Page last updated: 2024-10-19

thioctic acid and Liver Dysfunction

thioctic acid has been researched along with Liver Dysfunction in 59 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-199048 (81.36)18.7374
1990's2 (3.39)18.2507
2000's7 (11.86)29.6817
2010's2 (3.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ren, Y1
Wang, LH1
Deng, FS1
Li, JS1
Jiang, L1
Shanmugarajan, TS1
Sivaraman, D1
Somasundaram, I1
Arunsundar, M1
Krishnakumar, E1
Balaji, R1
Ravichandiran, V1
Masuda, T1
Iwashita, Y1
Hagiwara, S1
Ohta, M1
Inomata, M1
Noguchi, T1
Kitano, S1
BUTTURINI, U1
MAINOLI, S1
PICCINELLI, O1
EGER, W1
ROTH, H1
CRUCHAUD, A1
BARBERA, G1
PERAZZO, E1
CALUZZI, F1
CORTESE, LF1
PASQUALINO, A1
MORGANO, G2
FAZIO, B2
BALESTRERI, R2
HASHIMOTO, S2
HATAKEYAMA, T1
PACE, O1
KRUESKEMPER, HL1
KORUS, W1
SQUADRITO, G1
CERUSO, D1
SACCA, A1
BREUER, H1
SCHOENFELDER, M1
SCHREIBER, HW1
BURGMANN, W1
CASTELLANI, L1
TAKAHASHI, K1
CAZZOLA, D1
CHOI, KW1
da COSTA, S1
da SILVA, J1
MALDONADO, FE1
DITTRICH, H1
SEIFERT, E1
MURABAYASHI, A1
YAMADA, M1
KONO, H1
RAUSCH, F1
PAGLIARO, L1
CATANIA, A1
PETZOLD, H1
RITSCHEL, W1
PUPITA, F1
PUGGIONI, G1
Suntres, ZE1
Selvakumar, E1
Prahalathan, C1
Mythili, Y1
Varalakshmi, P1
Duenschede, F1
Westermann, S1
Miesner, I1
Albrecht-Schöck, S1
Kneist, W1
Korenkov, M1
Schad, A1
Dutkowski, P1
Kiemer, AK1
Junginger, T1
Abdel-Zaher, AO1
Abdel-Hady, RH1
Mahmoud, MM1
Farrag, MM1
Anandakumar, PP1
Malarkodi, SP1
Sivaprasad, TR1
Saravanan, GD1
Huslarová, A1
Fric, P1
Bustamante, J1
Lodge, JK1
Marcocci, L1
Tritschler, HJ1
Packer, L1
Rihn, BH1
Baker, H1
Deangelis, B1
Baker, ER1
Hutner, SH1
Bilska, A1
Włodek, L1
Obeid, H1
Romanov, VS2
Jenner, RE1
Howard, ER1
Clarke, MB1
Barrett, JJ1
Berkson, BM1
Caban, M1
Möller, E2
Schmitt, R1
Jezek, P1
Horecká, J1
Caroli, J1
Benhamou, JP1
Debray, C1
Gaultier, M1
Leger, L1
Bani, G1
Ilinich, VK1
Plastun, FF1
Loginov, AS1
Isakova, ZS1
Bakumenko, MS1
Iutanova, II1
Dabski, H2
Iasinovskiĭ, MA1
Terletskaia, TM1
Bondarchuk, AF1
Ivkov, VG1
Brzeski, Z1
Brinkmann, W1
Klein, B1
Kobayashi, T1

Reviews

4 reviews available for thioctic acid and Liver Dysfunction

ArticleYear
Alpha-lipoic acid in liver metabolism and disease.
    Free radical biology & medicine, 1998, Volume: 24, Issue:6

    Topics: Animals; Humans; Liver; Liver Diseases; Thioctic Acid

1998
[Biologic properties of lipoic acid].
    Postepy higieny i medycyny doswiadczalnej, 2002, Volume: 56, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Aging; Animals; Antioxidants; Cataract; Decarboxylation; Diabeti

2002
[Treatment of acute hepatic insufficiency (a survey of the literature)].
    Voenno-meditsinskii zhurnal, 1972, Volume: 12

