thioctic acid has been researched along with Deficiency, Vitamin B in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rowin, J | 1 |
| GRIGNANI, F | 1 |
| BERNARDINI, V | 1 |
| OTANI, M | 1 |
| GAL, EM | 1 |
| RAZEVSKA, DE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dose Finding and Tolerability Study of Alpha-lipoic Acid in Patients at Risk for Paclitaxel Induced Peripheral Neuropathy[NCT01313117] | Phase 1/Phase 2 | 9 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 9 |
Based on acceptable adverse event (AE) profile and continual reassessment method dose escalation. (NCT01313117)
Timeframe: 4 months
| Intervention | mg (Number) |
|---|---|
| Alpha Lipoic Acid | 500 |
(NCT01313117)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Alpha Lipoic Acid | 7 |
1 review available for thioctic acid and Deficiency, Vitamin B
| Article | Year |
|---|---|
Integrative neuromuscular medicine: Neuropathy and neuropathic pain: Consider the alternatives.
Topics: Acetylcarnitine; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Diet; Diet Therapy; Dietary Supp | 2019 |
3 other studies available for thioctic acid and Deficiency, Vitamin B
| Article | Year |
|---|---|
[Metabolic effects of thioctic acid in rats fed a vitamin B1 deficient diet].
Topics: Animals; Cholelithiasis; Diet; Rats; Thiamine; Thiamine Deficiency; Thioctic Acid; Vitamin B Deficie | 1958 |
[Experimental studies on the tissue respiration, particularly on the TCA-cycle of isolated liver and diaphragm. 3. Studies on the O2 consumption of liver homogenate and diaphragm, taken from the thiamine deficient rats, response of Qo2 to panthotenic acid
Topics: Animals; Citric Acid Cycle; Diaphragm; Liver; Metabolism; Muscles; Pantothenic Acid; Phosphates; Rat | 1961 |
Studies on the in vivo metabolism of lipoic acid. 1. The fate of DL-lipoic acid-S35 in normal and thiamine-deficient rats.
Topics: Animals; Biochemical Phenomena; Lipid Metabolism; Rats; Thiamine; Thioctic Acid; Vitamin B Deficienc | 1960 |