thioctic acid has been researched along with Cardiovascular Diseases in 23 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eicosapentaenoic acid (EPA) and α-lipoic acid (α-LA) have been investigated for their beneficial effects on obesity and cardiovascular risk factors." | 9.27 | Untargeted metabolomic on urine samples after α-lipoic acid and/or eicosapentaenoic acid supplementation in healthy overweight/obese women. ( González-Navarro, CJ; Huerta, AE; Martínez, JA; Moreno-Aliaga, MJ; Ramos-López, O; Romo-Hualde, A, 2018) |
| "This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity." | 7.83 | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016) |
| "Eicosapentaenoic acid (EPA) and α-lipoic acid (α-LA) have been investigated for their beneficial effects on obesity and cardiovascular risk factors." | 5.27 | Untargeted metabolomic on urine samples after α-lipoic acid and/or eicosapentaenoic acid supplementation in healthy overweight/obese women. ( González-Navarro, CJ; Huerta, AE; Martínez, JA; Moreno-Aliaga, MJ; Ramos-López, O; Romo-Hualde, A, 2018) |
| "This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity." | 3.83 | Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016) |
| "The "cytokine storm" observed in patients with severe COVID-19 contributes to the destruction of the endothelium, leading to "acute respiratory distress syndrome" (ARDS), multiorgan failure, and death." | 2.72 | Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection. ( Ghibu, S; Rochette, L, 2021) |
| "The incidence of NIDDM is highest in economically developed nations, particularly the U." | 2.41 | Use of antioxidant nutrients in the prevention and treatment of type 2 diabetes. ( McDonald, RB; Ruhe, RC, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 5 (21.74) | 2.80 |
| Authors | Studies |
|---|---|
| Liao, S | 1 |
| Yang, W | 1 |
| Yu, T | 1 |
| Dai, L | 1 |
| Liu, X | 1 |
| Zhang, J | 1 |
| Zhao, J | 1 |
| Liu, C | 1 |
| Abdel Hamid, DZ | 1 |
| Nienaa, YA | 1 |
| Mostafa, TM | 1 |
| Pagano, G | 1 |
| Pallardó, FV | 1 |
| Lyakhovich, A | 1 |
| Tiano, L | 1 |
| Fittipaldi, MR | 1 |
| Toscanesi, M | 1 |
| Trifuoggi, M | 1 |
| Frank, J | 1 |
| Kisters, K | 1 |
| Stirban, OA | 1 |
| Obeid, R | 1 |
| Lorkowski, S | 1 |
| Wallert, M | 1 |
| Egert, S | 1 |
| Podszun, MC | 1 |
| Eckert, GP | 1 |
| Pettersen, JA | 1 |
| Venturelli, S | 1 |
| Classen, HG | 1 |
| Golombek, J | 1 |
| Rochette, L | 3 |
| Ghibu, S | 4 |
| Várkonyi, T | 1 |
| Körei, A | 1 |
| Putz, Z | 1 |
| Martos, T | 1 |
| Keresztes, K | 1 |
| Lengyel, C | 1 |
| Nyiraty, S | 1 |
| Stirban, A | 1 |
| Jermendy, G | 1 |
| Kempler, P | 1 |
| Romo-Hualde, A | 1 |
| Huerta, AE | 1 |
| González-Navarro, CJ | 1 |
| Ramos-López, O | 1 |
| Moreno-Aliaga, MJ | 1 |
| Martínez, JA | 1 |
| Tromba, L | 1 |
| Perla, FM | 1 |
| Carbotta, G | 1 |
| Chiesa, C | 1 |
| Pacifico, L | 1 |
| Sergienko, VA | 1 |
| Segin, VB | 1 |
| Samir, A | 1 |
| Sergienko, AA | 1 |
| Mohammadi, V | 1 |
| Khalili, M | 1 |
| Eghtesadi, S | 1 |
| Dehghani, S | 1 |
| Jazayeri, S | 1 |
| Aghababaee, SK | 1 |
