thioctic acid has been researched along with Lung Neoplasms in 14 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hydroxycitrate, spermidine, and alpha-lipoic acid, CRMs that target different metabolic enzymes, administered by aerosol, strongly reduced implantation of intravenously injected B16 melanoma cells without overt signs of toxicity, such as weight loss and changes in lung structure." | 3.91 | Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases. ( Balsari, A; Bianchi, F; Le Noci, V; Sfondrini, L; Sommariva, M; Tagliabue, E; Triulzi, T, 2019) |
| "In addition, DTX, a model drug for breast cancer treatment, was loaded (76." | 1.62 | A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases. ( Ji, J; Kong, X; Liu, D; Qiu, N; Xi, Y; Yang, X; Ye, L; Zhai, G; Zhang, J; Zhang, Y, 2021) |
| "Lung cancer is the leading cause of cancer-related death, and there remains a need for novel therapies for this malignancy." | 1.56 | Alpha-lipoic acid inhibits lung cancer growth via mTOR-mediated autophagy inhibition. ( Cao, X; Cheng, H; Ding, Z; Kong, Q; Liu, L; Peng, P; Qi, T; Zhang, X, 2020) |
| "Chemotherapeutic failure and metastasis are the main causes of high mortality rate in lung cancer." | 1.43 | α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin β1/β3 downregulation. ( Chanvorachote, P; Chaotham, C; Puchsaka, P, 2016) |
| "8) suggesting that the camptothecin regimen was synergistic and that the addition of sodium-R-alpha lipoate was important for reducing the camptothecin dose and potential for adverse effects." | 1.40 | Selective cytotoxicity and combined effects of camptothecin or paclitaxel with sodium-R-alpha lipoate on A549 human non-small cell lung cancer cells. ( Gao, D; Ibrahim, S; Sinko, PJ, 2014) |
| "Similar effects were observed in PC3 prostate cancer and Ramos B-cell lymphoma cell lines." | 1.33 | Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines. ( Biaglow, JE; Chawannakul, D; Hacia, JG; Ho, VV; Karaman, MW; Lecane, P; Lepp, C; Magda, D; Mesfin, M; Miles, D; Miller, RA; Nagpal, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Qiu, N | 1 |
| Yang, X | 1 |
| Zhang, Y | 2 |
| Zhang, J | 1 |
| Ji, J | 1 |
| Kong, X | 1 |
| Xi, Y | 1 |
| Liu, D | 1 |
| Ye, L | 1 |
| Zhai, G | 1 |
| Fang, H | 1 |
| Zhao, X | 1 |
| Gu, X | 1 |
| Sun, H | 1 |
| Cheng, R | 1 |
| Zhong, Z | 1 |
| Deng, C | 1 |
| Peng, P | 1 |
| Zhang, X | 1 |
| Qi, T | 1 |
| Cheng, H | 1 |
| Kong, Q | 1 |
| Liu, L | 1 |
| Cao, X | 1 |
| Ding, Z | 2 |
| Yue, L | 1 |
| Ren, Y | 1 |
| Yue, Q | 1 |
| Wang, K | 1 |
| Zheng, T | 1 |
| Chen, G | 1 |
| Chen, X | 1 |
| Li, M | 1 |
| Fan, L | 1 |
| Phiboonchaiyanan, PP | 1 |
| Chanvorachote, P | 3 |
| Le Noci, V | 1 |
| Sommariva, M | 1 |
| Bianchi, F | 1 |
| Triulzi, T | 1 |
| Tagliabue, E | 1 |
| Balsari, A | 1 |
| Sfondrini, L | 1 |
| Michikoshi, H | 1 |
| Nakamura, T | 1 |
| Sakai, K | 1 |
| Suzuki, Y | 1 |
| Adachi, E | 1 |
| Matsugo, S | 1 |
| Matsumoto, K | 1 |
| Inui, T | 1 |
| Kuchiike, D | 1 |
| Kubo, K | 1 |
| Mette, M | 1 |
| Uto, Y | 1 |
| Hori, H | 1 |
| Sakamoto, N | 1 |
| Ibrahim, S | 1 |
| Gao, D | 1 |
| Sinko, PJ | 1 |
| Puchsaka, P | 1 |
| Chaotham, C | 1 |
| Gu, F | 1 |
| Hu, C | 1 |
| Tai, Z | 1 |
| Yao, C | 1 |
| Tian, J | 1 |
| Zhang, L | 1 |
| Xia, Q | 1 |
| Gong, C | 1 |
| Gao, Y | 1 |
| Gao, S | 1 |
| Choi, SY | 1 |
| Yu, JH | 1 |
| Kim, H | 1 |
