thioctic acid has been researched along with Kidney Failure, Chronic in 13 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination of oral mixed tocopherols and ALA treatment for 2 months does not influence biomarkers of oxidative stress and inflammation in patients with stage 3 to 4 CKD." | 5.15 | Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease. ( Himmelfarb, J; Ikizler, TA; Kane, J; Le, P; McMonagle, E; Ramos, LF; Shintani, A; Wu, P, 2011) |
| "Vitamin D deficiency is a common health complication in patients with chronic kidney disease and can be treated with an abundance of classical and advanced pharmaceutics." | 2.77 | A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world. ( Bea, L; Larkin, J; Sharma, A, 2012) |
| "In an open-label, parallel-group study involving 16 patients (8 with severely reduced renal function, 8 with end-stage renal disease needing hemodialysis), the effect of renal function on the pharmacokinetics, metabolism, and safety and of alpha-lipoic acid (thioctic acid) was evaluated by comparing the pharmacokinetic parameters with those of a reference group of 8 healthy subjects." | 2.71 | Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease. ( Achenbach, H; Hermann, R; Preiss, C; Preiss, R; Ruus, P; Teichert, J; Tuemmers, T, 2005) |
| "Thioctic acid treatment was discontinued 2 days after admission." | 1.37 | Thioctic acid-induced acute cholestatic hepatitis. ( Castiglioni, T; Ridruejo, E; Silva, MO, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohlová, M | 1 |
| Amorim, CG | 1 |
| Araújo, A | 1 |
| Santos-Silva, A | 1 |
| Solich, P | 1 |
| Montenegro, MCBSM | 1 |
| Safa, J | 2 |
| Ardalan, MR | 1 |
| Rezazadehsaatlou, M | 1 |
| Mesgari, M | 1 |
| Mahdavi, R | 2 |
| Jadid, MP | 1 |
| Iciek, M | 2 |
| Marcykiewicz, B | 1 |
| Bilska-Wilkosz, A | 1 |
| Sokołowska-Jeżewicz, M | 1 |
| Kłapcińska, J | 1 |
| Ergür, BU | 1 |
| Çilaker Mıcılı, S | 1 |
| Yılmaz, O | 1 |
| Akokay, P | 1 |
| Ramos, LF | 1 |
| Kane, J | 1 |
| McMonagle, E | 1 |
| Le, P | 1 |
| Wu, P | 1 |
| Shintani, A | 1 |
| Ikizler, TA | 1 |
| Himmelfarb, J | 1 |
| Sokołowska, M | 1 |
| Niedzielska, E | 1 |
| Bilska, A | 1 |
| Lorenc-Koci, E | 1 |
| Włodek, L | 1 |
| Ridruejo, E | 1 |
| Castiglioni, T | 1 |
| Silva, MO | 1 |
| Khabbazi, T | 1 |
| Pour-Abdollahi, P | 1 |
| Yu, X | 1 |
| Liu, H | 1 |
| Zou, J | 1 |
| Zhu, J | 1 |
| Xu, X | 1 |
| Ding, X | 1 |
| Larkin, J | 1 |
| Bea, L | 1 |
| Sharma, A | 1 |
| Teichert, J | 1 |
| Tuemmers, T | 1 |
| Achenbach, H | 1 |
| Preiss, C | 1 |
| Hermann, R | 1 |
| Ruus, P | 1 |
| Preiss, R | 1 |
| Chang, JW | 1 |
| Lee, EK | 1 |
| Kim, TH | 1 |
| Min, WK | 1 |
| Chun, S | 1 |
| Lee, KU | 1 |
| Kim, SB | 1 |
| Park, JS | 1 |
| Reddi, AS | 1 |
| Baskin, S | 1 |
| Wassel, E | 1 |
| DeAngelis, B | 1 |
| Baker, H | 1 |
1 review available for thioctic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease.
Topics: Antioxidants; Biocompatible Materials; Cellulose; Humans; Inflammation; Kidney Failure, Chronic; Mem | 2019 |
6 trials available for thioctic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
Effects of alpha lipoic acid supplementation on serum levels of IL-8 and TNF-α in patient with ESRD undergoing hemodialysis.
Topics: Adult; Aged; Antioxidants; Diabetic Nephropathies; Dietary Supplements; Double-Blind Method; Female; | 2014 |
Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.
Topics: Administration, Oral; Aged; Antioxidants; Biomarkers; C-Reactive Protein; Double-Blind Method; Drug | 2011 |
Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.
Topics: Adult; Aged; Antioxidants; C-Reactive Protein; Cholesterol; Dietary Supplements; Double-Blind Method | 2012 |
A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world.
Topics: Anemia; Antioxidants; C-Reactive Protein; Cholecalciferol; Cost-Benefit Analysis; Dietary Supplement | 2012 |
Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease.
Topics: Adult; Aged; Antioxidants; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Renal | 2005 |
Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study.
Topics: Adult; Antioxidants; Arginine; Biomarkers; C-Reactive Protein; Cholesterol; Chromatography, High Pre | 2007 |
6 other studies available for thioctic acid and Kidney Failure, Chronic
| Article | Year |
|---|---|
The effect of lipoate on anaerobic cysteine metabolism in erythrocytes of patients treated with peritoneal dialysis.
Topics: Adult; Aged; Cysteine; Dietary Supplements; Erythrocytes; Female; Humans; Kidney Failure, Chronic; M | 2014 |
The effects of α-lipoic acid on aortic injury and hypertension in the rat remnant kidney (5/6 nephrectomy) model.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Abdominal; Blood Pressure; Dietary Supplements; | 2015 |
The effect of the uremic toxin cyanate (CNO⁻) on anaerobic cysteine metabolism and oxidative processes in the rat liver: a protective effect of lipoate.
Topics: Animals; Antioxidants; Cyanates; Cysteine; Hydrogen Sulfide; Kidney Failure, Chronic; Lipid Peroxida | 2011 |
Thioctic acid-induced acute cholestatic hepatitis.
Topics: Antioxidants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Diabetes Mellitus, | 2011 |
Oxidative stress in 5/6 nephrectomized rat model: effect of alpha-lipoic acid.
Topics: Animals; Antioxidants; Disease Models, Animal; Kidney; Kidney Failure, Chronic; Kidney Function Test | 2012 |
Plasma alpha-lipoic acid and total glutathione levels in patients on maintenance hemodialysis.
Topics: Female; Glutathione; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Thioctic Acid | 1999 |