thioctic acid has been researched along with Deficiency, Mental in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine." | 7.65 | Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976) |
| " This infant was found to have lactic acidosis, low cerebrospinal fluid glucose, hyperalaninemia, and increased levels of urine lactate, pyruvate and alanine." | 3.65 | Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid. ( Komiya, K; Maesaka, H; Misugi, K; Tada, K, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maesaka, H | 1 |
| Komiya, K | 1 |
| Misugi, K | 1 |
| Tada, K | 1 |
| Pincus, JH | 1 |
| Grover, WD | 1 |
| Auerbach, VH | 1 |
| Patel, MS | 1 |
| Dayan, AD | 1 |
| Ockenden, BG | 1 |
| Crome, L | 1 |
4 other studies available for thioctic acid and Deficiency, Mental
| Article | Year |
|---|---|
Hyperalaninemia hyperpyruvicemia and lactic acidosis due to pyruvate carboxylase deficiency of the liver; treatment with thiamine and lipoic acid.
Topics: Acidosis; Alanine; Female; Glucose; Humans; Infant; Intellectual Disability; Lactates; Liver; Metabo | 1976 |
Subacute necrotizing encephalomyelopathy (Leigh's disease): a consideration of clinical features and etiology.
Topics: Age Factors; Brain Stem; Carbon Dioxide; Chronic Disease; Encephalomalacia; Humans; Infant; Infant, | 1972 |
Biochemical studies and therapy in subacute necrotizing encephalomyelopathy (Leigh's syndrome).
Topics: Biotin; Brain; Brain Stem; Carboxy-Lyases; Encephalomalacia; Humans; Infant; Intellectual Disability | 1972 |
Necrotizing encephalomyelopathy of Leigh. Neuropathological findings in 8 cases.
Topics: Adolescent; Basal Ganglia; Brain Stem; Caudate Nucleus; Cerebral Ventricles; Child; Child, Preschool | 1970 |