| Sabour, H | 1 |
| Saberi, H | 1 |
| Eghtesadi, M | 1 |
| Gohari, MR | 1 |
| Skibska, B | 1 |
| Goraca, A | 1 |
| Cheserek, MJ | 1 |
| Wu, G | 1 |
| Li, L | 2 |
| Karangwa, E | 1 |
| Shi, Y | 1 |
| Le, G | 1 |
| Richard, C | 3 |
| Delemasure, S | 1 |
| Vergely, C | 3 |
| Mogosan, C | 1 |
| Muresan, A | 1 |
| Zeller, M | 2 |
| Cottin, Y | 2 |
| G D, X | 1 |
| J H, P | 1 |
| H L, S | 1 |
| L S, Z | 1 |
| McNeilly, AM | 1 |
| Davison, GW | 1 |
| Murphy, MH | 1 |
| Nadeem, N | 1 |
| Trinick, T | 1 |
| Duly, E | 1 |
| Novials, A | 1 |
| McEneny, J | 1 |
| Ghann, WE | 1 |
| Aras, O | 1 |
| Fleiter, T | 1 |
| Daniel, MC | 1 |
| Wollin, SD | 1 |
| Jones, PJ | 1 |
| Hadj, A | 1 |
| Pepe, S | 1 |
| Rosenfeldt, F | 1 |
| Tardif, JC | 1 |
| Rhéaume, E | 1 |
| Marley, R | 1 |
| Holt, S | 1 |
| Fernando, B | 1 |
| Harry, D | 1 |
| Anand, R | 1 |
| Goodier, D | 1 |
| Davies, S | 1 |
| Moore, K | 1 |
| Ruhe, RC | 1 |
| McDonald, RB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cellular and Molecular Effects of Lipoic Acid and Eicosapentaenoic Acid (EPA) on Adipose Tissue: Potential Application in Human Obesity[NCT01138774] | 103 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 reviews available for thioctic acid and Cardiovascular Diseases
| Article | Year |
|---|---|
Aging-Related Disorders and Mitochondrial Dysfunction: A Critical Review for Prospect Mitoprotective Strategies Based on Mitochondrial Nutrient Mixtures.
Topics: Aging; Animals; Antioxidants; Cardiovascular Diseases; Carnitine; Cell Line; Diabetes Mellitus, Type | 2020 |
The role of biofactors in the prevention and treatment of age-related diseases.
Topics: Aged; Cardiovascular Diseases; Dementia; Diabetes Mellitus; Dietary Fiber; Dietary Supplements; Epig | 2021 |
Mechanics Insights of Alpha-Lipoic Acid against Cardiovascular Diseases during COVID-19 Infection.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Cardiovascular Diseases; COVID-19; COVID-19 | 2021 |
Advances in the management of diabetic neuropathy.
Topics: Adjuvants, Immunologic; Amines; Anticonvulsants; Antidepressive Agents; Antioxidants; Cardiovascular | 2017 |
The protective effect of lipoic acid on selected cardiovascular diseases caused by age-related oxidative stress.
Topics: Aging; Animals; Cardiotonic Agents; Cardiovascular Diseases; Humans; Oxidative Stress; Thioctic Acid | 2015 |
[An endogenous dithiol with antioxidant properties: alpha-lipoic acid, potential uses in cardiovascular diseases].
Topics: 8,11,14-Eicosatrienoic Acid; Animal Experimentation; Animals; Antioxidants; Cardiovascular Diseases; | 2008 |
Antioxidant properties of an endogenous thiol: Alpha-lipoic acid, useful in the prevention of cardiovascular diseases.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Diabetic Neuropathies; Dietary Supplements; Endothel | 2009 |
Direct and indirect antioxidant properties of α-lipoic acid and therapeutic potential.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Chelating Agents; Diabetes Mellitus; Dietary Supplem | 2013 |
Alpha-lipoic acid and cardiovascular disease.
