thioctic acid has been researched along with Macular Degeneration in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study evaluates the toxic effects of chrysene (a component from cigarette smoke) on Müller cells (MIO-M1) in vitro and investigates whether the inhibitor lipoic acid can reverse the chrysene-induced toxic effects." | 1.39 | Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro. ( Gupta, N; Kenney, MC; Kuppermann, BD; Limb, GA; Luczy-Bachman, G; Mansoor, S, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lewis Luján, LM | 1 |
| McCarty, MF | 1 |
| Di Nicolantonio, JJ | 1 |
| Gálvez Ruiz, JC | 1 |
| Rosas-Burgos, EC | 1 |
| Plascencia-Jatomea, M | 1 |
| Iloki Assanga, SB | 1 |
| Tao, Y | 1 |
| Jiang, P | 1 |
| Wei, Y | 1 |
| Wang, P | 1 |
| Sun, X | 1 |
| Wang, H | 1 |
| Sun, YD | 1 |
| Dong, YD | 1 |
| Fan, R | 1 |
| Zhai, LL | 1 |
| Bai, YL | 1 |
| Jia, LH | 1 |
| Mansoor, S | 1 |
| Gupta, N | 1 |
| Luczy-Bachman, G | 1 |
| Limb, GA | 1 |
| Kuppermann, BD | 1 |
| Kenney, MC | 1 |
1 review available for thioctic acid and Macular Degeneration
| Article | Year |
|---|---|
Nutraceuticals/Drugs Promoting Mitophagy and Mitochondrial Biogenesis May Combat the Mitochondrial Dysfunction Driving Progression of Dry Age-Related Macular Degeneration.
Topics: AMP-Activated Protein Kinases; Berberine; Dietary Supplements; DNA, Mitochondrial; Glucosamine; Huma | 2022 |
2 trials available for thioctic acid and Macular Degeneration
| Article | Year |
|---|---|
α-Lipoic Acid Treatment Improves Vision-Related Quality of Life in Patients with Dry Age-Related Macular Degeneration.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Contrast Sensitivity; Demography; Humans; Macular Deg | 2016 |
Effect of (R)-α-lipoic acid supplementation on serum lipids and antioxidative ability in patients with age-related macular degeneration.
Topics: Administration, Oral; Aged; Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Dietary Supplements; F | 2012 |
1 other study available for thioctic acid and Macular Degeneration
| Article | Year |
|---|---|
Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro.
Topics: Adenosine Triphosphate; Caspases; Cell Line; Cell Survival; Chrysenes; Humans; L-Lactate Dehydrogena | 2013 |