thioctic acid has been researched along with Dysesthesia in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerlinger, I | 1 |
| Wepner, U | 1 |
| Ziegler, D | 1 |
| Ametov, A | 1 |
| Barinov, A | 1 |
| Dyck, PJ | 1 |
| Gurieva, I | 1 |
| Low, PA | 1 |
| Munzel, U | 1 |
| Yakhno, N | 1 |
| Raz, I | 1 |
| Novosadova, M | 1 |
| Maus, J | 1 |
| Samigullin, R | 1 |
| Balabolkin, MI | 1 |
| Kreminskaia, VM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dose Finding and Tolerability Study of Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Peripheral Neuropathy[NCT01313117] | Phase 1/Phase 2 | 9 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2) Randomised, Double-blind,Placebo-controlled Multicentre Trial With 4 Parallel Groups[NCT00328601] | Phase 3 | 170 participants | Interventional | 2005-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 9 |
Based on acceptable adverse event (AE) profile and continual reassessment method dose escalation. (NCT01313117)
Timeframe: 4 months
| Intervention | mg (Number) |
|---|---|
| Alpha Lipoic Acid | 500 |
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 7 |
1 review available for thioctic acid and Dysesthesia
| Article | Year |
|---|---|
[Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice].
Topics: Acetamides; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Burning Mouth Syndrome | 2012 |
1 trial available for thioctic acid and Dysesthesia
| Article | Year |
|---|---|
Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.
Topics: Administration, Oral; Aged; Diabetic Neuropathies; Female; Foot; Humans; Male; Middle Aged; Pain; Pa | 2006 |
Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.
Topics: Administration, Oral; Aged; Diabetic Neuropathies; Female; Foot; Humans; Male; Middle Aged; Pain; Pa | 2006 |
Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.
Topics: Administration, Oral; Aged; Diabetic Neuropathies; Female; Foot; Humans; Male; Middle Aged; Pain; Pa | 2006 |
Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial.
Topics: Administration, Oral; Aged; Diabetic Neuropathies; Female; Foot; Humans; Male; Middle Aged; Pain; Pa | 2006 |
2 other studies available for thioctic acid and Dysesthesia
| Article | Year |
|---|---|
[Evidence-based management of diabetic polyneuropathy. "Burning feet" alarm signal].
Topics: Amines; Combined Modality Therapy; Cyclohexanecarboxylic Acids; Diabetic Foot; Diabetic Neuropathies | 2004 |
[Diabetic neuropathy].
Topics: Acupuncture Therapy; Adjuvants, Immunologic; Antioxidants; Combined Modality Therapy; Diabetic Neuro | 2000 |