thioctic acid has been researched along with Heart Disease, Ischemic in 10 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To reduce reperfusion injury, conditions were ameliorated including the treatment with antioxidants, lipoate or dihydrolipoate." | 1.31 | Lipoate ameliorates ischemia-reperfusion in animal models. ( Freisleben, HJ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dudek, M | 1 |
| Knutelska, J | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Zygmunt, M | 1 |
| Bilska-Wilkosz, A | 1 |
| Iciek, M | 1 |
| Otto, M | 1 |
| Żytka, I | 1 |
| Sapa, J | 1 |
| Włodek, L | 1 |
| Filipek, B | 1 |
| Hagiwara, S | 1 |
| Teshima, Y | 1 |
| Takahashi, N | 1 |
| Koga, H | 1 |
| Saikawa, T | 1 |
| Noguchi, T | 1 |
| Wang, X | 1 |
| Yu, Y | 1 |
| Ji, L | 1 |
| Liang, X | 1 |
| Zhang, T | 1 |
| Hai, CX | 1 |
| Makeeva, AV | 1 |
| Popova, TN | 1 |
| Matasova, LV | 1 |
| Yama, IN | 1 |
| Schönheit, K | 1 |
| Gille, L | 1 |
| Nohl, H | 1 |
| Sumegi, B | 1 |
| Butwell, NB | 1 |
| Malloy, CR | 1 |
| Sherry, AD | 1 |
| Haramaki, N | 1 |
| Packer, L | 2 |
| Assadnazari, H | 1 |
| Zimmer, G | 1 |
| Freisleben, HJ | 2 |
| Coombes, JS | 1 |
| Powers, SK | 1 |
| Hamilton, KL | 1 |
| Demirel, HA | 1 |
| Shanely, RA | 1 |
| Zergeroglu, MA | 1 |
| Sen, CK | 1 |
| Ji, LL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of The Effect of Alpha Lipoic Acid Administration on Oxidative Stress Markers and Occurrence of No-Reflow Phenomenon in Post Myocardial Infarction Patients[NCT05360602] | 60 participants (Anticipated) | Interventional | 2022-07-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for thioctic acid and Heart Disease, Ischemic
| Article | Year |
|---|---|
Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Arrhythmias, C | 2014 |
New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Disease Models, Animal; Heart; Histidine; Male; Membra | 2011 |
Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Catalase; Creatine Kinase; Glutathione; Male; M | 2011 |
Effects of lipoic acid on citrate content, aconitate hydratase activity, and oxidative status during myocardial ischemia in rats.
Topics: Aconitate Hydratase; Animals; Antioxidants; Citric Acid; Male; Myocardial Ischemia; Myocardium; Oxid | 2008 |
Effect of alpha-lipoic acid and dihydrolipoic acid on ischemia/reperfusion injury of the heart and heart mitochondria.
Topics: Animals; Hemodynamics; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury | 1995 |
Lipoamide influences substrate selection in post-ischaemic perfused rat hearts.
Topics: Acetates; Acetylation; Animals; Aspartic Acid; Binding, Competitive; Carbon Isotopes; Glutamates; Gl | 1994 |
Cardiac recovery during post-ischemic reperfusion is improved by combination of vitamin E with dihydrolipoic acid.
Topics: Analysis of Variance; Animals; Biomarkers; Coronary Circulation; Food, Fortified; Hypoxia; In Vitro | 1993 |
Lipoic acid reduces ischemia-reperfusion injury in animal models.
Topics: Adenosine Triphosphatases; Animals; Creatine Kinase; Disease Models, Animal; Heart; Hindlimb; In Vit | 2000 |
Improved cardiac performance after ischemia in aged rats supplemented with vitamin E and alpha-lipoic acid.
Topics: Animals; Antioxidants; Blood Pressure; Dietary Supplements; Heart; Lipid Peroxidation; Male; Myocard | 2000 |
Lipoate ameliorates ischemia-reperfusion in animal models.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Aorta, Thoracic; Cell Hypoxia; Constriction; Creatine | 2000 |