thioctic acid has been researched along with Liver Neoplasms in 22 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatocellular carcinoma is the most frequent primary liver cancer worldwide." | 1.48 | Integrated transcriptomic and proteomic analyses reveal ɑ-lipoic acid-regulated cell proliferation via Grb2-mediated signalling in hepatic cancer cells. ( Lu, J; Sun, X; Wang, R; Wang, X; Wen, Y; Xu, J; Yang, L; Zhang, M, 2018) |
| "Furthermore, in human liver cancer tissue samples, increased NRF2 expression correlated with metastasis." | 1.43 | NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis. ( Fang, F; Huang, Y; Li, W; Liao, Q; Liao, X; Liu, X; Long, M; Ouyang, Q; Rojo de la Vega, M; Tang, Z; Tong, Q; Wang, H; Wang, X; Wang, Y; Yu, S; Zhang, DD; Zhang, L; Zhang, R; Zheng, H; Zheng, Y, 2016) |
| "Fatty liver is common in obese subjects with insulin resistance." | 1.35 | Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways. ( Choi, HS; Hwang, JS; Jang, BK; Kim, HS; Kim, JB; Kim, MO; Kim, YD; Koh, EH; Lee, IK; Lee, KU; Min, AK; Park, HS; Park, JY; Park, KG; Yoon, TS, 2008) |
| "However, identical exposure of HepG2 hepatoma cells produced no inhibition of these cytokine responses." | 1.35 | Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption. ( Halvorsen, SW; Monroe, RK, 2009) |
| "Three additional pancreatic cancer case studies are presented in this article." | 1.35 | Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases. ( Berkson, AJ; Berkson, BM; Rubin, DM, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Tuo, D | 1 |
| Guo, G | 1 |
| Gan, J | 1 |
| Yang, L | 1 |
| Wang, X | 2 |
| Xu, J | 1 |
| Wen, Y | 1 |
| Zhang, M | 1 |
| Lu, J | 1 |
| Wang, R | 1 |
| Sun, X | 1 |
| Inui, T | 1 |
| Kuchiike, D | 1 |
| Kubo, K | 1 |
| Mette, M | 1 |
| Uto, Y | 1 |
| Hori, H | 1 |
| Sakamoto, N | 1 |
| Giordano, E | 1 |
| Davalos, A | 1 |
| Nicod, N | 1 |
| Visioli, F | 1 |
| Zhu, H | 1 |
| Zhang, S | 1 |
| Ling, Y | 1 |
| Meng, G | 1 |
| Yang, Y | 1 |
| Zhang, W | 1 |
| Roberts, JL | 1 |
| He, B | 1 |
| Erickson, A | 1 |
| Moreau, R | 1 |
| Wang, H | 1 |
| Liu, X | 1 |
| Long, M | 1 |
| Huang, Y | 1 |
| Zhang, L | 1 |
| Zhang, R | 1 |
| Zheng, Y | 1 |
| Liao, X | 1 |
| Wang, Y | 1 |
| Liao, Q | 1 |
| Li, W | 1 |
| Tang, Z | 1 |
| Tong, Q | 1 |
| Fang, F | 1 |
| Rojo de la Vega, M | 1 |
| Ouyang, Q | 1 |
| Zhang, DD | 1 |
| Yu, S | 1 |
| Zheng, H | 1 |
| Ikuta, N | 1 |
| Chikamoto, K | 1 |
| Asano, Y | 1 |
| Yasui, Y | 1 |
| Yokokawa, H | 1 |
| Terao, K | 1 |
| Rimbach, G | 1 |
| Matsugo, S | 1 |
| Park, KG | 1 |
| Min, AK | 1 |
| Koh, EH | 1 |
| Kim, HS | 1 |
| Kim, MO | 1 |
| Park, HS | 1 |
| Kim, YD | 1 |
| Yoon, TS | 1 |
| Jang, BK | 1 |
| Hwang, JS | 1 |
| Kim, JB | 1 |
| Choi, HS | 1 |
| Park, JY | 1 |
| Lee, IK | 1 |
| Lee, KU | 1 |
| Walden, HR | 1 |
| Kirby, JA | 1 |
| Yeaman, SJ | 1 |
| Gray, J | 1 |
| Jones, DE | 1 |
| Palmer, JM | 1 |
| Monroe, RK | 1 |
| Halvorsen, SW | 1 |
| Berkson, BM | 2 |
| Rubin, DM | 2 |
| Berkson, AJ | 2 |
| Filatova, NA | 1 |
| Kirpichnikova, KM | 1 |
| Aksenov, ND | 1 |
| Vakhromova, EA | 1 |
| Gamaleĭ, IA | 1 |
| Guerriero, E | 1 |
| Sorice, A | 1 |
| Capone, F | 1 |
| Costantini, S | 1 |
| Palladino, P | 1 |
| D'ischia, M | 1 |
| Castello, G | 1 |
| LEE, SJ | 1 |
| KAO, MS | 1 |
| HUANG, PC | 1 |
| SUNG, JL | 1 |
| MOORE, EC | 1 |
| REICHARD, P | 1 |
| Simbula, G | 2 |
| Columbano, A | 2 |
| Ledda-Columbano, GM | 2 |
| Sanna, L | 1 |
| Deidda, M | 1 |
| Diana, A | 1 |
| Pibiri, M | 2 |
| Perra, A | 1 |
| Sulas, P | 1 |
| Shi, DY | 1 |
| Liu, HL | 1 |
| Stern, JS | 1 |
| Yu, PZ | 1 |
| Liu, SL | 1 |
| Schultz, A | 1 |
| Sasaki, M | 1 |
| Natelson, S | 1 |
| Iasinovskiĭ, MA | 1 |
| Terletskaia, TM | 1 |
| Bondarchuk, AF | 1 |
22 other studies available for thioctic acid and Liver Neoplasms
| Article | Year |
|---|---|
Aberrant expression of cuproptosis‑related gene LIPT1 is associated with metabolic dysregulation of fatty acid and prognosis in hepatocellular carcinoma.
