thioctic acid has been researched along with Migraine Disorders in 5 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nutraceuticals like alpha-lipoic acid (ALA) may have potential benefits as prophylactic agents for adolescent migraine, with fewer adverse events than existing medications." | 3.30 | Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial. ( Jena, M; Maiti, R; Mishra, BR; Puliappadamb, HM; Satpathy, AK, 2023) |
| "In total, 92 women with episodic migraine participated in the study." | 3.01 | The efficacy of alpha-lipoic acid in improving oxidative, inflammatory, and mood status in women with episodic migraine in a randomised, double-blind, placebo-controlled clinical trial. ( Alavi Naeini, A; Askari, G; Heidari, Z; Khorvash, F; Rezaei Kelishadi, M, 2021) |
| "Five Belgian centers recruited 54 migraineurs (43 migraine without aura, 11 with aura; mean age 38 +/- 8 years; 7 males)." | 2.73 | A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis. ( Ambrosini, A; Jacquy, J; Laloux, P; Magis, D; Sándor, P; Schoenen, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelishadi, MR | 1 |
| Naeini, AA | 1 |
| Khorvash, F | 2 |
| Askari, G | 2 |
| Heidari, Z | 2 |
| Puliappadamb, HM | 1 |
| Satpathy, AK | 1 |
| Mishra, BR | 1 |
| Maiti, R | 1 |
| Jena, M | 1 |
| Rezaei Kelishadi, M | 1 |
| Alavi Naeini, A | 1 |
| Brenner, SR | 1 |
| Magis, D | 1 |
| Ambrosini, A | 1 |
| Sándor, P | 1 |
| Jacquy, J | 1 |
| Laloux, P | 1 |
| Schoenen, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-blinded, Placebo-controlled Trial of Idebenone in the Prevention of Episodic Migraine[NCT04151472] | Phase 3 | 180 participants (Anticipated) | Interventional | 2021-12-08 | Recruiting | ||
| Evaluation of Efficacy and Safety of add-on Alpha-lipoic Acid on Migraine Prophylaxis in Adolescent Population: A Randomized Controlled Trial[NCT04064814] | Phase 4 | 60 participants (Actual) | Interventional | 2019-09-14 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for thioctic acid and Migraine Disorders
| Article | Year |
|---|---|
The beneficial effect of Alpha-lipoic acid supplementation as a potential adjunct treatment in episodic migraines.
Topics: Adult; Dietary Supplements; Double-Blind Method; Female; Humans; Iran; Lactic Acid; Migraine Disorde | 2022 |
Evaluation of Safety and Efficacy of Add-on Alpha-Lipoic Acid on Migraine Prophylaxis in an Adolescent Population: A Randomized Controlled Trial.
Topics: Adolescent; Analgesics; Calcitonin Gene-Related Peptide; Child; Double-Blind Method; Flunarizine; Hu | 2023 |
The efficacy of alpha-lipoic acid in improving oxidative, inflammatory, and mood status in women with episodic migraine in a randomised, double-blind, placebo-controlled clinical trial.
Topics: Antioxidants; Biomarkers; C-Reactive Protein; Dietary Supplements; Double-Blind Method; Female; Huma | 2021 |
A randomized double-blind placebo-controlled trial of thioctic acid in migraine prophylaxis.
Topics: Adult; Belgium; Double-Blind Method; Energy Metabolism; Female; Humans; Male; Middle Aged; Migraine | 2007 |
1 other study available for thioctic acid and Migraine Disorders
| Article | Year |
|---|---|
Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs.
Topics: Brain Diseases, Metabolic; Chronic Disease; Disease Progression; DNA, Mitochondrial; Genetic Predisp | 2010 |