thioctic acid has been researched along with Primary Ovarian Insufficiency in 2 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Primary Ovarian Insufficiency: Cessation of ovarian function after MENARCHE but before the age of 40, without or with OVARIAN FOLLICLE depletion. It is characterized by the presence of OLIGOMENORRHEA or AMENORRHEA, elevated GONADOTROPINS, and low ESTRADIOL levels. It is a state of female HYPERGONADOTROPIC HYPOGONADISM. Etiologies include genetic defects, autoimmune processes, chemotherapy, radiation, and infections. The most commonly known genetic cause is the expansion of a CGG repeat to 55 to 199 copies in the 5' untranslated region in the X-linked FMR1 gene.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Premature ovarian failure is a well-known side effect of conventional, low linear energy transfer (LET) cancer radiotherapy, but little is known about the effects of high LET charged particles on the ovary." | 1.46 | Very low doses of heavy oxygen ion radiation induce premature ovarian failure. ( Luderer, U; Mishra, B; Ortiz, L; Ripperdan, R, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Özel, F | 1 |
| Kiray, M | 1 |
| Göker, A | 1 |
| Aydemir, S | 1 |
| Mıcılı, SC | 1 |
| Mishra, B | 1 |
| Ripperdan, R | 1 |
| Ortiz, L | 1 |
| Luderer, U | 1 |
2 other studies available for thioctic acid and Primary Ovarian Insufficiency
| Article | Year |
|---|---|
Protective effect of alpha lipoic acid on 4-vinylcyclohexene diepoxide induced primary ovarian failure in female rats.
Topics: Animals; Antioxidants; Cyclohexenes; Female; Ovary; Oxidative Stress; Primary Ovarian Insufficiency; | 2020 |
Very low doses of heavy oxygen ion radiation induce premature ovarian failure.
Topics: Animals; Antioxidants; Apoptosis; Astronauts; DNA Damage; Dose-Response Relationship, Radiation; Est | 2017 |