thioctic acid has been researched along with Cardiac Hypertrophy in 5 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, its role in protecting against cardiac hypertrophy has not been elucidated." | 1.40 | Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1. ( Chai, E; Qi, Y; Zhang, L; Zhang, Y; Zou, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, C | 1 |
| Chen, X | 2 |
| Cao, Y | 1 |
| Du, Y | 1 |
| Xu, X | 1 |
| Wu, Q | 1 |
| Lin, L | 1 |
| Qin, Y | 1 |
| Meng, R | 1 |
| Gan, L | 1 |
| Zhang, J | 1 |
| Zhang, L | 1 |
| Zou, J | 2 |
| Chai, E | 1 |
| Qi, Y | 1 |
| Zhang, Y | 1 |
| Gan, X | 1 |
| Zhou, H | 1 |
| Guo, Y | 1 |
| Chen, J | 1 |
| Yang, X | 1 |
| Lei, J | 1 |
| Mervaala, E | 1 |
| Finckenberg, P | 1 |
| Lapatto, R | 1 |
| Müller, DN | 1 |
| Park, JK | 1 |
| Dechend, R | 1 |
| Ganten, D | 1 |
| Vapaatalo, H | 1 |
| Luft, FC | 1 |
| Thürich, T | 1 |
| Bereiter-Hahn, J | 1 |
| Schneider, M | 1 |
| Zimmer, G | 1 |
5 other studies available for thioctic acid and Cardiac Hypertrophy
| Article | Year |
|---|---|
Alpha-lipoic Acid Protects Against Chronic Alcohol Consumption-induced Cardiac Damage by the Aldehyde Dehydrogenase 2-associated PINK/Parkin Pathway.
Topics: Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Aldehyd | 2023 |
Alpha-lipoic acid attenuates cardiac hypertrophy via downregulation of PARP-2 and subsequent activation of SIRT-1.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Down-Regulation; Heart; Male; Myocytes, Card | 2014 |
Alpha-lipoic acid attenuates cardiac hypertrophy via inhibition of C/EBPβ activation.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Cardiomegaly; CCAAT-Enhancer-Binding Protein-beta; Do | 2015 |
Lipoic acid supplementation prevents angiotensin II-induced renal injury.
Topics: Albuminuria; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; C | 2003 |
Cardioprotective effects of dihydrolipoic acid and tocopherol in right heart hypertrophy during oxidative stress.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Calcium; Cardiomegaly; Coronary Circulation; Creatine | 1998 |