thioctic acid has been researched along with Injury, Myocardial Reperfusion in 20 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to evaluate the efficacy of CMX-2043 in an animal model of myocardial IRI and to establish effective dosing conditions." | 1.43 | CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury. ( Baguisi, A; Beeuwkes, R; Casale, RA; Kates, SA; Lader, AS; Stewart, K, 2016) |
| "The etiology of diabetic complications is strongly associated with increased oxidative stress." | 1.39 | Ischemia-reperfusion injury of the isolated diabetic rat heart: effect of the antioxidant stobadine. ( Broskova, Z; Knezl, V; Kyselova, Z, 2013) |
| "To reduce reperfusion injury, conditions were ameliorated including the treatment with antioxidants, lipoate or dihydrolipoate." | 1.31 | Lipoate ameliorates ischemia-reperfusion in animal models. ( Freisleben, HJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 6 (30.00) | 29.6817 |
| 2010's | 7 (35.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mokhtari, B | 1 |
| Abdoli-Shadbad, M | 1 |
| Alihemmati, A | 2 |
| Javadi, A | 1 |
| Badalzadeh, R | 2 |
| Qi, B | 1 |
| Zheng, Y | 1 |
| Gao, W | 1 |
| Qi, Z | 1 |
| Gong, Y | 1 |
| Liu, Y | 2 |
| Wang, Y | 1 |
| Cheng, X | 1 |
| Ning, M | 1 |
| Lang, Y | 1 |
| Feng, J | 1 |
| Li, T | 1 |
| Gholami, S | 1 |
| Deng, C | 1 |
| Sun, Z | 1 |
| Tong, G | 1 |
| Yi, W | 1 |
| Ma, L | 1 |
| Zhao, B | 1 |
| Cheng, L | 1 |
| Zhang, J | 1 |
| Cao, F | 1 |
| Yi, D | 1 |
| Broskova, Z | 1 |
| Kyselova, Z | 1 |
| Knezl, V | 1 |
| Cao, X | 1 |
| Chen, A | 1 |
| Yang, P | 1 |
| Song, X | 1 |
| Li, Z | 1 |
| Wang, X | 1 |
| Wang, L | 1 |
| Li, Y | 1 |
| Dudek, M | 1 |
| Knutelska, J | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Zygmunt, M | 1 |
| Bilska-Wilkosz, A | 1 |
| Iciek, M | 1 |
| Otto, M | 1 |
| Żytka, I | 1 |
| Sapa, J | 1 |
| Włodek, L | 1 |
| Filipek, B | 1 |
| Baguisi, A | 1 |
| Casale, RA | 1 |
| Kates, SA | 1 |
| Lader, AS | 1 |
| Stewart, K | 1 |
| Beeuwkes, R | 1 |
| Ghibu, S | 1 |
| Lauzier, B | 1 |
| Delemasure, S | 1 |
| Amoureux, S | 1 |
| Sicard, P | 1 |
| Vergely, C | 1 |
| Muresan, A | 1 |
| Mogosan, C | 1 |
| Rochette, L | 1 |
| Hagiwara, S | 1 |
| Teshima, Y | 1 |
| Takahashi, N | 1 |
| Koga, H | 1 |
| Saikawa, T | 1 |
| Noguchi, T | 1 |
| He, L | 1 |
| Liu, B | 1 |
| Dai, Z | 1 |
| Zhang, HF | 1 |
| Zhang, YS | 1 |
| Luo, XJ | 1 |
| Ma, QL | 1 |
| Peng, J | 1 |
| Koufaki, M | 2 |
| Detsi, A | 2 |
| Theodorou, E | 1 |
| Kiziridi, C | 1 |
| Calogeropoulou, T | 2 |
| Vassilopoulos, A | 1 |
| Kourounakis, AP | 2 |
| Rekka, E | 1 |
| Kourounakis, PN | 2 |
| Gaitanaki, C | 2 |
| Papazafiri, P | 2 |
| Schönheit, K | 1 |
| Gille, L | 1 |
| Nohl, H | 1 |
| Szabados, E | 1 |
| Fischer, GM | 1 |
| Gallyas, F | 1 |
| Kispal, G | 1 |
| Sumegi, B | 1 |
| Coombes, JS | 1 |
| Powers, SK | 1 |
| Demirel, HA | 1 |
| Jessup, J | 1 |
| Vincent, HK | 1 |
| Hamilton, KL | 1 |
| Naito, H | 1 |
| Shanely, RA | 1 |
| Sen, CK | 1 |
| Packer, L | 2 |
| Ji, LL | 1 |
| Freisleben, HJ | 2 |
| Roditis, A | 1 |
| Tsiakitzis, K | 1 |
| Beis, I | 1 |
| Serbinova, E | 1 |
| Khwaja, S | 1 |
| Reznick, AZ | 1 |
| Gao, TL | 1 |
| Huang, YZ | 1 |
20 other studies available for thioctic acid and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Alpha-lipoic acid preconditioning plus ischemic postconditioning provides additional protection against myocardial reperfusion injury of diabetic rats: modulation of autophagy and mitochondrial function.
