thioctic acid has been researched along with Diffuse Myofascial Pain Syndrome in 2 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Drug therapy for fibromyalgia is limited by incomplete efficacy and dose-limiting adverse effects (AEs)." | 7.30 | Combination analgesic development for enhanced clinical efficacy (the CADENCE trial): a double-blind, controlled trial of an alpha-lipoic acid-pregabalin combination for fibromyalgia pain. ( Gilron, I; Holden, RR; Milev, R; Robb, S; Towheed, T; Tu, D, 2023) |
| "Drug therapy for fibromyalgia is limited by incomplete efficacy and dose-limiting adverse effects (AEs)." | 3.30 | Combination analgesic development for enhanced clinical efficacy (the CADENCE trial): a double-blind, controlled trial of an alpha-lipoic acid-pregabalin combination for fibromyalgia pain. ( Gilron, I; Holden, RR; Milev, R; Robb, S; Towheed, T; Tu, D, 2023) |
| "Fibromyalgia is a common and challenging chronic pain disorder with few, if any, highly effective and well-tolerated treatments." | 3.01 | Double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain: the IMPALA trial. ( Gilron, I; Gray, C; Holden, R; Milev, R; Robb, S; Towheed, T; Tu, D; Wang, L; Ziegler, D, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gilron, I | 2 |
| Robb, S | 2 |
| Tu, D | 2 |
| Holden, RR | 1 |
| Milev, R | 2 |
| Towheed, T | 2 |
| Holden, R | 1 |
| Ziegler, D | 1 |
| Wang, L | 1 |
| Gray, C | 1 |
2 trials available for thioctic acid and Diffuse Myofascial Pain Syndrome
| Article | Year |
|---|---|
Combination analgesic development for enhanced clinical efficacy (the CADENCE trial): a double-blind, controlled trial of an alpha-lipoic acid-pregabalin combination for fibromyalgia pain.
Topics: Analgesics; Double-Blind Method; Fibromyalgia; gamma-Aminobutyric Acid; Humans; Pain; Pregabalin; Th | 2023 |
Double-blind, randomized, placebo-controlled crossover trial of alpha-lipoic acid for the treatment of fibromyalgia pain: the IMPALA trial.
Topics: Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; Male; Thioctic Acid; Treatmen | 2021 |