thioctic acid has been researched along with Sciatica in 3 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thioctic acid 600 mg/day appears to be at least as effective as ALC in the treatment of sciatic pain caused by a herniated disc and may be associated with an improvement in symptom scores and reduced need for analgesia." | 9.13 | Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study. ( Loiero, M; Memeo, A, 2008) |
| "Thioctic acid 600 mg/day appears to be at least as effective as ALC in the treatment of sciatic pain caused by a herniated disc and may be associated with an improvement in symptom scores and reduced need for analgesia." | 5.13 | Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study. ( Loiero, M; Memeo, A, 2008) |
| "The aim of our observational study is to compare the therapeutic efficacy of combined treatment of oxygen-ozone therapy and oral treatment with alpha-lipoic acid (ALA) + palmitoylethanolamide (PEA) and myrrh in patients with peripheral neuropathic pain (sciatica) on radicular disc conflict from disc herniation and the results obtained with oxygen-ozone treatment alone." | 4.12 | Oxygen-Ozone Therapy Associated with Alpha Lipoic Acid Plus Palmitoylethanolamide and Myrrh versus Ozone Therapy in the Combined Treatment of Sciatic Pain Due to Herniated Discs: Observational Study on 318 Patients. ( Bonetti, M; Carinci, F; Della Gatta, L; Fontana, A; Lauritano, D; Muto, M; Ottaviani, GM; Zambello, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bonetti, M | 1 |
| Lauritano, D | 1 |
| Ottaviani, GM | 1 |
| Fontana, A | 1 |
| Zambello, A | 1 |
| Della Gatta, L | 1 |
| Muto, M | 1 |
| Carinci, F | 1 |
| Horasanli, B | 1 |
| Hasturk, AE | 1 |
| Arikan, M | 1 |
| Togral, G | 1 |
| Helvacioglu, F | 1 |
| Dagdeviren, A | 1 |
| Mut, S | 1 |
| Harman, F | 1 |
| Argun, G | 1 |
| Memeo, A | 1 |
| Loiero, M | 1 |
1 trial available for thioctic acid and Sciatica
| Article | Year |
|---|---|
Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study.
Topics: Acetylcarnitine; Adult; Aged; Aged, 80 and over; Analgesics; Antioxidants; Double-Blind Method; Elec | 2008 |
2 other studies available for thioctic acid and Sciatica
| Article | Year |
|---|---|
Oxygen-Ozone Therapy Associated with Alpha Lipoic Acid Plus Palmitoylethanolamide and Myrrh versus Ozone Therapy in the Combined Treatment of Sciatic Pain Due to Herniated Discs: Observational Study on 318 Patients.
Topics: Amides; Ethanolamines; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Oxygen; Ozone; Pa | 2022 |
Comparative evaluation of the electrophysiological, functional and ultrastructural effects of alpha lipoic acid and cyanocobalamin administration in a rat model of sciatic nerve injury.
Topics: Animals; Drug Evaluation, Preclinical; Electromyography; Humans; Male; Neuroprotective Agents; Perip | 2017 |