thioctic acid has been researched along with Necrosis in 13 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vitamin C (ascorbate) is toxic to tumour cells, and has been suggested as an adjuvant cancer treatment." | 1.31 | Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours. ( Casciari, JJ; Jackson, JA; Meng, XL; Riordan, HD; Riordan, NH; Schmidt, TL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (38.46) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Tcheng, JE | 1 |
| Gibson, M | 1 |
| Krucoff, MW | 1 |
| Patel, MR | 1 |
| Ajit, M | 1 |
| Hiremath, J | 1 |
| Ponde, C | 1 |
| Ramsaran, E | 1 |
| Clark, G | 1 |
| Lader, AS | 1 |
| Beeuwkes, R | 1 |
| Fontani, F | 1 |
| Marcucci, G | 1 |
| Iantomasi, T | 1 |
| Brandi, ML | 1 |
| Vincenzini, MT | 1 |
| Çakır, T | 1 |
| Baştürk, A | 1 |
| Polat, C | 1 |
| Aslaner, A | 1 |
| Durgut, H | 1 |
| Şehirli, AÖ | 1 |
| Gül, M | 1 |
| Öğünç, AV | 1 |
| Gül, S | 1 |
| Sabuncuoglu, MZ | 1 |
| Oruç, MT | 1 |
| Lee, YM | 1 |
| Bae, SY | 1 |
| Won, NH | 1 |
| Pyo, HJ | 1 |
| Kwon, YJ | 1 |
| Selvakumar, E | 1 |
| Prahalathan, C | 1 |
| Varalakshmi, P | 1 |
| Kumarasamy, P | 1 |
| Saravanan, R | 1 |
| Hnia, K | 1 |
| Hugon, G | 1 |
| Rivier, F | 1 |
| Masmoudi, A | 1 |
| Mercier, J | 1 |
| Mornet, D | 1 |
| Duenschede, F | 1 |
| Erbes, K | 1 |
| Riegler, N | 1 |
| Ewald, P | 1 |
| Kircher, A | 1 |
| Westermann, S | 1 |
| Schad, A | 1 |
| Miesmer, I | 1 |
| Albrecht-Schöck, S | 1 |
| Gockel, I | 1 |
| Kiemer, AK | 1 |
| Junginger, T | 1 |
| Casciari, JJ | 1 |
| Riordan, NH | 1 |
| Schmidt, TL | 1 |
| Meng, XL | 1 |
| Jackson, JA | 1 |
| Riordan, HD | 1 |
| Thölen, H | 1 |
| Colombi, A | 1 |
| Duckert, F | 1 |
| Huber, F | 1 |
| Müller, HR | 1 |
| Bigler, F | 1 |
| Sawai, Y | 2 |
| Chinzei, H | 1 |
| Kawamura, Y | 2 |
| Okonogi, T | 2 |
| Gazzard, BG | 1 |
| Hughes, RD | 1 |
| Portmann, B | 1 |
| Dordoni, B | 1 |
| Williams, R | 1 |
| Clayton, BE | 1 |
| Dobbs, RH | 1 |
| Patrick, AD | 1 |
| Fukuyama, T | 1 |
| Ebisawa, I | 1 |
1 trial available for thioctic acid and Necrosis
| Article | Year |
|---|---|
SUPPORT-1 (Subjects Undergoing PCI and Perioperative Reperfusion Treatment): A Prospective, Randomized Trial of CMX-2043 in Patients Undergoing Elective Percutaneous Coronary Intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; Cardiovascular Agents; Coronary Artery Disease; Cr | 2020 |
12 other studies available for thioctic acid and Necrosis
| Article | Year |
|---|---|
Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1/2 signalling.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Apoptosis; Bone Disease | 2015 |
Does alfa lipoic acid prevent liver from methotrexate induced oxidative injury in rats?
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Chemical and Drug | 2015 |
Alpha-lipoic acid attenuates cisplatin-induced tubulointerstitial injuries through inhibition of mitochondrial bax translocation in rats.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blood Urea Nitrogen; Caspase 3; Caspas | 2009 |
Modification of cyclophosphamide-induced clastogenesis and apoptosis in rats by alpha-lipoic acid.
Topics: Animals; Apoptosis; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Mammalian; Cyclophospham | 2006 |
Modulation of p38 mitogen-activated protein kinase cascade and metalloproteinase activity in diaphragm muscle in response to free radical scavenger administration in dystrophin-deficient Mdx mice.
Topics: Animals; Apoptosis; Calcium; Carnitine; Creatine Kinase; Diaphragm; Dystroglycans; Dystrophin; Free | 2007 |
Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Caspase 3; Caspase 9; | 2007 |
Cytotoxicity of ascorbate, lipoic acid, and other antioxidants in hollow fibre in vitro tumours.
Topics: Antioxidants; Apoptosis; Ascorbic Acid; Carcinoma; Colonic Neoplasms; Dose-Response Relationship, Dr | 2001 |
Effects of a treatment with coenzyme A, alpha-lipoic acid, diphosphopyridine nucleotide and cocarboxylase on endogenous hepatic coma.
Topics: Adolescent; Adult; Aged; Ammonia; Bilirubin; Biopsy; Blood Coagulation Factors; Blood Coagulation Te | 1967 |
Studies on the improvement of treatment of Habu (Trimeresurus flavoviridis) bites. 9. Studies on the immunogenicity of the purified Habu venom toxoid by alcohol precipitation.
Topics: Animals; Antibody Formation; Chemical Precipitation; Ethanol; Formaldehyde; Guinea Pigs; Hemorrhage; | 1972 |
Protection of rats against the hepatotoxic effect of paracetamol.
Topics: Acetaminophen; Administration, Oral; Animals; Cysteamine; Cytochrome P-450 Enzyme System; Drug Inter | 1974 |
Leigh's subacute necrotizing encephalopathy: clinical and biochemical study, with special reference to therapy with lipoate.
Topics: Blood Chemical Analysis; Brain Diseases; Brain Stem; Child; Child, Preschool; Clinical Enzyme Tests; | 1967 |
Studies on the improvement of treatment on habu (Trimeresurus flavoviridis) bites. 8. A field trial of the prophylactic inoculation of the habu venom toxoid.
Topics: Antibodies; Humans; Immunization; Necrosis; Neutralization Tests; Prognosis; Snake Bites; Thioctic A | 1969 |