thioctic acid has been researched along with Hypoxia in 15 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " During the period of hypoxia, the volunteers received as a short-term treatment either 1200 mg thioctic acid, or N-acetylcysteine 600 mg or placebo (0." | 9.10 | Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. ( Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A, 2002) |
| " During the period of hypoxia, the volunteers received as a short-term treatment either 1200 mg thioctic acid, or N-acetylcysteine 600 mg or placebo (0." | 5.10 | Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans. ( Freudenthaler, SM; Gleiter, CH; Pilz, J; Schreeb, KH; Wiese, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Y | 1 |
| Zheng, Y | 1 |
| Qi, B | 1 |
| Liu, Y | 1 |
| Cheng, X | 1 |
| Feng, J | 1 |
| Gao, W | 1 |
| Li, T | 1 |
| Paredes, F | 1 |
| Sheldon, K | 1 |
| Lassègue, B | 1 |
| Williams, HC | 1 |
| Faidley, EA | 1 |
| Benavides, GA | 1 |
| Torres, G | 1 |
| Sanhueza-Olivares, F | 1 |
| Yeligar, SM | 1 |
| Griendling, KK | 1 |
| Darley-Usmar, V | 1 |
| San Martin, A | 1 |
| Casciato, P | 1 |
| Ambrosi, N | 1 |
| Caro, F | 1 |
| Vazquez, M | 1 |
| Müllen, E | 1 |
| Gadano, A | 1 |
| de Santibañes, E | 1 |
| de Santibañes, M | 1 |
| Zandomeni, M | 1 |
| Chahdi, M | 1 |
| Lazarte, JC | 1 |
| Biagiola, DA | 1 |
| Iaquinandi, JC | 1 |
| Santofimia-Castaño, P | 1 |
| Iovanna, J | 1 |
| Incardona, C | 1 |
| Chuluyan, E | 1 |
| Pérez-López, A | 1 |
| Martin-Rincon, M | 1 |
| Santana, A | 1 |
| Perez-Suarez, I | 1 |
| Dorado, C | 1 |
| Calbet, JAL | 1 |
| Morales-Alamo, D | 1 |
| Abuyassin, B | 1 |
| Badran, M | 1 |
| Ayas, NT | 1 |
| Laher, I | 1 |
| Yoo, TH | 1 |
| Lee, JH | 1 |
| Chun, HS | 1 |
| Chi, SG | 1 |
| Röhnert, P | 1 |
| Schröder, UH | 1 |
| Ziabreva, I | 1 |
| Täger, M | 1 |
| Reymann, KG | 1 |
| Striggow, F | 1 |
| Volchegorskiĭ, IA | 1 |
| Rassokhina, LM | 1 |
| Miroshnichenko, IIu | 1 |
| Xie, R | 1 |
| Li, X | 1 |
| Ling, Y | 1 |
| Shen, C | 1 |
| Wu, X | 1 |
| Xu, W | 1 |
| Gao, X | 1 |
| Haramaki, N | 2 |
| Packer, L | 2 |
| Assadnazari, H | 3 |
| Zimmer, G | 3 |
| Freisleben, HJ | 1 |
| Werk, W | 1 |
| Leibfritz, D | 1 |
| Schepkin, V | 1 |
| Wood, JG | 1 |
| Johnson, JS | 1 |
| Mattioli, LF | 1 |
| Gonzalez, NC | 1 |
| Freudenthaler, SM | 1 |
| Schreeb, KH | 1 |
| Wiese, A | 1 |
| Pilz, J | 1 |
| Gleiter, CH | 1 |
| Wideman, J | 1 |
3 trials available for thioctic acid and Hypoxia
| Article | Year |
|---|---|
α-lipoic acid reduces postreperfusion syndrome in human liver transplantation - a pilot study.
Topics: Aged; Alarmins; Apoptosis; Biopsy; Cold Ischemia; Cytokines; Double-Blind Method; Female; Follow-Up | 2018 |
Antioxidants Facilitate High-intensity Exercise IL-15 Expression in Skeletal Muscle.
Topics: Adult; Antioxidants; Ascorbic Acid; Double-Blind Method; Exercise; Exercise Test; Humans; Hypoxia; I | 2019 |
Influence of controlled hypoxia and radical scavenging agents on erythropoietin and malondialdehyde concentrations in humans.
Topics: Acetylcysteine; Adult; Antioxidants; Area Under Curve; Erythropoietin; Free Radical Scavengers; Huma | 2002 |
12 other studies available for thioctic acid and Hypoxia
| Article | Year |
|---|---|
α-Lipoic acid alleviates myocardial injury and induces M2b macrophage polarization after myocardial infarction via HMGB1/NF-kB signaling pathway.
Topics: Animals; Cytokines; Heart Injuries; HMGB1 Protein; Hypoxia; Macrophages; Mice; Myocardial Infarction | 2023 |
Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.
Topics: Animals; Coenzyme A Ligases; Humans; Hypoxia; Ketoglutarate Dehydrogenase Complex; Lipoylation; Mice | 2018 |
The antioxidant α-lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea.
Topics: Animals; Antioxidants; Disease Models, Animal; Hypoxia; Inflammation; Kidney; Kidney Diseases; Male; | 2019 |
α-Lipoic acid prevents p53 degradation in colon cancer cells by blocking NF-κB induction of RPS6KA4.
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Dose-Response Relationship, Drug; G1 Phase Cell Cycl | 2013 |
Insufficient endogenous redox buffer capacity may underlie neuronal vulnerability to cerebral ischemia and reperfusion.
Topics: Animals; Brain Ischemia; Cell Death; Disease Models, Animal; Ethidium; Fluoresceins; Gerbillinae; Gl | 2012 |
[Antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes].
Topics: Alloxan; Animals; Conditioning, Classical; Diabetes Mellitus, Experimental; Diabetic Neuropathies; D | 2011 |
Alpha-lipoic acid pre- and post-treatments provide protection against in vitro ischemia-reperfusion injury in cerebral endothelial cells via Akt/mTOR signaling.
Topics: Analysis of Variance; Animals; Antioxidants; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug A | 2012 |
Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid.
Topics: Analysis of Variance; Animals; Biomarkers; Coronary Circulation; Food, Fortified; Hypoxia; In Vitro | 1993 |
Cardioprotective efficiency of dihydrolipoic acid in working rat hearts during hypoxia and reoxygenation. 31P nuclear magnetic resonance investigations.
Topics: Adenosine Triphosphate; Animals; Creatine Kinase; Heart; Heart Diseases; Hypoxia; In Vitro Technique | 1993 |
The influence of vitamin E and dihydrolipoic acid on cardiac energy and glutathione status under hypoxia-reoxygenation.
Topics: Animals; Antioxidants; Energy Metabolism; Glutathione; Glutathione Disulfide; Heart; Hypoxia; Male; | 1995 |
Systemic hypoxia promotes leukocyte-endothelial adherence via reactive oxidant generation.
Topics: Animals; Antioxidants; Catalase; Cell Adhesion; Endothelium, Vascular; Hypoxia; Leukocytes; Male; Mi | 1999 |
Regulation of thiols in the brain. 4. Glutathione--cystine transhydrogenase activity during hypoxia and its substrate specificity in different parts of the rat brain.
Topics: Animals; Brain; Brain Stem; Cattle; Cerebellum; Cystine; Cytoplasm; Disulfides; Glutathione Reductas | 1974 |