplements; Follicle Stimulating Hormone; Gene Expression; Glutathione Transferase; Humans;

2021
Randomized, triple-blind, placebo-controlled clinical trial examining the effects of alpha-lipoic acid supplement on the spermatogram and seminal oxidative stress in infertile men.
    Fertility and sterility, 2015, Volume: 104, Issue:2

    Topics: Adult; Dietary Supplements; Double-Blind Method; Female; Humans; Infertility, Male; Male; Oxidative

2015

Other Studies

8 other studies available for thioctic acid and Sterility, Male

ArticleYear
Effect of oral alpha-lipoic acid (ALA) on the treatment of male infertility: A protocol for systematic review and meta-analysis.
    Medicine, 2019, Volume: 98, Issue:51

    Topics: Antioxidants; Humans; Infertility, Male; Male; Meta-Analysis as Topic; Systematic Review as Topic; T

2019
Effects of ivermectin and its combination with alpha lipoic acid on expression of IGFBP-3 and HSPA1 genes and male rat fertility.
    Andrologia, 2018, Volume: 50, Issue:3

    Topics: Animals; Fertility; HSP70 Heat-Shock Proteins; Infertility, Male; Insulin-Like Growth Factor Binding

2018
α-Lipoic acid inhibits testicular and epididymal oxidative damage and improves fertility efficacy in arsenic-intoxicated rats.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:2

    Topics: Animals; Antioxidants; Arsenic Poisoning; Arsenites; Biomarkers; Epididymis; Gene Expression Regulat

2018
Alpha-Lipoic Acid improves the testicular dysfunction in rats induced by varicocele.
    Andrologia, 2018, Volume: 50, Issue:9

    Topics: Animals; Antioxidants; Chromatin; Dietary Supplements; Drug Evaluation, Preclinical; Infertility, Ma

2018
Combined treatment with myo-inositol, alpha-lipoic acid, folic acid and vitamins significantly improves sperm parameters of sub-fertile men: a multi-centric study.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:20

    Topics: Adult; Female; Folic Acid; Humans; Infertility, Male; Inositol; Male; Middle Aged; Pregnancy; Reacti

2018
Re: Randomized, Triple-Blind, Placebo-Controlled Clinical Trial Examining the Effects of Alpha-Lipoic Acid Supplement on the Spermatogram and Seminal Oxidative Stress in Infertile Men.
    The Journal of urology, 2016, Volume: 195, Issue:4 Pt 1

    Topics: Antioxidants; Dietary Supplements; Double-Blind Method; Humans; Infertility, Male; Male; Oxidative S

2016
A study of the antioxidant effect of alpha lipoic acids on sperm quality.
    Clinics (Sao Paulo, Brazil), 2008, Volume: 63, Issue:4

    Topics: Adult; Antioxidants; Comet Assay; Cryopreservation; DNA Damage; Humans; Infertility, Male; Male; Sem

2008
Alpha-lipoic acid rebalances redox and immune-testicular milieu in septic rats.
    Chemico-biological interactions, 2011, Feb-01, Volume: 189, Issue:3

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Infertility, Male;

2011