thioctic acid and Choline Deficiency
thioctic acid has been researched along with Choline Deficiency in 4 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Choline Deficiency: A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Non-alcoholic steatohepatitis (NASH) is a liver disease that causes fat accumulation, inflammation and fibrosis." | 1.38 | Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. ( Kim, HS; Kim, JG; Kim, MK; Lee, IK; Lee, KU; Min, AK; Park, KG; Seo, HY, 2012) |
"Carnitine treatment increased the mRNA expression of carnitine palmitoyltransferase 1A and peroxisome proliferator-activated receptor-γ, and carnitine-lipoic acid further augmented the mRNA expression." | 1.37 | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. ( Cho, WK; Choi, HS; Hahm, JS; Jang, KS; Jeon, HJ; Jun, DW; Jun, JH; Kim, HJ; Kwon, HJ; Lee, HL; Lee, KN; Lee, MH; Lee, OY; Yoon, BC, 2011) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 3 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Veskovic, M | 1 |
Mladenovic, D | 1 |
Jorgacevic, B | 1 |
Stevanovic, I | 1 |
de Luka, S | 1 |
Radosavljevic, T | 1 |
Jun, DW | 1 |
Cho, WK | 1 |
Jun, JH | 1 |
Kwon, HJ | 1 |
Jang, KS | 1 |
Kim, HJ | 1 |
Jeon, HJ | 1 |
Lee, KN | 1 |
Lee, HL | 1 |
Lee, OY | 1 |
Yoon, BC | 1 |
Choi, HS | 1 |
Hahm, JS | 1 |
Lee, MH | 1 |
Min, AK | 1 |
Kim, MK | 1 |
Kim, HS | 1 |
Seo, HY | 1 |
Lee, KU | 1 |
Kim, JG | 1 |
Park, KG | 1 |
Lee, IK | 1 |
Perra, A | 1 |
Pibiri, M | 1 |
Sulas, P | 1 |
Simbula, G | 1 |
Ledda-Columbano, GM | 1 |
Columbano, A | 1 |
Other Studies
4 other studies available for thioctic acid and Choline Deficiency
Article | Year |
---|---|
Alpha-lipoic acid affects the oxidative stress in various brain structures in mice with methionine and choline deficiency.
Topics: Animals; Brain; Catalase; Cerebral Cortex; Choline Deficiency; Corpus Striatum; Disease Models, Anim | 2015 |
Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Carnitine; Carnitine O-Palmitoyltransferase; Choline Def | 2011 |
Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Antioxidants; Choline; Choline Deficiency; Cyto | 2012 |
Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model.
Topics: Animals; Antioxidants; Cell Death; Choline Deficiency; Lipid Peroxidation; Liver Neoplasms; Precance | 2008 |