thioctic acid has been researched along with Retinitis Pigmentosa in 2 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Retinitis Pigmentosa: Hereditary, progressive degeneration of the retina due to death of ROD PHOTORECEPTORS initially and subsequent death of CONE PHOTORECEPTORS. It is characterized by deposition of pigment in the retina.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Komeima, K | 2 |
| Rogers, BS | 2 |
| Lu, L | 1 |
| Campochiaro, PA | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| NAC Attack, A Phase III, Multicenter, Randomized, Parallel, Double Masked, Placebo-Controlled Study Evaluating the Efficacy and Safety of Oral N-Acetylcysteine in Patients With Retinitis Pigmentosa[NCT05537220] | Phase 3 | 438 participants (Anticipated) | Interventional | 2023-10-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for thioctic acid and Retinitis Pigmentosa
| Article | Year |
|---|---|
Antioxidants reduce cone cell death in a model of retinitis pigmentosa.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Cell Death; Disease Models, Animal; Electror | 2006 |
Antioxidants slow photoreceptor cell death in mouse models of retinitis pigmentosa.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Cell Death; Codon, Nonsense; Cyclic Nucleoti | 2007 |