Page last updated: 2024-10-19

thioctic acid and Genetic Predisposition

thioctic acid has been researched along with Genetic Predisposition in 3 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Research Excerpts

ExcerptRelevanceReference
"PDHc deficiency was demonstrated in muscle and fibroblasts without detectable PDHA1 mutations."1.36Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. ( Briones, P; Font, A; Pineda, M; Quintana, E; Ribes, A; Tort, F; Vilaseca, MA, 2010)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brenner, SR1
Quintana, E1
Pineda, M1
Font, A1
Vilaseca, MA1
Tort, F1
Ribes, A1
Briones, P1
Ishida, Y1
Ohara, T1
Okuno, Y1
Ito, T1
Hirota, Y1
Furukawa, K1
Sakaguchi, K1
Ogawa, W1
Kasuga, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Double-blinded, Placebo-controlled Trial of Idebenone in the Prevention of Episodic Migraine[NCT04151472]Phase 3180 participants (Anticipated)Interventional2021-12-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for thioctic acid and Genetic Predisposition

ArticleYear
Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs.
    Neurology, 2010, Jan-12, Volume: 74, Issue:2

    Topics: Brain Diseases, Metabolic; Chronic Disease; Disease Progression; DNA, Mitochondrial; Genetic Predisp

2010
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain.
    Journal of inherited metabolic disease, 2010, Volume: 33 Suppl 3

    Topics: Acidosis, Lactic; Adult; Amino Acid Sequence; Base Sequence; Biomarkers; Blepharoptosis; Cells, Cult

2010
Alpha-lipoic acid and insulin autoimmune syndrome.
    Diabetes care, 2007, Volume: 30, Issue:9

    Topics: Adult; Antioxidants; Autoantibodies; Autoimmune Diseases; Female; Genetic Predisposition to Disease;

2007