Topics: Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Copper; Fa | 2023 |
Integrated transcriptomic and proteomic analyses reveal ɑ-lipoic acid-regulated cell proliferation via Grb2-mediated signalling in hepatic cancer cells.
Topics: Carcinoma, Hepatocellular; Cell Proliferation; Disease-Free Survival; Female; Gene Expression Regula | 2018 |
Clinical experience of integrative cancer immunotherapy with GcMAF.
Topics: Aged; Ascorbic Acid; Bone Neoplasms; Cell- and Tissue-Based Therapy; Combined Modality Therapy; Fema | 2013 |
Hydroxytyrosol attenuates tunicamycin-induced endoplasmic reticulum stress in human hepatocarcinoma cells.
Topics: Antioxidants; Carcinoma, Hepatocellular; Endoplasmic Reticulum Stress; Glutathione; Hep G2 Cells; He | 2014 |
pH-responsive hybrid quantum dots for targeting hypoxic tumor siRNA delivery.
Topics: Animals; Cadmium Compounds; Cell Hypoxia; Cell Survival; Deoxyglucose; Gene Expression Regulation, N | 2015 |
Improvement of mTORC1-driven overproduction of apoB-containing triacylglyceride-rich lipoproteins by short-chain fatty acids, 4-phenylbutyric acid and (R)-α-lipoic acid, in human hepatocellular carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Apolipoprotein B-100; Carcinoma, Hepatocellular; Carrier Prote | 2016 |
NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis.
Topics: Adamantane; Animals; Antioxidants; Biomarkers, Tumor; Cell Line, Tumor; Dipeptides; Dipeptidyl-Pepti | 2016 |
Time Course Effect of R-Alpha-Lipoic Acid on Cellular Metabolomics in Cultured Hepatoma Cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Glucose; Humans; Liver Neop | 2017 |
Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways.
Topics: AMP-Activated Protein Kinases; Carcinoma, Hepatocellular; Cell Line, Tumor; Enzyme Activation; Fatty | 2008 |
Xenobiotic incorporation into pyruvate dehydrogenase complex can occur via the exogenous lipoylation pathway.
Topics: Adenosine Triphosphate; Animals; Autoimmunity; Caproates; Carcinoma, Hepatocellular; Cell Line; Cell | 2008 |
Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruption.
Topics: 2,6-Dichloroindophenol; Antioxidants; Cadmium Chloride; Carcinoma, Hepatocellular; Cell Line, Tumor; | 2009 |
Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Disease-Fre | 2009 |
[Decrease in tumorigenic activity of murine hepatoma cells after treatment with antioxidants and melatonin].
Topics: Acetylcysteine; Animals; Antioxidants; Carcinoma, Hepatocellular; Cell Cycle; Flow Cytometry; Humans | 2011 |
Effects of lipoic acid, caffeic acid and a synthesized lipoyl-caffeic conjugate on human hepatoma cell lines.
Topics: Antineoplastic Agents; Antioxidants; Caffeic Acids; Carcinoma, Hepatocellular; Cell Proliferation; C | 2011 |
THE EFFECT OF THIOCTIC ACID ON BLOOD ALPHA-KETO ACID LEVELS IN LIVER DISEASES.
Topics: Blood Chemical Analysis; Carcinoma, Hepatocellular; Chromatography; Hepatic Encephalopathy; Hepatiti | 1963 |
ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES. VI. THE CYTIDINE DIPHOSPHATE REDUCTASE SYSTEM FROM NOVIKOFF HEPATOMA.
Topics: Adenosine Triphosphate; Animals; Bacterial Proteins; Carcinoma, Hepatocellular; Cytosine Nucleotides | 1964 |
The long-term survival of a patient with pancreatic cancer with metastases to the liver after treatment with the intravenous alpha-lipoic acid/low-dose naltrexone protocol.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Disease-Free Surviva | 2006 |
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells.
Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Ascorbic Acid; bcl-2-Associated X Protein; Carcino | 2007 |
Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model.
Topics: Animals; Antioxidants; Cell Death; Choline Deficiency; Lipid Peroxidation; Liver Neoplasms; Precance | 2008 |
Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Enzyme Acti | 2008 |
Comparison of the ribonucleotide with the canavanine reductase system.
Topics: Amino Acid Oxidoreductases; Animals; Canavanine; Carcinoma, Hepatocellular; Cell Division; Cells, Cu | 1974 |
[Use of lipoic acid in complex therapy of patients with liver diseases].
Topics: Adult; Amides; Female; Humans; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Thioctic Acid | 1969 |