    Topics: Acute Disease; Adenosine Triphosphate; Arginine; Chemical and Drug Induced Liver Injury; Exchange Tr

1972
[Clinical use of thioctic acid].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Sep-30, Volume: 24, Issue:39

    Topics: Animals; Brain Chemistry; Diabetes Mellitus; Diuretics; Glycogen; Hepatolenticular Degeneration; Hum

1969

Trials

2 trials available for thioctic acid and Liver Dysfunction

ArticleYear
[A contribution to the treatment of chronic liver diseases (author's transl)].
    Medizinische Klinik, 1976, Oct-22, Volume: 71, Issue:43

    Topics: Administration, Oral; Adult; Alcoholism; Chemical and Drug Induced Liver Injury; Chronic Disease; Cl

1976
[Is the rebound effect in liver diseases following glucocorticoid therapy avoidable by using alpha-lipoic acid?].
    Therapie der Gegenwart, 1971, Volume: 110, Issue:12

    Topics: Chronic Disease; Drug Interactions; Humans; Liver Diseases; Paramethasone; Substance Withdrawal Synd

1971

Other Studies

53 other studies available for thioctic acid and Liver Dysfunction

ArticleYear
Protective effect and mechanism of alpha-lipoic acid on partial hepatic ischemia-reperfusion injury in adult male rats.
    Physiological research, 2019, 10-25, Volume: 68, Issue:5

    Topics: Animals; Chemokine CXCL2; Cytoprotection; Disease Models, Animal; Free Radical Scavengers; Glutathio

2019
Influence of alpha lipoic acid on antioxidant status in D-galactosamine-induced hepatic injury.
    Toxicology and industrial health, 2008, Volume: 24, Issue:10

    Topics: Analysis of Variance; Animals; Antioxidants; Biomarkers; Catalase; Chemical and Drug Induced Liver I

2008
Dihydrolipoyl histidinate zinc complex, a new antioxidant, attenuates hepatic ischemia-reperfusion injury in rats.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:11

    Topics: Alanine Transaminase; Animals; Antimycin A; Antioxidants; Aspartate Aminotransferases; Biomarkers; B

2011
[Clinical and experimental aspects of thioctic acid].
    Giornale di clinica medica, 1955, Volume: 36, Issue:12

    Topics: Acids; Animals; Diabetes Mellitus, Experimental; Glycosides; Lipid Metabolism; Liver Diseases; Thioc

1955
[Experimental and clinical research on thioctic acid].
    Archivio "E. Maragliano" di patologia e clinica, 1956, Volume: 12, Issue:6

    Topics: Liver Diseases; Organic Chemicals; Thioctic Acid; Vitamin A; Vitamin K; Vitamins

1956
[Thioctic acid in allyl alcohol induced liver necrosis].
    Arztliche Forschung, 1957, May-10, Volume: 11, Issue:5

    Topics: Alcohols; Humans; Liver Diseases; Propanols; Thioctic Acid; Vitamins

1957
[Thioctic acid, hepatotropic biocatalyzer; its role in the treatment of hepatic coma].
    Revue medicale de la Suisse romande, 1957, Volume: 77, Issue:7

    Topics: Coma; Hepatic Encephalopathy; Humans; Liver Diseases; Organic Chemicals; Thioctic Acid; Vitamin A; V

1957
[Effect of thioctic acid on liver lesions after temporary cholestasis; experimental study].
    Archivio italiano di chirurgia, 1957, Volume: 82, Issue:5

    Topics: Bile Ducts; Cholestasis; Common Bile Duct; Humans; Liver Diseases; Thioctic Acid; Vitamins

1957
[Clinical use of thioctic acid in liver patients subjected to surgical intervention].
    Minerva chirurgica, 1957, Oct-15, Volume: 12, Issue:19

    Topics: Biliary Tract; Biliary Tract Surgical Procedures; Humans; Liver Diseases; Thioctic Acid; Vitamins

1957
[Protective action of thioctic acid on hepatic lesions due to repeated barbituric narcosis; experimental research].
    Acta anaesthesiologica, 1957, Volume: 8, Issue:6

    Topics: Gastrointestinal Diseases; Liver Diseases; Stupor; Thioctic Acid; Thiopental; Vitamin A; Vitamin K;

