thioctic acid has been researched along with Hypoxia in 15 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Excerpt | Relevance | Reference |
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" During the period of hypoxia, the volunteers received as a short-term treatment either 1200 mg thioctic acid, or N-acetylcysteine 600 mg or placebo (0." | 9.10 | Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. ( Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A, 2002) |
" During the period of hypoxia, the volunteers received as a short-term treatment either 1200 mg thioctic acid, or N-acetylcysteine 600 mg or placebo (0." | 5.10 | Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. ( Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A, 2002) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (6.67) | 18.7374 |
1990's | 4 (26.67) | 18.2507 |
2000's | 1 (6.67) | 29.6817 |
2010's | 8 (53.33) | 24.3611 |
2020's | 1 (6.67) | 2.80 |
Authors | Studies |
---|---|
Wang, Y | 1 |
Zheng, Y | 1 |
Qi, B | 1 |
Liu, Y | 1 |
Cheng, X | 1 |
Feng, J | 1 |
Gao, W | 1 |
Li, T | 1 |
Paredes, F | 1 |
Sheldon, K | 1 |
Lassègue, B | 1 |
Williams, HC | 1 |
Faidley, EA | 1 |
Benavides, GA | 1 |
Torres, G | 1 |
Sanhueza-Olivares, F | 1 |
Yeligar, SM | 1 |
Griendling, KK | 1 |
Darley-Usmar, V | 1 |
San Martin, A | 1 |
Casciato, P | 1 |
Ambrosi, N | 1 |
Caro, F | 1 |
Vazquez, M | 1 |
Müllen, E | 1 |
Gadano, A | 1 |
de Santibañes, E | 1 |
de Santibañes, M | 1 |
Zandomeni, M | 1 |
Chahdi, M | 1 |
Lazarte, JC | 1 |
Biagiola, DA | 1 |
Iaquinandi, JC | 1 |
Santofimia-Castaño, P | 1 |
Iovanna, J | 1 |
Incardona, C | 1 |
Chuluyan, E | 1 |
Pérez-López, A | 1 |
Martin-Rincon, M | 1 |
Santana, A | 1 |
Perez-Suarez, I | 1 |
Dorado, C | 1 |
Calbet, JAL | 1 |
Morales-Alamo, D | 1 |
Abuyassin, B | 1 |
Badran, M | 1 |
Ayas, NT | 1 |
Laher, I | 1 |
Yoo, TH | 1 |
Lee, JH | 1 |
Chun, HS | 1 |
Chi, SG | 1 |
Röhnert, P | 1 |
Schröder, UH | 1 |
Ziabreva, I | 1 |
Täger, M | 1 |
Reymann, KG | 1 |
Striggow, F | 1 |
Volchegorskiĭ, IA | 1 |
Rassokhina, LM | 1 |
Miroshnichenko, IIu | 1 |
Xie, R | 1 |
Li, X | 1 |
Ling, Y | 1 |
Shen, C | 1 |
Wu, X | 1 |
Xu, W | 1 |
Gao, X | 1 |
Haramaki, N | 2 |
Packer, L | 2 |
Assadnazari, H | 3 |
Zimmer, G | 3 |
Freisleben, HJ | 1 |
Werk, W | 1 |
Leibfritz, D | 1 |
Schepkin, V | 1 |
Wood, JG | 1 |
Johnson, JS | 1 |
Mattioli, LF | 1 |
Gonzalez, NC | 1 |
Freudenthaler, SM | 1 |
Schreeb, KH | 1 |
Wiese, A | 1 |
Pilz, J | 1 |
Gleiter, CH | 1 |
Wideman, J | 1 |
3 trials available for thioctic acid and Hypoxia
Article | Year |
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α-lipoic acid reduces postreperfusion syndrome in human liver transplantation - a pilot study.
Topics: Aged; Alarmins; Apoptosis; Biopsy; Cold Ischemia; Cytokines; Double-Blind Method; Female; Follow-Up | 2018 |
Antioxidants Facilitate High-intensity Exercise IL-15 Expression in Skeletal Muscle.
Topics: Adult; Antioxidants; Ascorbic Acid; Double-Blind Method; Exercise; Exercise Test; Humans; Hypoxia; I | 2019 |
Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.
Topics: Acetylcysteine; Adult; Antioxidants; Area Under Curve; Erythropoietin; Free Radical Scavengers; Huma | 2002 |
12 other studies available for thioctic acid and Hypoxia
Article | Year |
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α-Lipoic acid alleviates myocardial injury and induces M2b macrophage polarization after myocardial infarction via HMGB1/NF-kB signaling pathway.
Topics: Animals; Cytokines; Heart Injuries; HMGB1 Protein; Hypoxia; Macrophages; Mice; Myocardial Infarction | 2023 |
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.
Topics: Animals; Coenzyme A Ligases; Humans; Hypoxia; Ketoglutarate Dehydrogenase Complex; Lipoylation; Mice | 2018 |
The antioxidant α-lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea.
Topics: Animals; Antioxidants; Disease Models, Animal; Hypoxia; Inflammation; Kidney; Kidney Diseases; Male; | 2019 |
α-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-κB induction of RPS6KA4.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Dose-Response Relationship, Drug; G1 Phase Cell Cycl | 2013 |
Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cell Death; Disease Models, Animal; Ethidium; Fluoresceins; Gerbillinae; Gl | 2012 |
[Antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes].
Topics: Alloxan; Animals; Conditioning, Classical; Diabetes Mellitus, Experimental; Diabetic Neuropathies; D | 2011 |
Alpha-lipoic acid pre- and post-treatments provide protection against in vitro ischemia-reperfusion injury in cerebral endothelial cells via Akt/mTOR signaling.
Topics: Analysis of Variance; Animals; Antioxidants; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug A | 2012 |
Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid.
Topics: Analysis of Variance; Animals; Biomarkers; Coronary Circulation; Food, Fortified; Hypoxia; In Vitro | 1993 |
Cardioprotective efficiency of dihydrolipoic acid in working rat hearts during hypoxia and reoxygenation. 31P nuclear magnetic resonance investigations.
Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Heart; Heart Diseases; Hypoxia; In Vitro Technique | 1993 |
The influence of vitamin E and dihydrolipoic acid on cardiac energy and glutathione status under hypoxia-reoxygenation.
Topics: Animals; Antioxidants; Energy Metabolism; Glutathione; Glutathione Disulfide; Heart; Hypoxia; Male; | 1995 |
Systemic hypoxia promotes leukocyte-endothelial adherence via reactive oxidant generation.
Topics: Animals; Antioxidants; Catalase; Cell Adhesion; Endothelium, Vascular; Hypoxia; Leukocytes; Male; Mi | 1999 |
Regulation of thiols in the brain. 4. Glutathione--cystine transhydrogenase activity during hypoxia and its substrate specificity in different parts of the rat brain.
Topics: Animals; Brain; Brain Stem; Cattle; Cerebellum; Cystine; Cytoplasm; Disulfides; Glutathione Reductas | 1974 |