thioctic acid has been researched along with Chronic Kidney Failure in 13 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination of oral mixed tocopherols and ALA treatment for 2 months does not influence biomarkers of oxidative stress and inflammation in patients with stage 3 to 4 CKD." | 5.15 | Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease. ( Himmelfarb, J; Ikizler, TA; Kane, J; Le, P; McMonagle, E; Ramos, LF; Shintani, A; Wu, P, 2011) |
| "Vitamin D deficiency is a common health complication in patients with chronic kidney disease and can be treated with an abundance of classical and advanced pharmaceutics." | 2.77 | A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world. ( Bea, L; Larkin, J; Sharma, A, 2012) |
| "In an open-label, parallel-group study involving 16 patients (8 with severely reduced renal function, 8 with end-stage renal disease needing hemodialysis), the effect of renal function on the pharmacokinetics, metabolism, and safety and of alpha-lipoic acid (thioctic acid) was evaluated by comparing the pharmacokinetic parameters with those of a reference group of 8 healthy subjects." | 2.71 | Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease. ( Achenbach, H; Hermann, R; Preiss, C; Preiss, R; Ruus, P; Teichert, J; Tuemmers, T, 2005) |
| "Thioctic acid treatment was discontinued 2 days after admission." | 1.37 | Thioctic acid-induced acute cholestatic hepatitis. ( Castiglioni, T; Ridruejo, E; Silva, MO, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohlová, M | 1 |
| Amorim, CG | 1 |
| Araújo, A | 1 |
| Santos-Silva, A | 1 |
| Solich, P | 1 |
| Montenegro, MCBSM | 1 |
| Safa, J | 2 |
| Ardalan, MR | 1 |
| Rezazadehsaatlou, M | 1 |
| Mesgari, M | 1 |
| Mahdavi, R | 2 |
| Jadid, MP | 1 |
| Iciek, M | 2 |
| Marcykiewicz, B | 1 |
| Bilska-Wilkosz, A | 1 |
| Sokołowska-Jeżewicz, M | 1 |
| Kłapcińska, J | 1 |
| Ergür, BU | 1 |
| Çilaker Mıcılı, S | 1 |
| Yılmaz, O | 1 |
| Akokay, P | 1 |
| Ramos, LF | 1 |
| Kane, J | 1 |
| McMonagle, E | 1 |
| Le, P | 1 |
| Wu, P | 1 |
| Shintani, A | 1 |
| Ikizler, TA | 1 |
| Himmelfarb, J | 1 |
| Sokołowska, M | 1 |
| Niedzielska, E | 1 |
| Bilska, A | 1 |
| Lorenc-Koci, E | 1 |
| Włodek, L | 1 |
| Ridruejo, E | 1 |
| Castiglioni, T | 1 |
| Silva, MO | 1 |
| Khabbazi, T | 1 |
| Pour-Abdollahi, P | 1 |
| Yu, X | 1 |
| Liu, H | 1 |
| Zou, J | 1 |
| Zhu, J | 1 |
| Xu, X | 1 |
| Ding, X | 1 |
| Larkin, J | 1 |
| Bea, L | 1 |
| Sharma, A | 1 |
| Teichert, J | 1 |
| Tuemmers, T | 1 |
| Achenbach, H | 1 |
| Preiss, C | 1 |
| Hermann, R | 1 |
| Ruus, P | 1 |
| Preiss, R | 1 |
| Chang, JW | 1 |
| Lee, EK | 1 |
| Kim, TH | 1 |
| Min, WK | 1 |
| Chun, S | 1 |
| Lee, KU | 1 |
| Kim, SB | 1 |
| Park, JS | 1 |
| Reddi, AS | 1 |
| Baskin, S | 1 |
| Wassel, E | 1 |
| DeAngelis, B | 1 |
| Baker, H | 1 |
1 review available for thioctic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease.
Topics: Antioxidants; Biocompatible Materials; Cellulose; Humans; Inflammation; Kidney Failure, Chronic; Mem | 2019 |
6 trials available for thioctic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
Effects of alpha lipoic acid supplementation on serum levels of IL-8 and TNF-α in patient with ESRD undergoing hemodialysis.
Topics: Adult; Aged; Antioxidants; Diabetic Nephropathies; Dietary Supplements; Double-Blind Method; Female; | 2014 |
Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.
Topics: Administration, Oral; Aged; Antioxidants; Biomarkers; C-Reactive Protein; Double-Blind Method; Drug | 2011 |
Effects of alpha-lipoic acid supplementation on inflammation, oxidative stress, and serum lipid profile levels in patients with end-stage renal disease on hemodialysis.
Topics: Adult; Aged; Antioxidants; C-Reactive Protein; Cholesterol; Dietary Supplements; Double-Blind Method | 2012 |
A cost effective complement to managing the vitamin D deficient and anemic dialysis patient in the bundled world.
Topics: Anemia; Antioxidants; C-Reactive Protein; Cholecalciferol; Cost-Benefit Analysis; Dietary Supplement | 2012 |
Pharmacokinetics of alpha-lipoic acid in subjects with severe kidney damage and end-stage renal disease.
Topics: Adult; Aged; Antioxidants; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Renal | 2005 |
Effects of alpha-lipoic acid on the plasma levels of asymmetric dimethylarginine in diabetic end-stage renal disease patients on hemodialysis: a pilot study.
Topics: Adult; Antioxidants; Arginine; Biomarkers; C-Reactive Protein; Cholesterol; Chromatography, High Pre | 2007 |
6 other studies available for thioctic acid and Chronic Kidney Failure
| Article | Year |
|---|---|
The effect of lipoate on anaerobic cysteine metabolism in erythrocytes of patients treated with peritoneal dialysis.
Topics: Adult; Aged; Cysteine; Dietary Supplements; Erythrocytes; Female; Humans; Kidney Failure, Chronic; M | 2014 |
The effects of α-lipoic acid on aortic injury and hypertension in the rat remnant kidney (5/6 nephrectomy) model.
Topics: Administration, Oral; Animals; Antioxidants; Aorta, Abdominal; Blood Pressure; Dietary Supplements; | 2015 |
The effect of the uremic toxin cyanate (CNO⁻) on anaerobic cysteine metabolism and oxidative processes in the rat liver: a protective effect of lipoate.
Topics: Animals; Antioxidants; Cyanates; Cysteine; Hydrogen Sulfide; Kidney Failure, Chronic; Lipid Peroxida | 2011 |
Thioctic acid-induced acute cholestatic hepatitis.
Topics: Antioxidants; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Diabetes Mellitus, | 2011 |
Oxidative stress in 5/6 nephrectomized rat model: effect of alpha-lipoic acid.
Topics: Animals; Antioxidants; Disease Models, Animal; Kidney; Kidney Failure, Chronic; Kidney Function Test | 2012 |
Plasma alpha-lipoic acid and total glutathione levels in patients on maintenance hemodialysis.
Topics: Female; Glutathione; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Thioctic Acid | 1999 |