1957
[Thioctic acid and liver function. I. Influence of thioctic acid on the blood amino acid curve after intravenous loading with glycine in normal subjects and in liver disease patients].
    Archivio "E. Maragliano" di patologia e clinica, 1958, Volume: 14, Issue:4

    Topics: Amino Acids; Digestion; Glycine; Glycine Agents; Humans; Liver Diseases; Thioctic Acid; Vitamin A; V

1958
[Thioctic acid and hepatic function. II. Influence of thioctic acid-cocarboxylase association on amino-acidemic curve by endovenous administration of glycocoll in normal subjects and in liver patients].
    Archivio "E. Maragliano" di patologia e clinica, 1958, Volume: 14, Issue:6

    Topics: Glycine; Glycine Agents; Humans; Liver Diseases; Thiamine Pyrophosphate; Thioctic Acid; Vitamin A; V

1958
Effects of thioctic acid and adenosine triphosphate on liver diseases. I. Influences of thioctic acid and adenosine triphosphate on the liver of the mice damaged with carbon tetrachloride.
    The Journal of vitaminology, 1961, Mar-10, Volume: 7

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Carbon Tetrachloride; Leadership; Liver Diseas

1961
Effects of thioctic acid and adenosine triphosphate on liver diseases. II. Clinical effects of thioctic acid and adenosine triphosphate on hepatic coma.
    The Journal of vitaminology, 1961, Mar-10, Volume: 7

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Hepatic Encephalopathy; Humans; Liver Diseases; Thiocti

1961
[Studies on nutrition and hepatic injury. 4. Studies on experimental fatty liver; effects of addition of lipoic acid, orotic acid, lvsine, threonine, and fermented sovbeans].
    Paediatria Japonica, 1961, Volume: 65

    Topics: Fatty Liver; Glycine max; Liver Diseases; Lysine; Nutritional Status; Orotic Acid; Thioctic Acid; Th

1961
[Clinical considerations on the therapeutic effects of the thioctic acid B-group vitamins combination in some diseases of the liver].
    Gazzetta medica italiana, 1960, Volume: 119

    Topics: Liver Diseases; Organic Chemicals; Thioctic Acid; Vitamin A; Vitamin B Complex; Vitamins

1960
[The effect of lipoic acid on degradation of cortisone in experimental fatty liver].
    Zeitschrift fur die gesamte experimentelle Medizin, 1961, Volume: 134

    Topics: Cortisone; Fatty Liver; Liver Diseases; Thioctic Acid

1961
[Thioctic acid in experimental liver diseases caused by selenium. Behavior of the transaminase activity and histological picture. Note II].
    Il Policlinico. Sezione medica, 1959, Volume: 66

    Topics: Liver Diseases; Liver Function Tests; Selenium; Selenium Compounds; Thioctic Acid; Transaminases

1959
[Effect of thioctic acid on the activity of different serum enzymes in chronic liver diseases].
    Acta hepato-splenologica, 1962, Volume: 9

    Topics: Cholinesterases; Humans; Liver Diseases; Liver Function Tests; Oxidoreductases; Thioctic Acid; Trans

1962
[Considerations on the clinical use of a special pharmacological combination in various forms of liver disease].
    Minerva medica, 1962, Jun-06, Volume: 53

    Topics: Amino Acids; Gastric Mucins; Humans; Lactones; Liver Diseases; Liver Extracts; Thioctic Acid; Vitami

1962
[Importance and criticism of liver drugs].
    Sogo igaku. Medicine, 1963, Volume: 20

    Topics: Asparagine; Glucuronates; Liver Diseases; Methionine; Thioctic Acid; Uracil Nucleotides

1963
[On the treatment of the premenstrual syndrome and menstruation disorders by means of hepatic therapy].
    La Riforma medica, 1963, Jan-19, Volume: 77

    Topics: Cysteine; Female; Gluconates; Humans; Liver Diseases; Liver Extracts; Menstruation Disturbances; Met

1963
[The blood pyruvic and lactic acid levels in patients with liver disease, and changes following the administration of thioctic acid].
    Taehan Uihak Hyophoe chi. The Journal of the Korean Medical Association, 1963, Jan-20, Volume: 6

