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thioctic acid and Ischemia

thioctic acid has been researched along with Ischemia in 13 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia."7.74Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008)
"To evaluate the protective effects of two naturally occurring antioxidants, α-Lipoic acid and coenzyme Q10 on the response to in vitro ischemia of the rabbit urinary bladder."3.77The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion. ( Leggett, RE; Levin, RM; Radu, F; Schuler, C, 2011)
"To determine the efficacy of coenzyme Q10 (CoQ10) and alpha-lipoic acid (alpha-LA), either alone or in combination, to protect the contractile responses of the rabbit urinary bladder from damage caused by repetitive stimulation in the presence or absence of in vitro ischemia."3.74Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. ( Levin, RM; Lin, WY; Rehfuss, A; Schuler, C, 2008)
"Ischemia was performed in adult male rats by bilateral femoral artery occlusion, then ischemia-reperfusion was done for 1 day and 7 days."1.72Ameliorative role of alpha-lipoic acid in renal cortical structural damage, induced by limb ischemia-reperfusion injury in the rat. ( Mubarak, HA; Othman, MA; Sayed, MM, 2022)
" (c) Ethanol mediated a dose-response enhancement of the contractile dysfunctions caused by in vitro ischemia."1.33Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid. ( Danek, M; Haugaard, N; Levin, RM; Whitbeck, C, 2005)
"To reduce reperfusion injury, conditions were ameliorated including the treatment with antioxidants, lipoate or dihydrolipoate."1.31Lipoate ameliorates ischemia-reperfusion in animal models. ( Freisleben, HJ, 2000)
"Ischemia was produced by the ligature of each of the supplying arteries to the sciatic-tibial nerve of the right hind-limb for predetermined periods of time (either 3 or 5 h), followed by the release of the ligatures, resulting in reperfusion."1.30Alpha-lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve. ( Low, PA; Mitsui, M; Mitsui, Y; Schmelzer, JD; Tritschler, HJ; Zollman, PJ, 1999)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's2 (15.38)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Ding, Y1
Zhang, Y1
Zhang, W1
Shang, J1
Xie, Z1
Chen, C1
Othman, MA1
Mubarak, HA1
Sayed, MM1
Dogan Ozcil, M1
Ozcan, O1
Hakverdi, S1
Bayraktar, HS1
Dirican, E1
Kacmaz, F1
Aydın, A1
Yıldırım, AM1
Radu, F1
Leggett, RE1
Schuler, C2
Levin, RM3
Danek, M1
Whitbeck, C1
Haugaard, N1
Duenschede, F2
Westermann, S2
Miesner, I1
Albrecht-Schöck, S2
Kneist, W1
Korenkov, M1
Schad, A2
Dutkowski, P1
Kiemer, AK2
Junginger, T2
Erbes, K1
Riegler, N1
Ewald, P1
Kircher, A1
Miesmer, I1
Gockel, I1
Lin, WY1
Rehfuss, A1
Block, F1
Schwarz, M1
Mitsui, Y1
Schmelzer, JD1
Zollman, PJ1
Mitsui, M1
Tritschler, HJ1
Low, PA1
Freisleben, HJ1
Roldán, EJ1
Kerzberg, EM1
Boveris, A1

Reviews

1 review available for thioctic acid and Ischemia

ArticleYear
Effects of Lipoic Acid on Ischemia-Reperfusion Injury.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Antioxidants; Cognition; Humans; Ischemia; Reperfusion Injury; Spinal Cord Injuries; Thioct

2021

Other Studies

12 other studies available for thioctic acid and Ischemia

ArticleYear
Ameliorative role of alpha-lipoic acid in renal cortical structural damage, induced by limb ischemia-reperfusion injury in the rat.
    Ultrastructural pathology, 2022, Jan-02, Volume: 46, Issue:1

    Topics: Animals; Antioxidants; Ischemia; Kidney; Male; Rats; Reperfusion Injury; Thioctic Acid

2022
Impact of Enoxaparin +α Lipoic acid combination on oxidative stress, follicle development and apoptotic damage in ovarian ischemia reperfusion model.
    European review for medical and pharmacological sciences, 2022, Volume: 26, Issue:18

    Topics: Animals; Antioxidants; Biomarkers; Catalase; Enoxaparin; Female; Follicle Stimulating Hormone; Gluta

2022
Effects of alpha lipoic acid on ischemia-reperfusion injury in rat hindlimb ischemia model.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2016, Volume: 22, Issue:6

    Topics: Animals; Antioxidants; Disease Models, Animal; Hindlimb; Infusions, Parenteral; Ischemia; Male; Musc

2016
The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion.
    Molecular and cellular biochemistry, 2011, Volume: 355, Issue:1-2

    Topics: Animals; Antioxidants; Fatty Acids, Nonesterified; Ischemia; Lipid Peroxidation; Male; Malondialdehy

2011
Effect of ethanol on the response of the rat urinary bladder to in vitro ischemia: protective effect of alpha-lipoic acid.
    Molecular and cellular biochemistry, 2005, Volume: 271, Issue:1-2

    Topics: Animals; Carbachol; Ethanol; In Vitro Techniques; Ischemia; Male; Muscle Contraction; Protective Age

2005
Hepatocellular injury of nonischemic liver tissue after selective clamping in rats--protective action by pharmacological pretreatment with lipoic acid.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2007, Volume: 39, Issue:6

    Topics: Animals; Antioxidants; Constriction; Disease Models, Animal; Ischemia; Lipid Peroxidation; Liver; Li

2007
Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model.
    World journal of gastroenterology, 2007, Jul-21, Volume: 13, Issue:27

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Caspase 3; Caspase 9;

2007
Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia.
    Urology, 2008, Volume: 72, Issue:1

    Topics: Animals; Antioxidants; Carbachol; Electric Stimulation; Electron Transport Chain Complex Proteins; I

2008
Effects of antioxidants on ischemic retinal dysfunction.
    Experimental eye research, 1997, Volume: 64, Issue:4

    Topics: Animals; Antioxidants; Electroretinography; Ischemia; Male; Rats; Rats, Wistar; Retinal Vessels; Thi

1997
Alpha-lipoic acid provides neuroprotection from ischemia-reperfusion injury of peripheral nerve.
    Journal of the neurological sciences, 1999, Feb-01, Volume: 163, Issue:1

    Topics: Action Potentials; Animals; Gait; Hindlimb; Ischemia; Male; Muscle, Skeletal; Neuroprotective Agents

1999
Lipoate ameliorates ischemia-reperfusion in animal models.
    Clinical hemorheology and microcirculation, 2000, Volume: 23, Issue:2-4

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Aorta, Thoracic; Cell Hypoxia; Constriction; Creatine

2000
[Kinetics of chemoluminiscence of rat intestine during ischemia and reperfusion].
    Medicina, 1989, Volume: 49, Issue:4

    Topics: Analysis of Variance; Animals; Free Radicals; Intestines; Ischemia; Ligation; Luminescent Measuremen

1989
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