thioctic acid has been researched along with Pulmonary Fibrosis in 6 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 8.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "Amiodarone (AMD) is a widely used antiarrhythmic drug prescribed to treat cardiac tachyarrhythmias; however, AMD has been reported to provoke pulmonary fibrosis (PF) and hepatotoxicity." | 4.02 | The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats. ( Ibrahim Fouad, G; R Mousa, M, 2021) |
| "Silicosis is characterized by pulmonary interstitial fibrosis that arises as a result of chronic exposure to silica." | 1.62 | Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice. ( Chang, M; Li, H; Li, Y; Tao, Y; Xiong, C; Xu, G; Yan, S; Yang, X; Yao, S; Zhao, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 3 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yahyapour, R | 2 |
| Amini, P | 2 |
| Saffar, H | 1 |
| Motevaseli, E | 2 |
| Farhood, B | 1 |
| Pooladvand, V | 1 |
| Shabeeb, D | 2 |
| Musa, AE | 2 |
| Najafi, M | 2 |
| Ibrahim Fouad, G | 1 |
| R Mousa, M | 1 |
| Chang, M | 1 |
| Xu, G | 1 |
| Xiong, C | 1 |
| Yang, X | 1 |
| Yan, S | 1 |
| Tao, Y | 1 |
| Li, H | 1 |
| Li, Y | 1 |
| Yao, S | 1 |
| Zhao, Y | 1 |
| Azmoonfar, R | 1 |
| Rezaeyan, A | 1 |
| Tavassoli, A | 1 |
| Khodamoradi, E | 1 |
| Cantin, AM | 1 |
| Martel, M | 1 |
| Drouin, G | 1 |
| Paquette, B | 1 |
| Liu, R | 1 |
| Ahmed, KM | 1 |
| Nantajit, D | 1 |
| Rosenthal, FS | 1 |
| Hai, CX | 1 |
| Li, JJ | 1 |
6 other studies available for thioctic acid and Pulmonary Fibrosis
| Article | Year |
|---|---|
Protective Effect of Metformin, Resveratrol and Alpha-lipoic Acid on Radiation- Induced Pneumonitis and Fibrosis: A Histopathological Study.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Hypoglycemic Agents; Lung; Male; Metformin; | 2019 |
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats.
Topics: Alanine Transaminase; Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyt | 2021 |
Alpha-lipoic acid attenuates silica-induced pulmonary fibrosis by improving mitochondrial function via AMPK/PGC1α pathway activation in C57BL/6J mice.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Humans; Male; Metabolic Networks and Pathways; | 2021 |
Mitigation of Radiation-induced Pneumonitis and Lung Fibrosis using Alpha-lipoic Acid and Resveratrol.
Topics: Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Mice; Pulm | 2020 |
Inhibition of gelatinase B (matrix metalloproteinase-9) by dihydrolipoic acid.
Topics: Animals; Bronchoalveolar Lavage Fluid; Enzyme Inhibitors; Enzyme Precursors; Gelatinases; Humans; Ma | 2005 |
Therapeutic effects of alpha-lipoic acid on bleomycin-induced pulmonary fibrosis in rats.
Topics: Animals; Antioxidants; Bleomycin; Bronchoalveolar Lavage Fluid; Gene Expression Profiling; Glutathio | 2007 |