thioctic acid has been researched along with Retinal Degeneration in 2 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dosing with LA protected photoreceptors, decreasing the numbers of TUNEL-positive photoreceptors and increasing the number of surviving photoreceptors." | 1.40 | Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina. ( Dunaief, JL; Li, Y; Song, D; Song, Y; Su, G; Wang, C; Zhao, L, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, L | 1 |
| Wang, C | 1 |
| Song, D | 1 |
| Li, Y | 1 |
| Song, Y | 1 |
| Su, G | 1 |
| Dunaief, JL | 1 |
| Kan, E | 1 |
| Alici, Ö | 1 |
| Kan, EK | 1 |
| Ayar, A | 1 |
2 other studies available for thioctic acid and Retinal Degeneration
| Article | Year |
|---|---|
Systemic administration of the antioxidant/iron chelator α-lipoic acid protects against light-induced photoreceptor degeneration in the mouse retina.
Topics: Animals; Antioxidants; Apoptosis; cis-trans-Isomerases; Electroretinography; Gene Expression; In Sit | 2014 |
Effects of alpha-lipoic acid on retinal ganglion cells, retinal thicknesses, and VEGF production in an experimental model of diabetes.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Mice, Inbred BAL | 2017 |