Page last updated: 2024-10-19

thioctic acid and Cardiac Hypertrophy

thioctic acid has been researched along with Cardiac Hypertrophy in 5 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"However, its role in protecting against cardiac hypertrophy has not been elucidated."1.40Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1. ( Chai, E; Qi, Y; Zhang, L; Zhang, Y; Zou, J, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Shen, C1
Chen, X2
Cao, Y1
Du, Y1
Xu, X1
Wu, Q1
Lin, L1
Qin, Y1
Meng, R1
Gan, L1
Zhang, J1
Zhang, L1
Zou, J2
Chai, E1
Qi, Y1
Zhang, Y1
Gan, X1
Zhou, H1
Guo, Y1
Chen, J1
Yang, X1
Lei, J1
Mervaala, E1
Finckenberg, P1
Lapatto, R1
Müller, DN1
Park, JK1
Dechend, R1
Ganten, D1
Vapaatalo, H1
Luft, FC1
Thürich, T1
Bereiter-Hahn, J1
Schneider, M1
Zimmer, G1

Other Studies

5 other studies available for thioctic acid and Cardiac Hypertrophy

ArticleYear
Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2-associated PINK/Parkin Pathway.
    Journal of cardiovascular pharmacology, 2023, Nov-01, Volume: 82, Issue:5

    Topics: Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehyd

2023
Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1.
    European journal of pharmacology, 2014, Dec-05, Volume: 744

    Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Down-Regulation; Heart; Male; Myocytes, Card

2014
Alpha-lipoic acid attenuates cardiac hypertrophy via inhibition of C/EBPβ activation.
    Molecular and cellular endocrinology, 2015, Jan-05, Volume: 399

    Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Cardiomegaly; CCAAT-Enhancer-Binding Protein-beta; Do

2015
Lipoic acid supplementation prevents angiotensin II-induced renal injury.
    Kidney international, 2003, Volume: 64, Issue:2

    Topics: Albuminuria; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; C

2003
Cardioprotective effects of dihydrolipoic acid and tocopherol in right heart hypertrophy during oxidative stress.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Calcium; Cardiomegaly; Coronary Circulation; Creatine

1998