Topics: Antioxidants; Arteriosclerosis; Cardiovascular Diseases; Free Radical Scavengers; Humans; Lipids; Ri | 2003 |
The clinical application of metabolic therapy for cardiovascular disease.
Topics: Adaptation, Physiological; Cardiovascular Diseases; Coenzymes; Exercise; Glucose; Heart Failure; Hum | 2007 |
Use of antioxidant nutrients in the prevention and treatment of type 2 diabetes.
Topics: Antioxidants; Blood Glucose; Cardiovascular Diseases; Developed Countries; Diabetes Complications; D | 2001 |
6 trials available for thioctic acid and Cardiovascular Diseases
| Article | Year |
|---|---|
Alpha-lipoic acid improved anemia, erythropoietin resistance, maintained glycemic control, and reduced cardiovascular risk in diabetic patients on hemodialysis: a multi-center prospective randomized controlled study.
Topics: Anemia; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus; Erythropoietin; Fructosamine | 2022 |
Untargeted metabolomic on urine samples after α-lipoic acid and/or eicosapentaenoic acid supplementation in healthy overweight/obese women.
Topics: Adipose Tissue; Adult; Antioxidants; Cardiovascular Diseases; Dietary Supplements; Eicosapentaenoic | 2018 |
Effect of Alpha-Lipoic Acid Supplementation on Endothelial Function and Cardiovascular Risk Factors in Overweight/Obese Youths: A Double-Blind, Placebo-Controlled Randomized Trial.
Topics: Adolescent; Caloric Restriction; Cardiovascular Diseases; Child; Dietary Supplements; Double-Blind M | 2019 |
The effect of alpha-lipoic acid (ALA) supplementation on cardiovascular risk factors in men with chronic spinal cord injury: a clinical trial.
Topics: Adult; Anthropometry; Blood Chemical Analysis; Blood Glucose; Blood Pressure; Body Mass Index; Cardi | 2015 |
Alpha-lipoic acid improves endothelial dysfunction in patients with subclinical hypothyroidism.
Topics: Aged; Antioxidants; Asymptomatic Diseases; Brachial Artery; Cardiovascular Diseases; Endothelium, Va | 2010 |
Effect of α-lipoic acid and exercise training on cardiovascular disease risk in obesity with impaired glucose tolerance.
Topics: Antioxidants; Blood Glucose; Body Composition; Cardiovascular Diseases; Energy Intake; Exercise Ther | 2011 |
6 other studies available for thioctic acid and Cardiovascular Diseases
| Article | Year |
|---|---|
Establishment of a Drug Screening Model for Cardiac Complications of Acute Renal Failure.
Topics: Acute Kidney Injury; Animals; Animals, Genetically Modified; Cardio-Renal Syndrome; Cardiovascular D | 2021 |
[The effect of long-chain polyunsaturated higher ω-3 fatty acids, benfotiamine and α-lipoic acid on the lipid metabolism in patients with diabetes mellitus type 2 and cardiovascular autonomic neuropathy].
Topics: Aged; Aged, 80 and over; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; D | 2013 |
Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.
Topics: Animals; Anti-Obesity Agents; Antihypertensive Agents; Antioxidants; Biomarkers; Cardiotonic Agents; | 2016 |
Syntheses and characterization of lisinopril-coated gold nanoparticles as highly stable targeted CT contrast agents in cardiovascular diseases.
Topics: Animals; Cardiovascular Diseases; Contrast Media; Gold; Lisinopril; Metal Nanoparticles; Mice; Molec | 2012 |
Lipoic acid supplementation and endothelial function.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Endothelium, Vascular; Humans; Thioctic Acid | 2008 |
Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis.
Topics: Animals; Blood Circulation; Cardiovascular Diseases; Glutathione; Hemodynamics; Lipid Peroxides; Liv | 1999 |