thioctic acid has been researched along with Brain Injuries in 11 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VPA) is an effective drug, which is preferred for the treatments of epilepsy and various kinds of seizures." | 1.56 | Alpha-lipoic acid prevents brain injury in rats administered with valproic acid. ( Bilgin Sokmen, B; Turkyilmaz, IB; Yanardag, R, 2020) |
| "A total of 1." | 1.42 | Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury. ( Bailes, JE; Huber, JD; Lee, JM; Logsdon, AF; Lucke-Wold, BP; Naser, ZJ; Robson, MJ; Rosen, CL; Smith, KE; Turner, RC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Turkyilmaz, IB | 1 |
| Bilgin Sokmen, B | 1 |
| Yanardag, R | 1 |
| Rocamonde, B | 3 |
| Paradells, S | 4 |
| Barcia, C | 2 |
| Garcia Esparza, A | 1 |
| Soria, JM | 4 |
| Zipancic, I | 1 |
| Martínez-Losa, MM | 1 |
| García Esparza, MÁ | 2 |
| Bosch-Morell, F | 1 |
| Alvarez-Dolado, M | 1 |
| Ozbal, S | 1 |
| Cankurt, U | 1 |
| Tugyan, K | 1 |
| Pekcetin, C | 1 |
| Sisman, AR | 1 |
| Gunduz, K | 1 |
| Micili, SC | 1 |
| Wei, W | 1 |
| Wang, H | 1 |
| Wu, Y | 1 |
| Ding, K | 1 |
| Li, T | 1 |
| Cong, Z | 1 |
| Xu, J | 1 |
| Zhou, M | 1 |
| Huang, L | 1 |
| Ding, H | 1 |
| Wu, H | 1 |
| Lucke-Wold, BP | 1 |
| Naser, ZJ | 1 |
| Logsdon, AF | 1 |
| Turner, RC | 1 |
| Smith, KE | 1 |
| Robson, MJ | 1 |
| Bailes, JE | 1 |
| Lee, JM | 1 |
| Rosen, CL | 1 |
| Huber, JD | 1 |
| Vives, MS | 1 |
| Sauro, S | 1 |
| Ramos, CM | 1 |
| Pradas, MM | 1 |
| Toklu, HZ | 1 |
| Hakan, T | 1 |
| Biber, N | 1 |
| Solakoğlu, S | 1 |
| Oğünç, AV | 1 |
| Sener, G | 1 |
| Barcia, JM | 1 |
| García Verdugo, JM | 1 |
| Miranda, M | 1 |
| Romero Gómez, FJ | 1 |
| Flanary, BE | 1 |
| Streit, WJ | 1 |
| Shohami, E | 1 |
| Gati, I | 1 |
| Beit-Yannai, E | 1 |
| Trembovler, V | 1 |
| Kohen, R | 1 |
11 other studies available for thioctic acid and Brain Injuries
| Article | Year |
|---|---|
Alpha-lipoic acid prevents brain injury in rats administered with valproic acid.
Topics: Animals; Antioxidants; Brain Injuries; Dose-Response Relationship, Drug; Female; Glutathione; Lipid | 2020 |
Lipoic acid treatment after brain injury: study of the glial reaction.
Topics: Animals; Antioxidants; Astrocytes; Blood-Brain Barrier; Brain; Brain Injuries; Disease Models, Anima | 2013 |
Lipoic acid and bone marrow derived cells therapy induce angiogenesis and cell proliferation after focal brain injury.
Topics: Angiogenesis Inducing Agents; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Brain Injurie | 2015 |
The effects of α-lipoic acid on immature rats with traumatic brain injury.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Chemistry; Brain Injuries; In Situ Nick-End Labeling; | 2015 |
Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injury.
Topics: Animals; Apoptosis; Brain Edema; Brain Injuries; Male; Mitochondria; Neurons; Oxidative Stress; Rats | 2015 |
Amelioration of nicotinamide adenine dinucleotide phosphate-oxidase mediated stress reduces cell death after blast-induced traumatic brain injury.
Topics: Animals; Apoptosis; Blast Injuries; Brain Injuries; Male; NADPH Oxidases; Oxidative Stress; Rats; Ra | 2015 |
Combined application of polyacrylate scaffold and lipoic acid treatment promotes neural tissue reparation after brain injury.
Topics: Acrylates; Amylopectin; Animals; Brain; Brain Injuries; Brain Injuries, Traumatic; Male; Plastics; R | 2016 |
The protective effect of alpha lipoic acid against traumatic brain injury in rats.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Injuries; Glutathione; Interleukin-1b | 2009 |
Neuroprotection of lipoic acid treatment promotes angiogenesis and reduces the glial scar formation after brain injury.
Topics: Animals; Antioxidants; Blotting, Western; Brain Injuries; Chromatography, High Pressure Liquid; Cica | 2012 |
Alpha-tocopherol (vitamin E) induces rapid, nonsustained proliferation in cultured rat microglia.
Topics: alpha-Tocopherol; Animals; Animals, Newborn; Antioxidants; Brain; Brain Injuries; Cell Division; Cel | 2006 |
Closed head injury in the rat induces whole body oxidative stress: overall reducing antioxidant profile.
Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Brain Injuries; Carnosine; Carotenoids; Free Radical Sc | 1999 |