    Topics: Humans; Lactates; Lactic Acid; Liver Diseases; Pyruvates; Thioctic Acid

1963
[Metabolic significance of alpha-lipoic acid. IV. Action of alpha-lipoic acid on ceruloplasmin and transferrin in different pathological conditions. (Preliminary report)].
    Arquivo de patologia, 1963, Volume: 35

    Topics: Ceruloplasmin; Copper; Glomerulonephritis; Hemochromatosis; Iron; Liver Diseases; Neuritis; Oxidatio

1963
[Clinical applicability of thioctic acid].
    Munchener medizinische Wochenschrift (1950), 1962, Oct-26, Volume: 104

    Topics: Humans; Liver Diseases; Thioctic Acid

1962
[EFFECTS OF THE ORAL ADMINISTRATION OF HEPATOPROTECTIVE DRUGS ON THE PREVENTION OF HEPATIC DISORDERS AFTER LUNG SURGERY].
    Kyobu geka. The Japanese journal of thoracic surgery, 1964, Volume: 17

    Topics: Administration, Oral; Humans; Liver Diseases; Niacin; Nicotinic Acids; Pantothenic Acid; Pharmacolog

1964
[CLINICAL RESEARCH ON PYRUVIC ACID METABOLISM IN LIVER DISEASES. II. EFFECTS OF DIFFERENT DRUGS ON THE PYRUVIC ACID BLOOD LEVEL IN LIVER DISEASES].
    Acta medicinae Okayama, 1964, Volume: 18

    Topics: Adrenal Cortex Hormones; Asparagine; Blood Chemical Analysis; Glucose; Hepatitis; Hepatitis A; Liver

1964
[Clinical observations on thioctic acid (lipoic acid); preliminary report].
    Arzneimittel-Forschung, 1955, Volume: 5, Issue:1

    Topics: Acids; Humans; Liver Diseases; Thioctic Acid

1955
[The action of thioctic acid on hepatic damage due to ethionine].
    Sicilia sanitaria, 1959, Volume: 12

    Topics: Abdominal Injuries; Ethionine; Liver; Liver Diseases; Thioctic Acid

1959
[The effects of thioctic acid on the fatty degeneration of regenerating rat liver].
    Acta biologica et medica Germanica, 1959, Volume: 3

    Topics: Animals; Liver Diseases; Rats; Thioctic Acid; Vitamin A; Vitamins

1959
[Curative liver protection by thioctic acid].
    Pharmaceutica acta Helvetiae, 1959, Volume: 34

    Topics: Liver Diseases; Thioctic Acid

1959
[Observations on the treatment of liver diseases by means of coenzyme A, thioctic acid, hepatic extract and vitamin B-12].
    Gazzetta medica italiana, 1961, Volume: 120

    Topics: Coenzyme A; Coenzymes; Corrinoids; Hematinics; Liver Diseases; Liver Extracts; Thioctic Acid; Vitami

1961
Prophylaxis against lipopolysaccharide-induced liver injuries by lipoic acid in rats.
    Pharmacological research, 2003, Volume: 48, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

2003
Mitigation of oxidative stress in cyclophosphamide-challenged hepatic tissue by DL-alpha-lipoic acid.
    Molecular and cellular biochemistry, 2005, Volume: 272, Issue:1-2

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Cyclophosphamide; Lipid Peroxidation;

2005
Hepatocellular injury of nonischemic liver tissue after selective clamping in rats--protective action by pharmacological pretreatment with lipoic acid.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2007, Volume: 39, Issue:6

    Topics: Animals; Antioxidants; Constriction; Disease Models, Animal; Ischemia; Lipid Peroxidation; Liver; Li

2007
The potential protective role of alpha-lipoic acid against acetaminophen-induced hepatic and renal damage.
    Toxicology, 2008, Jan-20, Volume: 243, Issue:3

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidan

2008
Antioxidant DL-alpha lipoic acid as an attenuator of adriamycin induced hepatotoxicity in rat model.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:12

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Chemical and Drug Induced Liver Injury; Doxorubi

2007
[Contribution to the treatment of chronic liver diseases with Thioctacid].
    Ceskoslovenska gastroenterologie a vyziva, 1982, Volume: 36, Issue:8

