thioctic acid has been researched along with Presbycusis in 5 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Presbycusis: Gradual bilateral hearing loss associated with aging that is due to progressive degeneration of cochlear structures and central auditory pathways. Hearing loss usually begins with the high frequencies then progresses to sounds of middle and low frequencies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " α-lipoic acid was given to the mice intraperitoneally at a dosage of 50 μg/g body weight every other day." | 1.56 | Otoprotective Effects of α-lipoic Acid on A/J Mice With Age-related Hearing Loss. ( Han, F; Huang, S; Li, P; Liu, T; Lu, P; Shang, W; Sun, X; Xie, Y; Xu, A; Zhao, M; Zhou, B, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, S | 1 |
| Xu, A | 2 |
| Sun, X | 2 |
| Shang, W | 2 |
| Zhou, B | 2 |
| Xie, Y | 2 |
| Zhao, M | 1 |
| Li, P | 1 |
| Lu, P | 1 |
| Liu, T | 2 |
| Han, F | 2 |
| Wang, Y | 1 |
| Xu, X | 1 |
| Takumida, M | 1 |
| Anniko, M | 1 |
| Polanski, JF | 1 |
| Cruz, OL | 1 |
| Seidman, MD | 1 |
| Khan, MJ | 1 |
| Bai, U | 1 |
| Shirwany, N | 1 |
| Quirk, WS | 1 |
1 trial available for thioctic acid and Presbycusis
| Article | Year |
|---|---|
Evaluation of antioxidant treatment in presbyacusis: prospective, placebo-controlled, double-blind, randomised trial.
Topics: Aged; Aged, 80 and over; Antioxidants; Ascorbic Acid; Auditory Threshold; Double-Blind Method; Femal | 2013 |
4 other studies available for thioctic acid and Presbycusis
| Article | Year |
|---|---|
Otoprotective Effects of α-lipoic Acid on A/J Mice With Age-related Hearing Loss.
Topics: Animals; Cochlea; Evoked Potentials, Auditory, Brain Stem; Mice; Presbycusis; Spiral Ganglion; Thioc | 2020 |
ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.
Topics: Activating Transcription Factor 6; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Cas | 2020 |
Radical scavengers for elderly patients with age-related hearing loss.
Topics: Aged; Aged, 80 and over; Alanine; Ascorbic Acid; Audiometry, Pure-Tone; Drug Therapy, Combination; E | 2009 |
Biologic activity of mitochondrial metabolites on aging and age-related hearing loss.
Topics: Acetylcarnitine; Aging; Animals; Auditory Threshold; Biological Transport; Cell Membrane; Cochlear N | 2000 |