thioctic acid has been researched along with Cardiomegaly in 5 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, its role in protecting against cardiac hypertrophy has not been elucidated." | 1.40 | Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1. ( Chai, E; Qi, Y; Zhang, L; Zhang, Y; Zou, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, C | 1 |
| Chen, X | 2 |
| Cao, Y | 1 |
| Du, Y | 1 |
| Xu, X | 1 |
| Wu, Q | 1 |
| Lin, L | 1 |
| Qin, Y | 1 |
| Meng, R | 1 |
| Gan, L | 1 |
| Zhang, J | 1 |
| Zhang, L | 1 |
| Zou, J | 2 |
| Chai, E | 1 |
| Qi, Y | 1 |
| Zhang, Y | 1 |
| Gan, X | 1 |
| Zhou, H | 1 |
| Guo, Y | 1 |
| Chen, J | 1 |
| Yang, X | 1 |
| Lei, J | 1 |
| Mervaala, E | 1 |
| Finckenberg, P | 1 |
| Lapatto, R | 1 |
| Müller, DN | 1 |
| Park, JK | 1 |
| Dechend, R | 1 |
| Ganten, D | 1 |
| Vapaatalo, H | 1 |
| Luft, FC | 1 |
| Thürich, T | 1 |
| Bereiter-Hahn, J | 1 |
| Schneider, M | 1 |
| Zimmer, G | 1 |
5 other studies available for thioctic acid and Cardiomegaly
| Article | Year |
|---|---|
Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2-associated PINK/Parkin Pathway.
Topics: Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehyd | 2023 |
Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Down-Regulation; Heart; Male; Myocytes, Card | 2014 |
Alpha-lipoic acid attenuates cardiac hypertrophy via inhibition of C/EBPβ activation.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Cardiomegaly; CCAAT-Enhancer-Binding Protein-beta; Do | 2015 |
Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Topics: Albuminuria; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; C | 2003 |
Cardioprotective effects of dihydrolipoic acid and tocopherol in right heart hypertrophy during oxidative stress.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Calcium; Cardiomegaly; Coronary Circulation; Creatine | 1998 |