    Topics: Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Thioctic Acid

1982
A practical assay of lipoate in biologic fluids and liver in health and disease.
    Free radical biology & medicine, 1998, Volume: 25, Issue:4-5

    Topics: Absorption; Adult; Animals; Biological Assay; Body Fluids; Humans; Kidney Diseases; Kinetics; Liver;

1998
[Thioctic acid in liver diseases].
    ZFA. Zeitschrift fur Allgemeinmedizin, 1979, Oct-31, Volume: 55, Issue:30

    Topics: Adult; Aged; Bilirubin; Female; gamma-Glutamyltransferase; Humans; Liver Diseases; Male; Middle Aged

1979
[Dosage of lipoic acid preparations in chronic diseases of the liver].
    Klinicheskaia meditsina, 1977, Volume: 55, Issue:10

    Topics: Chronic Disease; Humans; Liver Diseases; Thioctic Acid

1977
Hepatobiliary imaging: a comparison of 99Tcm-dihydrothioctic acid and 99Tcm-pyridoxylidene glutamate in the non-jaundiced patient.
    The British journal of radiology, 1978, Volume: 51, Issue:611

    Topics: Adult; Aged; Gallbladder; Gallbladder Diseases; Glutamates; Humans; Liver; Liver Diseases; Male; Mid

1978
Thioctic acid in treatment of hepatotoxic mushroom (Phalloides) poisoning.
    The New England journal of medicine, 1979, Feb-15, Volume: 300, Issue:7

    Topics: Humans; Liver Diseases; Mushroom Poisoning; Thioctic Acid

1979
[Effect of sodium dehydrocholate, thioctanic acid and posterior pituitary lobe hormonal complex on the secretory efficiency of the liver as determined by the method of long-term intravenous infusion of indocyanine green].
    Polskie Archiwum Medycyny Wewnetrznej, 1976, Volume: 56, Issue:6

    Topics: Adult; Dehydrocholic Acid; Humans; Indocyanine Green; Infusions, Parenteral; Liver; Liver Diseases;

1976
[Changes of serum acetoin level in patients with liver diseases after intravenous administration of alpha-lipoic acid].
    Casopis lekaru ceskych, 1975, Nov-07, Volume: 114, Issue:45

    Topics: Acetoin; Butanones; Humans; Injections, Intravenous; Liver Diseases; Thioctic Acid

1975
[What is the current status of therapeutic possibilities in severe juandice?].
    La Presse medicale, 1968, Mar-23, Volume: 76, Issue:14

    Topics: Adolescent; Adult; Child; Coenzyme A; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Hyp

1968
[Clinical trial of a new coenzyme complex in patients with liver disease].
    La Clinica terapeutica, 1970, Feb-15, Volume: 52, Issue:3

    Topics: Adolescent; Adult; Aged; Coenzyme A; Female; Gallbladder Diseases; Humans; Liver Diseases; Male; Mid

1970
[Treatment of chronic liver disease with lipoic acid].
    Klinicheskaia meditsina, 1967, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Thiocti

1967
[Use of lipoic acid in complex therapy of patients with liver diseases].
    Vrachebnoe delo, 1969, Volume: 5

    Topics: Adult; Amides; Female; Humans; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Thioctic Acid

1969
[Lipoic (thioctic) acid and its significance in hepatology].
    Sovetskaia meditsina, 1969, Volume: 32, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Arteriosclerosis; Carbohydrate Metabolism; Diabetes Mellitus; Humans;

1969
[Treatment of chronic diseases of the liver parenchyma with thioctic acid].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Jun-15, Volume: 25, Issue:24

    Topics: Adult; Aged; Chronic Disease; Female; Humans; Liver Diseases; Male; Middle Aged; Thioctic Acid

1970
[Use of lipoic acid and its amide in chronic liver diseases].
    Sovetskaia meditsina, 1971, Volume: 34, Issue:12

    Topics: Amides; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Thioctic Acid

1971
[Pharmacological studies on liver-acting agents 2. Effects of so-called liver drugs on the ethionine-damaged liver].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1966, Nov-20, Volume: 62, Issue:6

    Topics: Animals; Bile Acids and Salts; Blood Proteins; Chemical and Drug Induced Liver Injury; Ethionine; Gl

1966