thioctic acid has been researched along with Deficiency, Thiamine in 6 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prolonged exposure to the chemical intermediate, 1,3-dinitrobenzene (1,3-DNB), produces neuropathology in the central nervous system of rodents analogous to that observed in various conditions of acute energy deprivation including thiamine deficiency and Leigh's necrotizing encephalopathy." | 3.77 | 1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex. ( Miller, JA; Philbert, MA; Runkle, SA; Tjalkens, RB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, JA | 1 |
| Runkle, SA | 1 |
| Tjalkens, RB | 1 |
| Philbert, MA | 1 |
| GRIGNANI, F | 1 |
| BERNARDINI, V | 1 |
| OTANI, M | 1 |
| Dayan, AD | 1 |
| Ockenden, BG | 1 |
| Crome, L | 1 |
| Gal, EM | 1 |
| Wiberg, GS | 1 |
| Munro, IC | 1 |
| Morrison, AB | 1 |
6 other studies available for thioctic acid and Deficiency, Thiamine
| Article | Year |
|---|---|
1,3-Dinitrobenzene-induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex.
Topics: Animals; Antioxidants; Astrocytes; Blotting, Western; Cell Line; Dinitrobenzenes; Electrophoresis, P | 2011 |
[Metabolic effects of thioctic acid in rats fed a vitamin B1 deficient diet].
Topics: Animals; Cholelithiasis; Diet; Rats; Thiamine; Thiamine Deficiency; Thioctic Acid; Vitamin B Deficie | 1958 |
[Experimental studies on the tissue respiration, particularly on the TCA-cycle of isolated liver and diaphragm. 3. Studies on the O2 consumption of liver homogenate and diaphragm, taken from the thiamine deficient rats, response of Qo2 to panthotenic acid
Topics: Animals; Citric Acid Cycle; Diaphragm; Liver; Metabolism; Muscles; Pantothenic Acid; Phosphates; Rat | 1961 |
Necrotizing encephalomyelopathy of Leigh. Neuropathological findings in 8 cases.
Topics: Adolescent; Basal Ganglia; Brain Stem; Caudate Nucleus; Cerebral Ventricles; Child; Child, Preschool | 1970 |
Reversal of selective toxicity of (-)-alpha-lipoic acid by thiamine in thiamine-deficient rats.
Topics: Animals; Antimetabolites; In Vitro Techniques; Rats; Thiamine; Thiamine Deficiency; Thioctic Acid; U | 1965 |
Effect of cobalt ions on myocardial metabolism.
Topics: Animals; Caprylates; Centrifugation; Cobalt; Male; Manometry; Mitochondria; Myocardium; Oxygen Consu | 1967 |