Page last updated: 2024-10-19

thioctic acid and Lactic Acidosis

thioctic acid has been researched along with Lactic Acidosis in 5 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Research Excerpts

ExcerptRelevanceReference
"PDHc deficiency was demonstrated in muscle and fibroblasts without detectable PDHA1 mutations."1.36Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. ( Briones, P; Font, A; Pineda, M; Quintana, E; Ribes, A; Tort, F; Vilaseca, MA, 2010)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tort, F2
Ferrer-Cortès, X1
Thió, M1
Navarro-Sastre, A1
Matalonga, L1
Quintana, E2
Bujan, N1
Arias, A1
García-Villoria, J1
Acquaviva, C1
Vianey-Saban, C1
Artuch, R1
García-Cazorla, À1
Briones, P2
Ribes, A2
Orsucci, D1
Filosto, M1
Siciliano, G1
Mancuso, M1
Pineda, M1
Font, A1
Vilaseca, MA1
Yoshida, I1
Sweetman, L1
Kulovich, S1
Nyhan, WL1
Robinson, BH1
Byrd, DJ1
Krohn, HP1
Winkler, L1
Steinborn, C1
Hadam, M1
Brodehl, J1
Hunneman, DH1

Reviews

1 review available for thioctic acid and Lactic Acidosis

ArticleYear
Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction.
    Nutrition reviews, 2009, Volume: 67, Issue:8

    Topics: Acidosis, Lactic; Animals; Antioxidants; Carnitine; Creatine; Dietary Supplements; Electron Transpor

2009

Other Studies

4 other studies available for thioctic acid and Lactic Acidosis

ArticleYear
Mutations in the lipoyltransferase LIPT1 gene cause a fatal disease associated with a specific lipoylation defect of the 2-ketoacid dehydrogenase complexes.
    Human molecular genetics, 2014, Apr-01, Volume: 23, Issue:7

    Topics: Acidosis, Lactic; Acyltransferases; Amino Acid Metabolism, Inborn Errors; Animals; Cells, Cultured;

2014
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Acidosis, Lactic; Adult; Amino Acid Sequence; Base Sequence; Biomarkers; Blepharoptosis; Cells, Cult

2010
Effect of lipoic acid in a patient with defective activity of pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase, and branched-chain keto acid dehydrogenase.
    Pediatric research, 1990, Volume: 27, Issue:1

    Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acidosis, Lactic; Acidosis

1990
Neonatal pyruvate dehydrogenase deficiency with lipoate responsive lactic acidaemia and hyperammonaemia.
    European journal of pediatrics, 1989, Volume: 148, Issue:6

    Topics: Acidosis, Lactic; Ammonia; Female; Humans; Infant, Newborn; Pyruvate Dehydrogenase Complex Deficienc

1989