thioctic acid has been researched along with Experimental Radiation Injuries in 12 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inflammation was decreased and recovery time was shortened in the ALA + RT group compared with the RT group." | 1.43 | Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice. ( Choi, BH; Choi, HS; Hahm, JR; Jeong, BK; Jeong, H; Jung, JH; Jung, MH; Kang, KM; Kim, JH; Song, JH; Woo, SH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Farhood, B | 1 |
| Hassanzadeh, G | 1 |
| Amini, P | 1 |
| Shabeeb, D | 1 |
| Musa, AE | 1 |
| Khodamoradi, E | 1 |
| Mohseni, M | 1 |
| Aliasgharzadeh, A | 1 |
| Moradi, H | 1 |
| Najafi, M | 1 |
| Kim, JH | 4 |
| Jeong, BK | 4 |
| Jang, SJ | 1 |
| Yun, JW | 1 |
| Jung, MH | 4 |
| Kang, KM | 4 |
| Kim, TG | 1 |
| Woo, SH | 4 |
| Said, RS | 1 |
| Mohamed, HA | 1 |
| Kassem, DH | 1 |
| Jung, JH | 3 |
| Jung, J | 1 |
| Kim, SK | 1 |
| Hahm, JR | 2 |
| Song, JH | 1 |
| Jeong, H | 1 |
| Choi, HS | 1 |
| Choi, BH | 1 |
| Kim, KM | 1 |
| Kim, JP | 1 |
| Park, JJ | 1 |
| Villasana, LE | 1 |
| Rosenthal, RA | 1 |
| Doctrow, SR | 1 |
| Pfankuch, T | 1 |
| Zuloaga, DG | 1 |
| Garfinkel, AM | 1 |
| Raber, J | 1 |
| Kropachova, K | 1 |
| Mishurova, E | 1 |
| Ramakrishnan, N | 1 |
| Wolfe, WW | 1 |
| Catravas, GN | 1 |
| Bodó, K | 1 |
| Benkö, G | 1 |
| Dilley, JV | 1 |
| Koćmierska-Grodzka, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients[NCT05023863] | Phase 2/Phase 3 | 70 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for thioctic acid and Experimental Radiation Injuries
| Article | Year |
|---|---|
Mitigation of Radiation-induced Gastrointestinal System Injury using Resveratrol or Alpha-lipoic Acid: A Pilot Histopathological Study.
Topics: Animals; Colon; Duodenum; Gamma Rays; Jejunum; Male; Mice; Radiation Injuries, Experimental; Radiati | 2020 |
Alpha-Lipoic Acid Ameliorates Radiation-Induced Salivary Gland Injury by Preserving Parasympathetic Innervation in Rats.
Topics: Animals; Body Weight; Male; Organ Size; Radiation Injuries, Experimental; Rats, Sprague-Dawley; Sali | 2020 |
Alpha-lipoic acid effectively attenuates ionizing radiation-mediated testicular dysfunction in rats: Crosstalk of NF-ĸB, TGF-β, and PPAR-ϒ pathways.
Topics: Animals; Antioxidants; Cytokines; Epithelium; Gamma Rays; Male; NF-kappa B; PPAR gamma; Radiation In | 2020 |
Alpha lipoic acid attenuates radiation-induced thyroid injury in rats.
Topics: Animals; Antioxidants; Cytokines; Disease Models, Animal; Fibrosis; Male; Oxidative Stress; Radiatio | 2014 |
Effect of alpha-lipoic acid on radiation-induced small intestine injury in mice.
Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Gamma | 2016 |
Protective effects of alpha lipoic acid on radiation-induced salivary gland injury in rats.
Topics: Animals; Male; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiotherapy; Rats; Ra | 2016 |
Effects of alpha-lipoic acid on associative and spatial memory of sham-irradiated and 56Fe-irradiated C57BL/6J male mice.
Topics: Animals; Antioxidants; Brain; Conditioning, Psychological; Cranial Irradiation; Dentate Gyrus; Iron; | 2013 |
[Flavobion and thioctacid lessen irradiation-induced latent injury of the liver].
Topics: Animals; Chromosome Aberrations; Hepatectomy; Liver; Liver Regeneration; Male; Radiation Injuries, E | 1992 |
Radioprotection of hematopoietic tissues in mice by lipoic acid.
Topics: Animals; Cell Survival; Colony-Forming Units Assay; Hematopoietic Stem Cells; Male; Mice; Radiation | 1992 |
The effect of radioprotective compounds on brain serotonine metabolisation of irradiated experimental animals.
Topics: Animals; beta-Aminoethyl Isothiourea; Brain; Hydroxyindoleacetic Acid; Male; Mice; Radiation Injurie | 1985 |
In vivo and in vitro chelation of plutonium by alpha-lipoic acid and DTPA. BNWL-714.
Topics: Animals; In Vitro Techniques; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Thio | 1968 |
[Radiotoxins and their part in pathogenesis of radiation sickness].
Topics: Animals; Mice; Parabiosis; Peptide Hydrolases; Peroxides; Plants; Radiation Injuries, Experimental; | 1970 |