Topics: Animals; Autophagy; Diabetes Mellitus, Experimental; Ischemic Postconditioning; Ischemic Preconditio | 2022 |
Alpha-lipoic acid impedes myocardial ischemia-reperfusion injury, myocardial apoptosis, and oxidative stress by regulating HMGB1 expression.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cytokines; HMGB1 Prot | 2022 |
Alpha-lipoic acid enhances ischemic postconditioning-mediated improvement of myocardial infarction and apoptosis in diabetic rats with ischemia/reperfusion injury.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Diabetes Mellitus, Experimental; Ischemic Postcondit | 2023 |
α-Lipoic acid reduces infarct size and preserves cardiac function in rat myocardial ischemia/reperfusion injury through activation of PI3K/Akt/Nrf2 pathway.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Nucleus; Creatine Kinase; Disease Models, Animal; Gene | 2013 |
Ischemia-reperfusion injury of the isolated diabetic rat heart: effect of the antioxidant stobadine.
Topics: Animals; Antioxidants; Carbolines; Diabetes Complications; Male; Myocardial Reperfusion Injury; Rats | 2013 |
Alpha-lipoic acid protects cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cells, Cultured; Green Fluor | 2013 |
Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Arrhythmias, C | 2014 |
CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Cardiovascular Agents; Cytoprotection; Dipeptid | 2016 |
Antioxidant properties of alpha-lipoic acid: effects on red blood membrane permeability and adaptation of isolated rat heart to reversible ischemia.
Topics: Adaptation, Physiological; Animals; Antioxidants; Cell Membrane Permeability; Chromans; Erythrocytes | 2009 |
New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Heart; Histidine; Male; Membra | 2011 |
Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Apoptosis; Caspas | 2012 |
Synthesis of chroman analogues of lipoic acid and evaluation of their activity against reperfusion arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Chromans; Drug Evaluation, Preclinical; Male; Myocardial Reperfusion | 2004 |
Effect of alpha-lipoic acid and dihydrolipoic acid on ischemia/reperfusion injury of the heart and heart mitochondria.
Topics: Animals; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury | 1995 |
Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart.
Topics: Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Antioxidants; DNA Damage; Enzyme Act | 1999 |
Effect of combined supplementation with vitamin E and alpha-lipoic acid on myocardial performance during in vivo ischaemia-reperfusion.
Topics: Animals; Antioxidants; Benzene Derivatives; Blood Pressure; Dietary Supplements; Disease Models, Ani | 2000 |
Lipoic acid reduces ischemia-reperfusion injury in animal models.
Topics: Adenosine Triphosphatases; Animals; Creatine Kinase; Disease Models, Animal; Heart; Hindlimb; In Vit | 2000 |
Lipoate ameliorates ischemia-reperfusion in animal models.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Aorta, Thoracic; Cell Hypoxia; Constriction; Creatine | 2000 |
Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Cardiac; Benzopyrans; Chromans; Depressi | 2001 |
Thioctic acid protects against ischemia-reperfusion injury in the isolated perfused Langendorff heart.
Topics: Animals; Diet; Dihydrolipoamide Dehydrogenase; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid P | 1992 |
[Effects of lipoic acid on reperfusion induced arrhythmias and myocardiac action potential alterations induced by free radical generating system].
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Female; Free Radical Scavengers; Free Radicals; Gu | 1991 |