| Magda, D | 1 |
| Lecane, P | 1 |
| Miller, RA | 1 |
| Lepp, C | 1 |
| Miles, D | 1 |
| Mesfin, M | 1 |
| Biaglow, JE | 1 |
| Ho, VV | 1 |
| Chawannakul, D | 1 |
| Nagpal, S | 1 |
| Karaman, MW | 1 |
| Hacia, JG | 1 |
| Moungjaroen, J | 1 |
| Nimmannit, U | 1 |
| Callery, PS | 1 |
| Wang, L | 1 |
| Azad, N | 1 |
| Lipipun, V | 1 |
| Rojanasakul, Y | 1 |
14 other studies available for thioctic acid and Lung Neoplasms
| Article | Year |
|---|---|
A molybdenum oxide-based degradable nanosheet for combined chemo-photothermal therapy to improve tumor immunosuppression and suppress distant tumors and lung metastases.
Topics: Animals; Biocompatible Materials; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Doxorubicin; Fe | 2021 |
CD44-Targeted Multifunctional Nanomedicines Based on a Single-Component Hyaluronic Acid Conjugate with All-Natural Precursors: Construction and Treatment of Metastatic Breast Tumors
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Docetaxel; Drug Carriers; Drug Delivery Systems; F | 2020 |
Alpha-lipoic acid inhibits lung cancer growth via mTOR-mediated autophagy inhibition.
Topics: A549 Cells; Adenocarcinoma of Lung; Administration, Oral; Animals; Antineoplastic Agents; Autophagy; | 2020 |
Topics: Apoptosis; Humans; Lung Neoplasms; NF-E2-Related Factor 2; Pyruvate Dehydrogenase Acetyl-Transferrin | 2021 |
Suppression of a cancer stem-like phenotype mediated by alpha-lipoic acid in human lung cancer cells through down-regulation of β-catenin and Oct-4.
Topics: Antioxidants; beta Catenin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Su | 2017 |
Local Administration of Caloric Restriction Mimetics to Promote the Immune Control of Lung Metastases.
Topics: Animals; Antigens, CD; Caloric Restriction; Citrates; Dendritic Cells; Integrin alpha Chains; Interl | 2019 |
α-Lipoic acid-induced inhibition of proliferation and met phosphorylation in human non-small cell lung cancer cells.
Topics: Antioxidants; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; ErbB | 2013 |
Clinical experience of integrative cancer immunotherapy with GcMAF.
Topics: Aged; Ascorbic Acid; Bone Neoplasms; Cell- and Tissue-Based Therapy; Combined Modality Therapy; Fema | 2013 |
Selective cytotoxicity and combined effects of camptothecin or paclitaxel with sodium-R-alpha lipoate on A549 human non-small cell lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Epithe | 2014 |
α-Lipoic acid sensitizes lung cancer cells to chemotherapeutic agents and anoikis via integrin β1/β3 downregulation.
Topics: Anoikis; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Down | 2016 |
Tumour microenvironment-responsive lipoic acid nanoparticles for targeted delivery of docetaxel to lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Proliferation; Docetaxel; Drug Delivery Systems; Dr | 2016 |
Mechanism of alpha-lipoic acid-induced apoptosis of lung cancer cells.
Topics: Antioxidants; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Calcium; Caspases; Cell Line, | 2009 |
Motexafin gadolinium disrupts zinc metabolism in human cancer cell lines.
Topics: Acetates; Antineoplastic Agents; Cadmium; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Gene | 2005 |
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation.
Topics: Apoptosis; Blotting, Western; Caspases; Cell Line, Tumor; Down-Regulation; Enzyme Activation; Epithe | 2006 |